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4-Amino-6-chlorobenzene-1,3-disulfonamide

4-Amino-6-chlorobenzene-1,3-disulfonamide structure

CAS No.: 121-30-2

Chemical Name:: 4-Amino-6-chlorobenzene-1,3-disulfonamide

Synonyms: Salmid;Idorese;NSC 93772;3-disulfonamide;Fine sulfonamides;Sperm sulfonamide;4-AMino-6-chloro-1;CHLORAMINOPHENAMIDE;Chloruminophenamide;Chloroaminophenamide

CBNumber:: CB9181795

Molecular Formula:: C6H8ClN3O4S2

Molecular Weight:: 285.73

MDL Number:: MFCD00007933

MOL File:: 121-30-2.mol

MSDS File:: SDS

Last updated:2025-07-04 14:24:19

Product description	Number	Pack Size	Price
4-Amino-6-chloro-1,3-benzenedisulfonamide 98%	308560	5g	$29
4-Amino-6-chlorobenzene-1-3-disulfonamide British Pharmacopoeia (BP) Reference Standard	BP010	50mg	$234
Benzothiadiazine Related Compound A United States Pharmacopeia (USP) Reference Standard	1057507	100mg	$1360
4-Amino-6-chloro-1,3-benzenedisulfonamide >98.0%(N)	A1362	25g	$34
4-Amino-6-chloro-1,3-benzenedisulfonamide ≥98%	21309	1g	$20
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4-Amino-6-chlorobenzene-1,3-disulfonamide Properties

Melting point	257-261 °C(lit.)
Boiling point	614.4±65.0 °C(Predicted)
Density	1.584 (estimate)
refractive index	1.6100 (estimate)
storage temp.	2-8°C
solubility	DMSO (Slightly), Methanol (Slightly)
pka	9.24±0.60(Predicted)
form	Powder
color	White to off-white
Merck	14,2076
BRN	1083877
InChI	InChI=1S/C6H8ClN3O4S2/c7-3-1-4(8)6(16(10,13)14)2-5(3)15(9,11)12/h1-2H,8H2,(H2,9,11,12)(H2,10,13,14)
InChIKey	IHJCXVZDYSXXFT-UHFFFAOYSA-N
SMILES	C1(S(N)(=O)=O)=C(Cl)C=C(N)C(S(N)(=O)=O)=C1
CAS DataBase Reference	121-30-2(CAS DataBase Reference)
FDA UNII	3A52O8YREJ
EPA Substance Registry System	1,3-Benzenedisulfonamide, 4-amino-6-chloro- (121-30-2)
UNSPSC Code	41116107
NACRES	NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319
Precautionary statements	P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
Hazard Codes	T
Risk Statements	23/24-33-20/21
Safety Statements	28-36/37-36/37/39-26-22
WGK Germany	3
HazardClass	IRRITANT
HS Code	29350090

4-Amino-6-chlorobenzene-1,3-disulfonamide price More Price(33)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	308560	4-Amino-6-chloro-1,3-benzenedisulfonamide 98%	121-30-2	5g	$29	2025-07-31	Buy
Sigma-Aldrich	BP010	4-Amino-6-chlorobenzene-1-3-disulfonamide British Pharmacopoeia (BP) Reference Standard	121-30-2	50mg	$234	2025-07-31	Buy
Sigma-Aldrich	1057507	Benzothiadiazine Related Compound A United States Pharmacopeia (USP) Reference Standard	121-30-2	100mg	$1360	2025-07-31	Buy
TCI Chemical	A1362	4-Amino-6-chloro-1,3-benzenedisulfonamide >98.0%(N)	121-30-2	25g	$34	2025-07-31	Buy
Cayman Chemical	21309	4-Amino-6-chloro-1,3-benzenedisulfonamide ≥98%	121-30-2	1g	$20	2024-03-01	Buy

Product number	Packaging	Price	Buy
308560	5g	$29	Buy
BP010	50mg	$234	Buy
1057507	100mg	$1360	Buy
A1362	25g	$34	Buy
21309	1g	$20	Buy

4-Amino-6-chlorobenzene-1,3-disulfonamide Chemical Properties,Uses,Production

Description

4-Amino-6-chlorobenzene-1,3-disulfonamide is obtained by treating the chloride with ammonia in tert-butanol and concentrating the solution by evaporation; the yield is 80 %. Condensation with formic acid gives 6-chloro-7-sulfamoyl-1,2,4-benzothiadiazine 1,1-dioxide, an important diuretic.

