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ChemicalBook >> CAS DataBase List >>(Met(o)27)-glucagon (1-29) (human, bovine, porcine)

(Met(o)27)-glucagon (1-29) (human, bovine, porcine)

(Met(o)27)-glucagon (1-29) (human, bovine, porcine) Structure
(Met(o)27)-glucagon (1-29) (human, bovine, porcine) structure
CAS No.
75217-63-9
Chemical Name:
(Met(o)27)-glucagon (1-29) (human, bovine, porcine)
Synonyms
GLUCAGON PEPTIDE;GLUCAGON, HUMAN;GLUCAGON, HUMAN/RAT;GLUCAGON (1-29), HUMAN;glucagon, Met-sulfoxide(27)-;HSQGTFTSDYSKYLDSRRAQDFVQWLMNT;GLUCAGON HUMAN, BOVINE, PORCINE;GLUCAGON (1-29), BOVINE, HUMAN, PORCINE;GLUCAGON (1-29) (HUMAN, BOVINE, PORCINE);Glucagon (swine), 27-(L-methionine S-oxide)-
CBNumber:
CB9401440
Molecular Formula:
C153H225N43O50S
Molecular Weight:
3498.75
MDL Number:
MFCD08458617
MOL File:
75217-63-9.mol
TDS File:
TDS
Last updated:2026-09-12 18:56:28
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(Met(o)27)-glucagon (1-29) (human, bovine, porcine) Properties

Density 1.54±0.1 g/cm3(Predicted)
storage temp. -20°C
Sequence His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-{Met(O)}-Asn-Thr

(Met(o)27)-glucagon (1-29) (human, bovine, porcine) price More Price(49)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 05-23-2700 Glucagon, Human Synthetic, human glucagon. Peptide hormone secreted by pancreatic α-cells. An important hyperglycemic agent. 75217-63-9 .1mg $138 2025-07-31 Buy
Sigma-Aldrich 05-23-2700 Glucagon, Human Synthetic, human glucagon. Peptide hormone secreted by pancreatic α-cells. An important hyperglycemic agent. 75217-63-9 .5mg $275 2025-07-31 Buy
Biosynth HOR-286 Glucagon, human 4mg $714.6 2026-06-04 Buy
Biosynth HOR-286 Glucagon, human 10mg $1020.9 2026-06-04 Buy
Biosynth HOR-286 Glucagon, human 50mg $1837.5 2026-06-04 Buy
Product number Packaging Price Buy
05-23-2700 .1mg $138 Buy
05-23-2700 .5mg $275 Buy
HOR-286 4mg $714.6 Buy
HOR-286 10mg $1020.9 Buy
HOR-286 50mg $1837.5 Buy

(Met(o)27)-glucagon (1-29) (human, bovine, porcine) Chemical Properties, Uses, Production

Uses

(Met(O)27)-Glucagon (1-29) (human, rat, porcine) is a modified glucagon. (Met(O)27)-Glucagon (1-29) (human, rat, porcine) has the same maximum glucose-synthesizing activity in rat hepatocytes as native glucagon, but it is less potent, suggesting a crucial role of methionine in the binding of glucagon to its hepatic receptor[1].

Description

Glucagon Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 29 amino acids and having a molecular mass of 3483 Dalton.
The Glucagon is purified by proprietary chromatographic techniques.

Source

Escherichia Coli

Background

Glucagon is an important hormone involved in carbohydrate metabolism. The hormone is synthesized and secreted from alpha cells (a-cells) of the islets of Langerhans, which are located in the endocrine portion of the pancreas. Glucagon is released when the glucose level in the blood is low (hypoglycemia), causing the liver to convert stored glycogen into glucose and release it into the bloodstream. The action of glucagon is thus opposite to that of insulin, which instructs the body's cells to take in glucose from the blood in times of satiation.
Glucagon is beneficial for the culture of some cell types. It has been used in some biochemical regulation studies of glycogenolysis in hepatocytes. It has been also been found to induce DNA replication in primary cultures of adult rat hepatocytes when used in combinations with EGF and Insulin. Glucagon increases the blood glucose concentration by promoting rapid breakdown of liver glycogen, and also acts to relax smooth muscle such as the gastrointestinal tract.

