FLONICAMID
- CAS No.
- 158062-67-0
- Chemical Name:
- FLONICAMID
- Synonyms
- Aria;Flonicamid [iso];flonicamid、flunicotamid;flonicamid 96% 158062-67-0;N-(cyanoMethyl)-4-(trifluoroMethyl)nicotinaMide;N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide;3-Pyridinecarboxamide, N-(cyanomethyl)-4-(trifluoromethyl)-;F 1785;iki-220;flonicami
- CBNumber:
- CB9506020
- Molecular Formula:
- C9H6F3N3O
- Molecular Weight:
- 229.16
- MDL Number:
- MFCD07364026
- MOL File:
- 158062-67-0.mol
- MSDS File:
- SDS
| Melting point | 157.5° |
|---|---|
| Boiling point | 406.6±45.0 °C(Predicted) |
| Density | 1.377±0.06 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | DMSO (Slightly), Methanol (Slightly), Ethanol (Slightly, Heated) |
| pka | 10.99±0.46(Predicted) |
| form | Solid |
| color | Light Beige to Beige |
| Henry's Law Constant | 2.4×107 mol/(m3Pa) at 25℃, HSDB (2015) |
| Major Application |
agriculture environmental |
| InChI | InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16) |
| InChIKey | RLQJEEJISHYWON-UHFFFAOYSA-N |
| SMILES | C1=NC=CC(C(F)(F)F)=C1C(NCC#N)=O |
| LogP | 0.840 (est) |
| EWG's Food Scores | 1 |
| FDA UNII | 9500W2Z53J |
| EPA Substance Registry System | Flonicamid (158062-67-0) |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312+P330-P501 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| WGK Germany | 2 | |||||||||
| HS Code | 29333990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral | |||||||||
| Hazardous Substances Data | 158062-67-0(Hazardous Substances Data) | |||||||||
| Toxicity | LD50 in male, female rats (mg/kg): 884, 1768 orally; in rats (mg/kg): >5000 dermally; in rats (mg/m3): >4900 by inhalation; LC50 in carp, rainbow trout (mg/l): >100, >91.9 (Morita) | |||||||||
| NFPA 704 |
|
FLONICAMID price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 32509 | Flonicamid PESTANAL | 158062-67-0 | 25mg | $156 | 2026-04-30 | Buy |
| TCI Chemical | F1309 | Flonicamid | 158062-67-0 | 250MG | $99 | 2026-04-30 | Buy |
| TCI Chemical | F1309 | Flonicamid | 158062-67-0 | 1G | $247 | 2026-04-30 | Buy |
| Cayman Chemical | 25608 | Flonicamid ≥98% | 158062-67-0 | 5mg | $103 | 2026-04-30 | Buy |
| Cayman Chemical | 25608 | Flonicamid ≥98% | 158062-67-0 | 10mg | $194 | 2026-04-30 | Buy |
FLONICAMID Chemical Properties, Uses, Production
Description
Flonicamid is a pyridinecarboxamide insecticide. It inhibits the brown planthopper (N. lugens) inward-rectifying potassium channel Kir1 (IC50 = 0.64 μM). Flonicamid (100 μg/ml) inhibits aphid (M. persicae) salivation and sap ingestion during feeding on Japanese radish leaves. It induces toxicity in the aphid species A. gossypii, R. padi, S. graminum, and L. erysimi (LC50s = 0.64, 0.74, 0.78, and 2.01 μg/ml, respectively) and rats (LD50 = ≥844 mg/kg). Formulations containing flonicamid have been used for the control of pest insects in agriculture.
Uses
Flonicamid is an novel insecticide with rapid inhibitory effect against aphid feeding.
Uses
Insecticide.
Uses
Flonicamid is a novel insecticide with rapid inhibitory effect against aphid feeding. Useful in cannabis testing kits as a component of pesticide mixes (P698240).
Definition
ChEBI: A pyridinecarboxamide that is nicotinamide substituted by a trifluoromethyl group at position 4 and a cyanomethyl group at the carbamoyl nitrogen atom.