Chemical Properties

Light Brown Solid

Uses

Diuretic.

Uses

4-Amino-6-chloro-1,3-benzenedisulfonamide was used in the synthesis of deuterated thiazides by undergoing condensation with appropriately labeled aldehydes.

Definition

ChEBI: Chloraminophenamide is a sulfonamide.

General Description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

4-Amino-6-chlorobenzene-1,3-disulfonamide synthesis

Synthesis of 4-Amino-6-chlorobenzene-1,3-disulfonamide from 3-Chloroaniline

4-Amino-6-chlorobenzene-1,3-disulfonamide Preparation Products And Raw materials

Raw materials

Chloramine-T 3-Chloroaniline 4-AMINO-6-CHLORO-BENZENE-1,3-DISULFONYL DICHLORIDE Hydrochlorothiazide Hydrochlorothiazide Impurity 28

Hydrochlorothiazide Impurity 4 Trichlormethiazide

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Preparation Products

ethiazide Chlorothiazide 4-AMINO-5,6-DICHLOROBENZENE-1,3-DISULFONAMIDE 3-Des(allylthio)Methyl-3-chloroMethyl Althiazide EX5004

4-Amino-6-chlorobenzene-1,3-disulfonamide Suppliers

Global( 421)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Changzhou Guiding Bio-Tech. Co.,Ltd.	+86-519-519-86686860 +8618795626222	ning@guiding-bio.com	China	299	58
Moxin Chemicals	+86-17320513646 +8617320513646	anna@molcoo.com	China	10000	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21620	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29852	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58
Shandong chuangyingchemical Co., Ltd.	18853181302	sale@chuangyingchem.com	CHINA	5906	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14332	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49975	58
Antai Fine Chemical Technology Co.,Limited	18503026267	info@antaichem.com	CHINA	9636	58

Supplier	Advantage
Changzhou Guiding Bio-Tech. Co.,Ltd.	58
Moxin Chemicals	58
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
Hubei Jusheng Technology Co.,Ltd.	58
Hubei xin bonus chemical co. LTD	58
Shandong chuangyingchemical Co., Ltd.	58
Standardpharm Co. Ltd.	58
CONIER CHEM AND PHARMA LIMITED	58
Antai Fine Chemical Technology Co.,Limited	58

View Lastest Price from 4-Amino-6-chlorobenzene-1,3-disulfonamide manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-10-14	4-Amino-6-chlorobenzene-1,3-disulfonamide 121-30-2	US $0.00-0.00 / Kg/Drum	1KG	98%min	500kg	WUHAN FORTUNA CHEMICAL CO., LTD
2025-07-31	Hydrochlorothiazide EP Impurity B 121-30-2	US $0.00-0.00 / mg	10mg	98	100000	Moxin Chemicals
2022-08-26	4-Amino-6-chlorobenzene-1,3-disulfonamide 121-30-2	US $1.10 / g	1g	99.00%	100 Tons Min	Dideu Industries Group Limited

4-Amino-6-chlorobenzene-1,3-disulfonamide
121-30-2
US $0.00-0.00 / Kg/Drum
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

Hydrochlorothiazide EP Impurity B
121-30-2
US $0.00-0.00 / mg
98
Moxin Chemicals

4-Amino-6-chlorobenzene-1,3-disulfonamide
121-30-2
US $1.10 / g
99.00%
Dideu Industries Group Limited

4-Amino-6-chlorobenzene-1,3-disulfonamide Spectrum

4-Amino-6-chlorobenzene-1,3-disulfonamide(121-30-2)MS 4-Amino-6-chlorobenzene-1,3-disulfonamide(121-30-2)¹HNMR 4-Amino-6-chlorobenzene-1,3-disulfonamide(121-30-2)¹³CNMR 4-Amino-6-chlorobenzene-1,3-disulfonamide(121-30-2)IR1 4-Amino-6-chlorobenzene-1,3-disulfonamide(121-30-2)IR2 4-Amino-6-chlorobenzene-1,3-disulfonamide(121-30-2)Raman

121-30-2(4-Amino-6-chlorobenzene-1,3-disulfonamide )Related Search:

