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4-Amino-6-chlorobenzene-1,3-disulfonamide

4-Amino-6-chlorobenzene-1,3-disulfonamide Structure
4-Amino-6-chlorobenzene-1,3-disulfonamide structure
CAS No.
121-30-2
Chemical Name:
4-Amino-6-chlorobenzene-1,3-disulfonamide
Synonyms
CHLORAMINOPHENAMIDE;4-AMINO-6-CHLORO-1,3-BENZENEDISULFONAMIDE;Benzothiadiazine Related CoMpound A;Hydrochlorothiazide EP Impurity B;4-amino-6-chloro-1,3-benzenedisulphonamide;Salmid;Idorese;NSC 93772;3-disulfonamide;Fine sulfonamides
CBNumber:
CB9181795
Molecular Formula:
C6H8ClN3O4S2
Molecular Weight:
285.73
MDL Number:
MFCD00007933
MOL File:
121-30-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 05:18:18
Request For Quotation

4-Amino-6-chlorobenzene-1,3-disulfonamide Properties

Melting point 257-261 °C(lit.)
Boiling point 614.4±65.0 °C(Predicted)
Density 1.584 (estimate)
refractive index 1.6100 (estimate)
storage temp. 2-8°C
solubility DMSO (Slightly), Methanol (Slightly)
pka 9.24±0.60(Predicted)
form Powder
color White to off-white
Merck 14,2076
BRN 1083877
InChI InChI=1S/C6H8ClN3O4S2/c7-3-1-4(8)6(16(10,13)14)2-5(3)15(9,11)12/h1-2H,8H2,(H2,9,11,12)(H2,10,13,14)
InChIKey IHJCXVZDYSXXFT-UHFFFAOYSA-N
SMILES C1(S(N)(=O)=O)=C(Cl)C=C(N)C(S(N)(=O)=O)=C1
CAS DataBase Reference 121-30-2(CAS DataBase Reference)
FDA UNII 3A52O8YREJ
EPA Substance Registry System 1,3-Benzenedisulfonamide, 4-amino-6-chloro- (121-30-2)
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
PPE Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Hazard Codes  T
Risk Statements  23/24-33-20/21
Safety Statements  28-36/37-36/37/39-26-22
WGK Germany  3
TSCA  TSCA listed
HazardClass  IRRITANT
HS Code  29350090
Storage Class 11 - Combustible Solids
REACH Registrations Active

4-Amino-6-chlorobenzene-1,3-disulfonamide price More Price(77)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 308560 4-Amino-6-chloro-1,3-benzenedisulfonamide 98% 121-30-2 5g $30.9 2026-04-30 Buy
Sigma-Aldrich BP010 4-Amino-6-chlorobenzene-1-3-disulfonamide British Pharmacopoeia (BP) Reference Standard 121-30-2 50mg $251 2026-04-30 Buy
Sigma-Aldrich 1057507 Benzothiadiazine Related Compound A United States Pharmacopeia (USP) Reference Standard 121-30-2 100mg $1460 2026-04-30 Buy
TCI Chemical A1362 4-Amino-6-chloro-1,3-benzenedisulfonamide >98.0%(N) 121-30-2 25g $25 2026-04-30 Buy
Cayman Chemical 21309 4-Amino-6-chloro-1,3-benzenedisulfonamide ≥98% 121-30-2 1g $22 2026-04-30 Buy
Product number Packaging Price Buy
308560 5g $30.9 Buy
BP010 50mg $251 Buy
1057507 100mg $1460 Buy
A1362 25g $25 Buy
21309 1g $22 Buy

4-Amino-6-chlorobenzene-1,3-disulfonamide Chemical Properties,Uses,Production

Description

4-Amino-6-chlorobenzene-1,3-disulfonamide is obtained by treating the chloride with ammonia in tert-butanol and concentrating the solution by evaporation; the yield is 80 %. Condensation with formic acid gives 6-chloro-7-sulfamoyl-1,2,4-benzothiadiazine 1,1-dioxide, an important diuretic.

Chemical Properties

Light Brown Solid

Uses

Diuretic.

Uses

4-Amino-6-chloro-1,3-benzenedisulfonamide was used in the synthesis of deuterated thiazides by undergoing condensation with appropriately labeled aldehydes.

