3,4-Difluoroanisole
- CAS No.
- 115144-40-6
- Chemical Name:
- 3,4-Difluoroanisole
- Synonyms
- 3,4-DIFLUORO-1-METHOXYBENZENE;3,4-DIFLUOROANISOLE;3,4-Difluoroanisole>3,4-Difluoroanisole98%;3,4,5-TRIFLUORO ANISOLE;3,4-Difluoroanisole 98%;3,4-Difluoroanisole, 97%;"3,4-Difluoroanisole, 99%";1,2-DIFLUORO-4-METHOXY-BENZENE;Benzene, 1,2-difluoro-4-methoxy-
- CBNumber:
- CB9155486
- Molecular Formula:
- C7H6F2O
- Molecular Weight:
- 144.12
- MDL Number:
- MFCD00010730
- MOL File:
- 115144-40-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 101.45°C (rough estimate) |
|---|---|
| Density | 1.216 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | 131 °F |
| storage temp. | Sealed in dry,Room Temperature |
| form | Liquid |
| color | Clear colorless |
| Specific Gravity | 1.216 |
| BRN | 6717610 |
| InChI | InChI=1S/C7H6F2O/c1-10-5-2-3-6(8)7(9)4-5/h2-4H,1H3 |
| InChIKey | DSEVNUCNUTYYHW-UHFFFAOYSA-N |
| SMILES | C1(F)=CC=C(OC)C=C1F |
| CAS DataBase Reference | 115144-40-6(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H226-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P303+P361+P353-P305+P351+P338-P405-P501a-P210-P233-P240-P241+P242+P243-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P403+P235-P501 | |||||||||
| Hazard Codes | Xi,F,Xn | |||||||||
| Risk Statements | 10-36/37/38 | |||||||||
| Safety Statements | 16-26-36-7/9 | |||||||||
| RIDADR | UN 1993 3/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Flammable | |||||||||
| HazardClass | 3 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29093090 | |||||||||
| Limited Quantities | 5.0 L (1.3 gallons) (liquid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) | |||||||||
| NFPA 704 |
|
3,4-Difluoroanisole price More Price(59)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | D2856 | 3,4-Difluoroanisole >97.0%(GC) | 115144-40-6 | 5g | $51 | 2026-04-30 | Buy |
| TCI Chemical | D2856 | 3,4-Difluoroanisole >97.0%(GC) | 115144-40-6 | 25g | $153 | 2026-04-30 | Buy |
| Usbiological | 273314 | 3,4-Difluoroanisole Asreported | 115144-40-6 | 25g | $433 | 2026-06-03 | Buy |
| Usbiological | 273314 | 3,4-Difluoroanisole Asreported | 115144-40-6 | 50g | $616 | 2026-06-03 | Buy |
| Usbiological | 273314 | 3,4-Difluoroanisole Asreported | 115144-40-6 | 100g | $835 | 2026-06-03 | Buy |
3,4-Difluoroanisole Chemical Properties, Uses, Production
Uses
3,4-Difluoroanisole is an organic intermediate that can be prepared by etherifying 3,4-difluorophenol with iodomethane.
Chemical Properties
CLEAR COLOURLESS LIQUID
Synthesis Reference(s)
[1] Method for preparing 3,4-difluoroanisole. CN105523904A
Synthesis
The method for preparing 3,4-difluoroanisole includes the steps that compound 3,4-difluorophenol is dissolved in acetonitrile, potassium carbonate is weighed, methyl iodide is dripped, and the mixture is reacted overnight at an indoor temperature; thin-1ayer chromatography is carried out on the next day, and it is discovered that the raw materials are completely reacted; reaction liquid is poured into water to be fully stirred, the lower layer organic phase is separated, then dichloromethane and water are added, and full washing and separation are carried out; afterwards, washing with water is conducted twice, and the organic phase is separated, dried and subjected to atmospheric distillation; the product, dichloromethane and residual acetonitrile are azeotropic, a vacuum pump is used for conducting reduced pressure distillation from the temperature of 60°C, colorless clear liquid is steamed out when the temperature is raised to 120°C, and accordingly the compound 3,4-difluoroanisole is obtained.
3,4-Difluoroanisole Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Ark Pharm, Inc. | 847-367-3680 | sales@arkpharminc.com | United States | 1669 | 56 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Shanghai Sinch Parmaceuticals Tech. Co. Ltd. | +86-21-54098501 | sales@sinch.com.cn | China | 11592 | 64 |
View Latest Price from 3,4-Difluoroanisole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-25 | 3,4-Difluoroanisole
115144-40-6
|
$2.00-5.00 | 1kg | 99% | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
 |
2026-05-28 | 3,4-Difluoroanisole
115144-40-6
|
$2.00-5.00 | 1KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD | |
 |
2019-09-11 | 3,4-Difluoroanisole
115144-40-6
|
$1.00 | 1KG | 98 | 200kg | Career Henan Chemical Co |
-
- 3,4-Difluoroanisole
115144-40-6
- $2.00-5.00
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- 3,4-Difluoroanisole
115144-40-6
- $2.00-5.00
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
-
- 3,4-Difluoroanisole
115144-40-6
- $1.00
- 98
- Career Henan Chemical Co