Chlorothiazide 4-Chloroaniline Glycine 6-Aminocaproic acid 2,6-Dichloroaniline

Chlorobenzene 3-Chloroaniline ALTRENOGEST 2-Chloroaniline Hydrochlorothiazide

DL-Phenylalanine N-[[7-(Aminosulfonyl)-6-chloro-2,3-dihydro-1,1-dioxo-4H-1,2,4-benzothiadiazin-4-yl]methyl]-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-Dioxode Tris(hydroxymethyl)aminomethane 3-Methyl-4H-1,2,4-benzothiadiazine 1,1-dioxide 6,7-Dichloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide

4-AMINO-6-CHLORO-BENZENE-1,3-DISULFONYL DICHLORIDE HYDROCHLOROTHIAZIDE-3,3-D2 Hydrochlorothiazide-13C,d2

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4-amino-6-chloro-3-benzenedisulfonamide 5-Chloro-2,4-bis(sulfonamido)aniline 4-AMino-6-chloro-1,3-benzenedisulfonaMide 98% Benzothiadiazine realted compound A 4-amino-6-chloro-1,3-benzenedisulphonamide Hydrochlorothiazide EP Impurity B LABOTEST-BB LT00261357 CHLORAMINOPHENAMIDE 5-Chloro-2,4-disulfamoylaniline 5-CHLORO-2,4-BIS(SULFONAMIDE)ANILINE Chloraminophenamide 5(3)-Chloroaniline-2,4(4,6)-disulfonamide 5-Chloro-2,4-bis(sulfonamide)aniline Hydrochlorothiazide IMpurity-B(EP) Hydrochlorothiazide IMpurity B (4-AMino-6-chlorobenzene-1,3-disulphonaMide, SalaMide) 1,3-Disulfonamide, 4-amino-6-chlorobenzene- m-Benzenedisulfonamide, 4-am m-Benzenedisulfonamide, 4-amino-6-chloro- (8CI) Salmid Fine sulfonamides 4-Amino-6-chlorobenzene-1,3-disulfonamide≥?99.0% Essence of sulfanilamide 3-disulfonamide 4-Amino-6-chlorobenzene-1 Benzothiadiazine USP RC A Compound Amiloride Hydrochloride Tablets Impurity Ⅰ:4-Amino-6-chlorobenzene-1,3-disulfonamide 3-Chloro-4,6-disulfamoylaniline 4-AMINO-6-CHLOROBENZENE-1,3-DISULFONAMIDE 4-AMINO-6-CHLORO-BENZENE-1,3-DISULFONIC ACID DIAMIDE 4-AMINO-6-CHLORO-1,3-BENZENEDISULFONAMIDE 5(3)-CHLOROANILINE-2,4(4,6)-DISULFONAMIDE 4-Amino-6-Chloro-1,3-Benzendisulfonamide 4-Amino-6-Chloro-1,3-Benzenedisufonamide 1-AMINO-3-CHLORO-4,6-BENZENE- DISULFONAMIDE Chloroaminophenamide Idorese 3-Chloro-4,6-disulfamylaniline 4-Amino-6-chlorobenzene-1,3-bissulfonamide 4-Chloro-6-aminobenzene-1,3-disulfonamide 4-azanyl-6-chloro-benzene-1,3-disulfonamide 4-Amino-6-chloro-1,3-benzenedisulfonamide,3-Chloroaniline-4,6-disulfonamide, 4-Amino-6-chlorobenzene-1,3-disulfonamide Benzothiadiazine Related CoMpound A Chloruminophenamide 1,3-Benzenedisulfonamide, 4-amino-6-chloro- 3-chloroaniline-4,6-disulfonamide 5-CHLORO-2,4-DISULFAMYLANILINE 4-AMINO-6-CHLORO-1,3-BENZENEDISULFONAMIDE 99+% 3-benzenedisulfonaMide 4-AMino-6-chloro-1 4-AMino-6-chloro-M-benzenedisulfonaMide NSC 93772 4-AMINO-6-CHLORO-1,3-BENZENDISULFAMIDEHYDROCHLOROTHIAZIDE Benzothiadiazine Related Compound A (100 mg) (4-Amino-6-chloro-1,3-benzenedisulfonamide) 4-aMino-6-chlorobenzen-1,3-disulphonaMide(salaMide) 4-Amino-6-Chloro-1,2-Benzenedisulfonamide Benzothiadiazine impurity A 5-Chloroaniline 2, 4-disulfonamide 4-Amino-6-chlorobenzene-1,3-disulph Amino benzenedisulfonamide 4-Amino-6-chlorobenzene-1,3-disulfonamide ISO 9001：2015 REACH