References

[1] Nooijen WJ, et al. Immunogenicity and bioactivity of glucagon, modified at methionine-27. Horm Metab Res. 1979 Aug;11(8):459-63. DOI:10.1055/s-0028-1092761

(Met(o)27)-glucagon (1-29) (human, bovine, porcine) Preparation Products And Raw materials

Raw materials

Preparation Products

(Met(o)27)-glucagon (1-29) (human, bovine, porcine) Suppliers

Global Suppliers ( 107)
Supplier Tel Email Country ProdList Advantage
GL Biochem (Shanghai) Ltd 21-61263452 13641803416 ymbetter@glbiochem.com China 9981 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15350 60
Cellmano Biotech Limited 0551-65326643 18156095617 info@cellmano.com China 1010 55
Wuxi Zhongkun Biochemical Technology Co., Ltd. 0510-85629785 18013409632; sales@reading-chemicals.com China 15165 58
Hangzhou Peptide Biochem Co.,Ltd 0571-89197072; 18668118770 linda@peptide-china.com China 233 56
Creative Peptides info@creative-peptides.com United States 6083 56
Shanghai SuperLan Chemcial Technique Centre 0-2022843681 15618226720 chaolaichem@foxmail.com China 9996 58
Nanjing Leon Biological Technology Co., Ltd. 025-84523390 -127; 17705183659 sales@njleonbiotech.com China 5501 55
Nanjing Peptide Biotech Ltd. 025-58361106-805 15951641583 zhao.xu@njpeptide.com China 9976 55
Supplier Advantage
GL Biochem (Shanghai) Ltd 64
Shanghai Hanhong Scientific Co.,Ltd. 64
Chemsky (shanghai) International Co.,Ltd 60
Cellmano Biotech Limited 55
Wuxi Zhongkun Biochemical Technology Co., Ltd. 58
Hangzhou Peptide Biochem Co.,Ltd 56
Creative Peptides 56
Shanghai SuperLan Chemcial Technique Centre 58
Nanjing Leon Biological Technology Co., Ltd. 55
Nanjing Peptide Biotech Ltd. 55

75217-63-9 ((Met(o)27)-glucagon (1-29) (human, bovine, porcine)) Related Search:

L-Threonine, L-histidyl-L-seryl-L-glutaminylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-α-aspartyl-2-methylalanyl-L-alanyl-L-arginyl-L-alanyl-L-α-glutamyl-L-α-glutamyl-L-phenylalanyl-L-valyl-L-lysyl-L-tryptophyl-L-leucyl-L-α-glutamy... glucagon-like peptide 1 GLP-1（Glucagon-like peptide-1）(7-36) GIP (HUMAN) GLUCAGON-37 (HUMAN, MOUSE, RAT)
GLUCAGON-LIKE PEPTIDE I FRAGMENT 7-36 AMIDE HUMAN GLP-1 Uric acid Glucagon Glucagon hydrochloride(human)
H-His-Asp-Glu-Phe-Glu-Arg-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2 H-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH (Met(o)27)-glucagon (1-29) (human, bovine, porcine) Mazdutide Utreglutide
H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-TyrLeu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-LeuVal-Lys-Gly-Arg-Lys(biotinyl)-NH2

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glucagon, Met-sulfoxide(27)- GLUCAGON, HUMAN GLUCAGON HUMAN, BOVINE, PORCINE GLUCAGON, HUMAN/RAT GLUCAGON (1-29), BOVINE, HUMAN, PORCINE GLUCAGON (1-29), HUMAN GLUCAGON (1-29) (HUMAN, BOVINE, PORCINE) HSQGTFTSDYSKYLDSRRAQDFVQWLMNT H-HIS-SER-GLN-GLY-THR-PHE-THR-SER-ASP-TYR-SER-LYS-TYR-LEU-ASP-SER-ARG-ARG-ALA-GLN-ASP-PHE-VAL-GLN-TRP-LEU-MET(O)-ASN-THR-OH HIS-SER-GLN-GLY-THR-PHE-THR-SER-ASP-TYR-SER-LYS-TYR-LEU-ASP-SER-ARG-ARG-ALA-GLN-ASP-PHE-VAL-GLN-TRP-LEU-MET-ASN-THR (Met(O)27)-Glucagon (1-29) (human, rat, porcine) ALA-GLN-ASP-PHE-VAL-GLN-TRP-LEU-MET-ASN-THR: AQDFVQWLMNT Glucagon (swine), 27-(L-methionine S-oxide)- (Met(O)27)-Glucagon (1-29) (human, rat, porcine) trifluoroacetate salt (MET(O)27)-GLUCAGON (1-29) (HUMAN, BOVINE, PORCINE) USP/EP/BP Glucagon(swine),27-[(2S)-2-amino-4-(methylsulfinyl)butanoic acid]- (Met(O)??)-Glucagon (1-29) (human, rat, porcine) trifluoroacetate salt Glucagon Impurity 8 Tetratrifluoroacetate Met(O) 27 Glucagon) (Met(O))-Glucagon (1-29)(Human, bovine, porcine) GLUCAGON PEPTIDE (Met(o)27)-glucagon (1-29) (human, bovine, porcine) 75217-63-9 C153H225N43O49S1 C153H225N43O50S Other Protein/Peptide Hormones Cytokines, Growth Factors and Hormones Hormones BioChemical Cell Biology Cell Signaling and Neuroscience Peptide