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1-ETHYL-3-PYRROLIDINOL

CAS No.
30727-14-1
Chemical Name:
1-ETHYL-3-PYRROLIDINOL
Synonyms
N-Ethyl-3-hydroxypyrrolidine;NSC 88610;Ethylpyrrolidinol;1-ethyl-3-pyrrolidino;1-ETHYL-3-PYRROLIDINOL;1-ethylpyrrolidin-3-ol;N- Ethyl-3-pyrrolidinol;3-Pyrrolidinol, 1-ethyl-;1-Ethyl-3-pyrrolidinol>1-ETHYL-3-PYRROLIDINOL 95+%
CBNumber:
CB9364778
Molecular Formula:
C6H13NO
Molecular Weight:
115.17
MDL Number:
MFCD00003179
MOL File:
30727-14-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 05:51:07
Product description Number Pack Size Price
1-Ethyl-3-pyrrolidinol 97% E47352 5g $422
1-Ethyl-3-pyrrolidinol >95.0%(GC)(T) E0425 10mL $73
1-Ethyl-3-pyrrolidinol FBA72714 25g $625
1-Ethyl-3-pyrrolidinol >98% OR920330 1g $21
1-Ethyl-3-pyrrolidinol >98% OR920330 5g $47
More product size

1-ETHYL-3-PYRROLIDINOL Properties

Boiling point 59-61 °C1 mm Hg(lit.)
Density 0.967 g/mL at 25 °C(lit.)
refractive index n20/D 1.467(lit.)
Flash point 165 °F
storage temp. Sealed in dry,Room Temperature
form clear liquid
pka 14.83±0.20(Predicted)
color Colorless to Brown
InChI 1S/C6H13NO/c1-2-7-4-3-6(8)5-7/h6,8H,2-5H2,1H3
InChIKey IDBNECMSCRAUNU-UHFFFAOYSA-N
SMILES CCN1CCC(O)C1
CAS DataBase Reference 30727-14-1(CAS DataBase Reference)
EWG's Food Scores 1
UNSPSC Code 12352100

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H227-H315-H319-H335
Precautionary statements  P261-P305+P351+P338-P210-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P370+P378-P403+P235-P501
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36/37/39
WGK Germany  3
RTECS  UY5685500
HS Code  2933998090
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
Toxicity mouse,LD50,intravenous,180mg/kg (180mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#02177,
NFPA 704
2
2 0

1-ETHYL-3-PYRROLIDINOL price More Price(57)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich E47352 1-Ethyl-3-pyrrolidinol 97% 30727-14-1 5g $422 2023-01-07 Buy
TCI Chemical E0425 1-Ethyl-3-pyrrolidinol >95.0%(GC)(T) 30727-14-1 10mL $73 2026-04-30 Buy
Biosynth FBA72714 1-Ethyl-3-pyrrolidinol 30727-14-1 25g $625 2026-06-04 Buy
Apolloscientific OR920330 1-Ethyl-3-pyrrolidinol >98% 30727-14-1 1g $21 2026-06-04 Buy
Apolloscientific OR920330 1-Ethyl-3-pyrrolidinol >98% 30727-14-1 5g $47 2026-06-04 Buy
Product number Packaging Price Buy
E47352 5g $422 Buy
E0425 10mL $73 Buy
FBA72714 25g $625 Buy
OR920330 1g $21 Buy
OR920330 5g $47 Buy

1-ETHYL-3-PYRROLIDINOL Chemical Properties,Uses,Production

Synthesis

1,4-DICHLORO-2-BUTANOL

2419-74-1

Ethylamine

75-04-7

1-ETHYL-3-PYRROLIDINOL

30727-14-1

The present embodiment is a method for the preparation of 1-ethyl-3-pyrrolidinol, which was carried out as follows: 250 g of 40 wt% aqueous ethylamine solution was added to a 500 mL four-necked flask, cooled to 10 °C, and placed in an ice-water bath. Under stirring conditions, 102 g of 1,4-dichloro-2-butanol was added dropwise, and the temperature was controlled to be about 15 °C. After the dropwise addition was completed in about 15 min, the reaction system was transferred to a 500 mL autoclave, sealed, evacuated to a pressure of 1.0±0.1 MPa, heated to 120±2°C, stirred and reacted for about 10 h. The reaction was monitored by GC until the raw material disappeared. After the reaction was completed, cooled to room temperature, discharged the reaction material, added 110g of sodium hydroxide in batches, taking care to control the temperature below 50°C to release ethylamine gas and precipitate a white solid, and continued stirring for 1h. After filtration, the filtrate was layered, the upper organic phase was taken, 100mL of ethanol and 18g of anhydrous magnesium sulfate were added, and stirred for 2~3h. Filtered again, and the filtrate was concentrated under vacuum to obtain a yellow transparent The filtrate was again filtered and concentrated under vacuum to obtain a yellow transparent oily liquid, and finally 46.7 g of colorless and transparent 1-ethyl-3-pyrrolidinol was obtained by vacuum distillation with a yield of 64.8% and a purity of 99.3% (HPLC).

References

[1] Patent: CN106631956, 2017, A. Location in patent: Paragraph 0022; 0023; 0024; 0025; 0026; 0027

1-ETHYL-3-PYRROLIDINOL Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 116)Suppliers
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career henan chemical co
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View Lastest Price from 1-ETHYL-3-PYRROLIDINOL manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-ETHYL-3-PYRROLIDINOL pictures 2019-09-02 1-ETHYL-3-PYRROLIDINOL
30727-14-1
$1.00 1KG ≥98% 200kg Career Henan Chemical Co
NSC 88610 1-ethyl-3-hydroxy-terthydropyrrolo 1-ethyl-3-pyrrolidino 3-Pyrrolidinol, 1-ethyl- 1-ETHYL-3-PYRROLIDINOL 1-ETHYL-3-HYDROXYPYRROLIDINE N-Ethylpyrrolidin-3-ol (racemat) 1-ETHYL-3-PYRROLIDINOL 95+% Ethylpyrrolidinol 1-ethylpyrrolidin-3-ol N- Ethyl-3-pyrrolidinol 1-Ethyl-3-pyrrolidinol> N-Ethyl-3-hydroxypyrrolidine 30727-14-1 ALCOHOL Heterocyclic Building Blocks Pyrrolidines Building Blocks Heterocycles Building Blocks Heterocyclic Building Blocks Pyrrolidines