5-Hydroxyisoquinoline
- CAS No.
- 2439-04-5
- Chemical Name:
- 5-Hydroxyisoquinoline
- Synonyms
- NSC 51787;5-ISOQUINOLINOL;ISOQUINOLIN-5-OL;Isoquinoline-5-ol;5-Hydroxyisoquinolne;5-Hydroxyisoquin din;5-HYDROXYISOQUINOLINE;5-Hydroxyisoquin dine;5-Hydroxyisoquinoline90%;5-Hydroxyisoquinoline>
- CBNumber:
- CB9174379
- Molecular Formula:
- C9H7NO
- Molecular Weight:
- 145.16
- MDL Number:
- MFCD00006906
- MOL File:
- 2439-04-5.mol
- MSDS File:
- SDS
| Melting point | 213-215 |
|---|---|
| Boiling point | 264.27°C (rough estimate) |
| Density | 1.1555 (rough estimate) |
| refractive index | 1.4500 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| pka | 8.53±0.40(Predicted) |
| form | Granular Powder |
| color | Beige |
| InChI | InChI=1S/C9H7NO/c11-9-3-1-2-7-6-10-5-4-8(7)9/h1-6,11H |
| InChIKey | CSNXUYRHPXGSJD-UHFFFAOYSA-N |
| SMILES | C1C2=C(C(O)=CC=C2)C=CN=1 |
| CAS DataBase Reference | 2439-04-5(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-21/22 | |||||||||
| Safety Statements | 26-37/39-36/37/39-36 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 29334900 | |||||||||
| NFPA 704 |
|
5-Hydroxyisoquinoline price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | H33207 | 5-Hydroxyisoquinoline technical grade, 90% | 2439-04-5 | 5g | $85 | 2025-07-31 | Buy |
| Sigma-Aldrich | H33207 | 5-Hydroxyisoquinoline technical grade, 90% | 2439-04-5 | 25g | $436 | 2023-06-20 | Buy |
| TCI Chemical | H1259 | 5-Hydroxyisoquinoline >96.0%(GC)(T) | 2439-04-5 | 5g | $198 | 2025-07-31 | Buy |
| TCI Chemical | H1259 | 5-Hydroxyisoquinoline >96.0%(GC)(T) | 2439-04-5 | 25g | $698 | 2025-07-31 | Buy |
| TRC | H953260 | 5-Hydroxyisoquinoline | 2439-04-5 | 100mg | $50 | 2021-12-16 | Buy |
5-Hydroxyisoquinoline Chemical Properties,Uses,Production
Chemical Properties
beige granular powder
Uses
5-Hydroxyisoquinoline is a reagent used in the preparation of PARP inhibitor.
Synthesis
27655-40-9
2439-04-5
The general procedure for the synthesis of 5-hydroxyisoquinoline from 5-isoquinolinesulfonic acid is as follows: 23 g of 5-isoquinolinesulfonic acid is added to 400 ml of water, followed by 60 g of sodium hydroxide. The reaction mixture was heated to reflux and stirred continuously under this condition for 24 hours. Upon completion of the reaction, the mixture was cooled to room temperature and the pH was adjusted with dilute hydrochloric acid to 5. Then, ethyl acetate was added for extraction and the organic phase was separated and collected. The organic phase was concentrated and the resulting residue was purified by silica gel column chromatography to yield 16 g of 5-hydroxyisoquinoline.
References
[1] Acta Poloniae Pharmaceutica, 1994, vol. 51, # 6, p. 479 - 482
[2] Patent: CN107778231, 2018, A. Location in patent: Paragraph 0023; 0024
5-Hydroxyisoquinoline Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29733 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29855 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49730 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 | 1022@dideu.com | China | 3889 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
View Lastest Price from 5-Hydroxyisoquinoline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-08-15 | 5-Hydroxyisoquinoline
2439-04-5
|
US $0.00 / KG | 1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2022-03-07 | 5-Hydroxyisoquinoline
2439-04-5
|
US $1.10 / g | 1g | 99.00% | 100 Tons | Dideu Industries Group Limited | |
 |
2022-02-19 | 5-Hydroxyisoquinoline | US $0.00 / KG | 1KG | 97.7% | 100 tons | Honest Joy Holdings Limited |
-
- 5-Hydroxyisoquinoline
2439-04-5
- US $0.00 / KG
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- 5-Hydroxyisoquinoline
2439-04-5
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
-
- 5-Hydroxyisoquinoline
- US $0.00 / KG
- 97.7%
- Honest Joy Holdings Limited
2439-04-5(5-Hydroxyisoquinoline)Related Search:
1of4