Definition

ChEBI: Chloraminophenamide is a sulfonamide.

General Description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

4-Amino-6-chlorobenzene-1,3-disulfonamide synthesis

108-42-9
121-30-2
Synthesis of 4-Amino-6-chlorobenzene-1,3-disulfonamide from 3-Chloroaniline

4-Amino-6-chlorobenzene-1,3-disulfonamide Preparation Products And Raw materials

Raw materials

Chloramine-T 3-Chloroaniline 4-Amino-6-chloro-benzene-1,3-disulfonyl dichloride Hydrochlorothiazide Hydrochlorothiazide Impurity 28
Hydrochlorothiazide Impurity 4 Trichlormethiazide

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Preparation Products

ethiazide Chlorothiazide 4-Amino-5,6-dichlorobenzene-1,3-disulfonamide 3-Des(allylthio)Methyl-3-chloroMethyl Althiazide EX5004

4-Amino-6-chlorobenzene-1,3-disulfonamide Suppliers

Global( 428)Suppliers
Supplier Tel Email Country ProdList Advantage
SUZHOU AUSUN CHEMICAL CO., LTD. 0512-68244182 15850237342 ausunjoy@163.com China 29 58
Wuhan woxuan Technology Co., Ltd 13322067656 3199863540@qq.com China 3905 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
INTATRADE GmbH +49 3493/605464 sales@intatrade.de Germany 3563 66
TAIYUAN RHF CO.,LTD. +86 351 7031519 sales@RHFChem.com China 2334 56
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Supplier Advantage
SUZHOU AUSUN CHEMICAL CO., LTD. 58
Wuhan woxuan Technology Co., Ltd 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
INTATRADE GmbH 66
TAIYUAN RHF CO.,LTD. 56
TCI (Shanghai) Development Co., Ltd. 81
Energy Chemical 61
Beijing Ouhe Technology Co., Ltd 60
Pure Chemistry Scientific Inc. 62

Related articles

View Lastest Price from 4-Amino-6-chlorobenzene-1,3-disulfonamide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Amino-6-chlorobenzene-1,3-disulfonamide pictures 2026-09-11 4-Amino-6-chlorobenzene-1,3-disulfonamide
121-30-2
 1KG 98%min 500kg WUHAN FORTUNA CHEMICAL CO., LTD
4-Amino-6-chlorobenzene-1,3-disulfonamide pictures 2026-08-20 4-Amino-6-chlorobenzene-1,3-disulfonamide
121-30-2
 $1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited
Hydrochlorothiazide EP Impurity B pictures 2025-12-16 Hydrochlorothiazide EP Impurity B
121-30-2
 10mg 98 100000 Moxin Chemicals

4-Amino-6-chlorobenzene-1,3-disulfonamide Spectrum

4-Amino-6-chlorobenzene-1,3-disulfonamide(121-30-2)MS4-Amino-6-chlorobenzene-1,3-disulfonamide(121-30-2)1HNMR4-Amino-6-chlorobenzene-1,3-disulfonamide(121-30-2)13CNMR4-Amino-6-chlorobenzene-1,3-disulfonamide(121-30-2)IR14-Amino-6-chlorobenzene-1,3-disulfonamide(121-30-2)IR24-Amino-6-chlorobenzene-1,3-disulfonamide(121-30-2)Raman

121-30-2(4-Amino-6-chlorobenzene-1,3-disulfonamide )Related Search:

Hydrochlorothiazide 4-Chloroaniline 6-Aminocaproic acid 2,6-Dichloroaniline Chlorobenzene
3-Chloroaniline 2-Chloroaniline Chlorothiazide DL-Phenylalanine N-[[7-(Aminosulfonyl)-6-chloro-2,3-dihydro-1,1-dioxo-4H-1,2,4-benzothiadiazin-4-yl]methyl]-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-Dioxode
Tris(hydroxymethyl)aminomethane Glycine Aminoethoxyvinyl glycine hydrochloride 3-Methyl-4H-1,2,4-benzothiadiazine 1,1-dioxide 6,7-Dichloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
4-Amino-6-chloro-benzene-1,3-disulfonyl dichloride Hydrochlorothiazide-3,3-d2 Hydrochlorothiazide-13C,d2