Application
With foliar spray application at the rates of 50-100 g a.i./ha, onicamid exhibits excellent aphicidal activity and also shows good insecticidal activity against other sucking insect pests such as thrips, white ies, planthoppers, leafhoppers, plant bugs, and mealybugs in fruit trees, cereals, rice, potatoes, cotton, vegetables and ornamentals. Flonicamid soil applications also provide control of the foliar pests mentioned above.
Definition
Flonicamid is a chordotonal modulator and novel systemic insecticide that has been used frequently for controlling a broad range of insect pests. The risk of flonicamid resistance was assessed through laboratory selection and determining inheritance pattern and cross-resistance potential to five insecticides in house fly, Musca domestica L. Very low to high flonicamid resistance in M. domestica populations was found compared with the susceptible strain (SS).
Synthesis
Flonicamid is commercially produced through a multi-step chemical synthesis that begins with the preparation of 4-trifluoromethylnicotinic acid, which serves as the core structural component. This acid is converted into its acid chloride form using reagents like thionyl chloride, enabling it to react with aminoacetonitrile hydrochloride in the presence of a base and a phase-transfer catalyst. The resulting intermediate amide is then treated with aqueous sodium carbonate to yield flonicamid, a compound with high purity and yield.
Mode of action
Flonicamid rapidly inhibits the feeding behavior of aphids, and has better action through ingestion than by contact. Its mode of action is different from other insecticides such as neonicotinoids, pymetrozine and pyri uquinazon. Flonicamid belongs to IRAC Group 29 and is the only insecticide in this class.
References
[1] MIAOMIAO REN . Block of Kir channels by flonicamid disrupts salivary and renal excretion of insect pests[J]. Insect Biochemistry and Molecular Biology, 2018, 99: Pages 17-26. DOI: 10.1016/j.ibmb.2018.05.007
[2] MASAYUKI MORITA. Flonicamid, a novel insecticide with a rapid inhibitory effect on aphid feeding[J]. Pest Management Science, 2007, 63 10: 969-973. DOI: 10.1002/ps.1423
[3] M. MORITA N A T Yoneda. Research and development of a novel insecticide, flonicamid[J]. Journal of Pesticide Science, 2014, 39 1: 179-180. DOI: 10.1584/jpestics.j14-05
Pesticide Type
Insecticide
FLONICAMID Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Dueling International Trade Co. LTD | 18032116176 | 399549586@qq.com | China | 1178 | 58 |
| Huaibei Longxi Biotechnology Co., Ltd. | 18956118929 | 18956118929@163.com | China | 487 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| TargetMol Chemicals Inc. | 021-021-33632979 15002134094 | marketing@targetmol.com | China | 7993 | 58 |
| TianJin Alta Scientific Co., Ltd. | 022-65378550-8551 | contact@altascientific.com | China | 2772 | 58 |
| Quality Control Solutions Ltd. | 0755-66853366 13670046396 | orders@qcsrm.com | China | 18188 | 56 |
| Shanghai Macklin Biochemical Co.,Ltd. | 15221275939 15221275939 | shenlinxing@macklin.cn | China | 15775 | 55 |
| Hubei Jusheng Technology Co.,Ltd | 027-59599241 18871490274 | 1400878000@qq.com | China | 9506 | 58 |
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- Jan 21,2022
View Latest Price from FLONICAMID manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-14 | Flonizamid
158062-67-0
|
100kg | 98 | 10000 | Qingdao Trust Agri Chemical Co.,Ltd | ||
 |
2026-06-30 | FLONICAMID
158062-67-0
|
1kg | 98% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2026-05-11 | Flonicamid
158062-67-0
|
99.30% | 10g | TargetMol Chemicals Inc. |
-
- Flonizamid
158062-67-0
- $0.00
- 98
- Qingdao Trust Agri Chemical Co.,Ltd
-
- FLONICAMID
158062-67-0
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- Flonicamid
158062-67-0
- $0.00
- 99.30%
- TargetMol Chemicals Inc.