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4-amino-6-chloro-3-benzenedisulfonamide 5-Chloro-2,4-bis(sulfonamido)aniline 4-AMino-6-chloro-1,3-benzenedisulfonaMide 98% Benzothiadiazine realted compound A LABOTEST-BB LT00261357 5-Chloro-2,4-disulfamoylaniline 5-CHLORO-2,4-BIS(SULFONAMIDE)ANILINE Chloraminophenamide 5(3)-Chloroaniline-2,4(4,6)-disulfonamide 5-Chloro-2,4-bis(sulfonamide)aniline Hydrochlorothiazide IMpurity-B(EP) Hydrochlorothiazide IMpurity B (4-AMino-6-chlorobenzene-1,3-disulphonaMide, SalaMide) 1,3-Disulfonamide, 4-amino-6-chlorobenzene- m-Benzenedisulfonamide, 4-am m-Benzenedisulfonamide, 4-amino-6-chloro- (8CI) Salmid Fine sulfonamides 4-Amino-6-chlorobenzene-1,3-disulfonamide≥?99.0% Essence of sulfanilamide 3-disulfonamide 4-Amino-6-chlorobenzene-1 Benzothiadiazine USP RC A Compound Amiloride Hydrochloride Tablets Impurity Ⅰ:4-Amino-6-chlorobenzene-1,3-disulfonamide 3-Chloro-4,6-disulfamoylaniline 4-AMINO-6-CHLOROBENZENE-1,3-DISULFONAMIDE 4-AMINO-6-CHLORO-BENZENE-1,3-DISULFONIC ACID DIAMIDE 5(3)-CHLOROANILINE-2,4(4,6)-DISULFONAMIDE 4-Amino-6-Chloro-1,3-Benzendisulfonamide 4-Amino-6-Chloro-1,3-Benzenedisufonamide 1-AMINO-3-CHLORO-4,6-BENZENE- DISULFONAMIDE Chloroaminophenamide Idorese 3-Chloro-4,6-disulfamylaniline 4-Amino-6-chlorobenzene-1,3-bissulfonamide 4-Chloro-6-aminobenzene-1,3-disulfonamide 4-azanyl-6-chloro-benzene-1,3-disulfonamide 4-Amino-6-chloro-1,3-benzenedisulfonamide,3-Chloroaniline-4,6-disulfonamide, 4-Amino-6-chlorobenzene-1,3-disulfonamide Chloruminophenamide 1,3-Benzenedisulfonamide, 4-amino-6-chloro- 3-chloroaniline-4,6-disulfonamide 5-CHLORO-2,4-DISULFAMYLANILINE 4-AMINO-6-CHLORO-1,3-BENZENEDISULFONAMIDE 99+% 3-benzenedisulfonaMide 4-AMino-6-chloro-1 4-AMino-6-chloro-M-benzenedisulfonaMide NSC 93772 4-AMINO-6-CHLORO-1,3-BENZENDISULFAMIDEHYDROCHLOROTHIAZIDE Benzothiadiazine Related Compound A (100 mg) (4-Amino-6-chloro-1,3-benzenedisulfonamide) 4-aMino-6-chlorobenzen-1,3-disulphonaMide(salaMide) 4-Amino-6-Chloro-1,2-Benzenedisulfonamide Benzothiadiazine impurity A 5-Chloroaniline 2, 4-disulfonamide 4-Amino-6-chlorobenzene-1,3-disulph Amino benzenedisulfonamide 4-Amino-6-chlorobenzene-1,3-disulfonamide ISO 9001：2015 REACH Althiazide Impurity A Benzothiadiazine Related Compound A (Hydrochlorothiazide EP Impurity B/ Hydrochlorothiazide Related Compound A/ Salamide/ Altizide EP Impurity A) Altizide EP Impurity A (Hydrochlorothiazide EP Impurity B/ Hydrochlorothiazide Related Compound A/ Benzothiadiazine Related Compound A/ Salamide ) Hydrochlorothiazide EP Impurity B/ Hydrochlorothiazide Related Compound A (Benzothiadiazine Related Compound A/ Salamide/ Altizide EP Impurity A) Benzothiadiazine Related Compound AQ: What is Benzothiadiazine Related Compound A Q: What is the CAS Number of Benzothiadiazine Related Compound A