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1,3,5-Trifluorobenzene

1,3,5-Trifluorobenzene Structure
1,3,5-Trifluorobenzene structure
CAS No.
372-38-3
Chemical Name:
1,3,5-Trifluorobenzene
Synonyms
1,3,5-Trifluorobenze;1,3,5-TrifL;Trifluorobenzene3;sym-Trifluorobenzene;1,3,5-Trifluorbenzol;1,3,5-TRIFLUOROBENZENE;1,3,5-TRIFLUOTOBENZENE;Benzene, 1,3,5-trifluoro-;1,3,5-Trifluorobenzene 98%;1,3,5-trifluorobenzoic acid
CBNumber:
CB9690716
Molecular Formula:
C6H3F3
Molecular Weight:
132.08
MDL Number:
MFCD00000333
MOL File:
372-38-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 05:43:45
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1,3,5-Trifluorobenzene Properties

Melting point -5.5 °C (lit.)
Boiling point 75-76 °C (lit.)
Density 1.277 g/mL at 25 °C (lit.)
refractive index n20/D 1.414(lit.)
Flash point 19 °F
storage temp. Flammables area
form clear liquid
Specific Gravity 1.277
color Colorless to Almost colorless
Water Solubility Insoluble in water.
BRN 1906457
InChI InChI=1S/C6H3F3/c7-4-1-5(8)3-6(9)2-4/h1-3H
InChIKey JXUKFFRPLNTYIV-UHFFFAOYSA-N
SMILES C1(F)=CC(F)=CC(F)=C1
CAS DataBase Reference 372-38-3(CAS DataBase Reference)
FDA UNII BN94C411F8
NIST Chemistry Reference 1,3,5-Trifluorobenzene(372-38-3)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Exclamation Mark (GHS07)
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H315-H319-H335
Precautionary statements  P210-P302+P352-P305+P351+P338
target organs Respiratory system
PPE Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  F,Xi
Risk Statements  11-36/37/38
Safety Statements  16-26-36-7-33-29-7/9
RIDADR  UN 1993 3/PG 2
WGK Germany  2
Hazard Note  Flammable
HazardClass  3
PackingGroup  II
HS Code  29039990
Storage Class 3 - Flammable liquids
Hazard Classifications Eye Irrit. 2
Flam. Liq. 2
Skin Irrit. 2
STOT SE 3
Limited Quantities 1.0 L (0.3 gallon) (liquid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)
NFPA 704
3
2 0

1,3,5-Trifluorobenzene price More Price(42)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 196851 1,3,5-Trifluorobenzene 97% 372-38-3 5g $121 2026-04-30 Buy
Sigma-Aldrich 196851 1,3,5-Trifluorobenzene 97% 372-38-3 25g $192 2026-04-30 Buy
TCI Chemical T1039 1,3,5-Trifluorobenzene >98.0%(GC) 372-38-3 5g $83 2026-04-30 Buy
TCI Chemical T1039 1,3,5-Trifluorobenzene >98.0%(GC) 372-38-3 25g $247 2026-04-30 Buy
Biosynth FT70543 1,3,5-Trifluorobenzene 372-38-3 25g $150 2026-06-04 Buy
Product number Packaging Price Buy
196851 5g $121 Buy
196851 25g $192 Buy
T1039 5g $83 Buy
T1039 25g $247 Buy
FT70543 25g $150 Buy

1,3,5-Trifluorobenzene Chemical Properties,Uses,Production

Synthesis

In a reaction flask, solvent, anhydrous potassium fluoride, a phase transfer catalyst, and crude 1,3,5-trichlorobenzene were added. The mixture was heated to reflux and reacted for 6-14 hours. After the reaction was complete, the solvent was removed by vacuum distillation, and the residue was subjected to steam distillation with water. The distillate was extracted with petroleum ether (60-90℃), and after removing the petroleum ether by rotary evaporation, the target compound 1,3,5-trifluorobenzene was collected by vacuum distillation.

Synthetic reaction formula of 1,3,5-trifluorobenzene

Figure 1,3,5-trifluorobenzene synthesis reaction formula

Chemical Properties

CLEAR COLOURLESS LIQUID

Uses

1,3,5-Trifluorobenzene was used in the synthesis of (-)-epicatechin and its 3-O-gallate. It is also used as an intermediate in organic chemical synthesis.

Uses

1,3,5-Trifluorobenzene was used in the synthesis of ()-epicatechin and its 3-O-gallate.

General Description

Rotational Raman spectra of 1,3,5-trifluorobenzene has been studied under high resolution using a single mode argon laser as the exciting source. Proton and fluorine magnetic resonance spectra of 1,3,5-trifluorobenzene in a nematic liquid crystal has been analyzed.

1,3,5-Trifluorobenzene synthesis

108-70-3
372-38-3
1435-43-4
Synthesis of 1,3,5-Trifluorobenzene from 1,3,5-Trichlorobenzene

1,3,5-Trifluorobenzene Preparation Products And Raw materials

Raw materials

1,2,4,5-Tetrafluorobenzene 1,3,5-Trichloro-2,4,6-trifluorobenzene 1,3-DICHLORO-2,4,6-TRIFLUOROBENZENE 2,4,6-Trifluorochlorobenzene 3,5-Difluoronitrobenzene
3,5-Difluorochlorobenzene 2,4,6-Trifluorophenylboronic acid Pentafluorobenzene 1,2,3,4-Tetrafluorobenzene 1,3,5-Trichlorobenzene
3,5-Dichlorofluorobenzene

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Preparation Products

3,5-Difluorophenylacetic acid 2,4,6-Trifluorobenzoic acid 2,4,6-TRIFLUOROBENZENESULFONYL CHLORIDE 1-Bromo-2,4,6-trifluorobenzene 2,4,6-TRIFLUOROIODOBENZENE
1,3,5-Triphenylbenzene

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1,3,5-Trifluorobenzene Suppliers

Global( 401)Suppliers
Supplier Tel Email Country ProdList Advantage
Qi-Chem Co., Ltd. 0411-88165951 13601035838 marketing@qi-chem.com China 167 58
SHANG FLUORO 021-65170832 15601903708 qinba_1@163.com China 401 60
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Beijing dtftchem Technology Co., Ltd. 010-60275820 13031183356 elainezt@sina.com China 1386 62
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Supplier Advantage
Qi-Chem Co., Ltd. 58
SHANG FLUORO 60
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
Beijing dtftchem Technology Co., Ltd. 62
Energy Chemical 61
Wuhan Chemwish Technology Co., Ltd 56
Capot Chemical Co., Ltd 66

Related articles

  • What is 1,3,5-Trifluorobenzene?
  • Using a single-mode argon laser as the excitation light source, the rotating Raman spectrum of 1,3,5-trifluorobenzene was stud....
  • Jan 16,2020

View Lastest Price from 1,3,5-Trifluorobenzene manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1,3,5-Trifluorobenzene pictures 2026-09-02 1,3,5-Trifluorobenzene
372-38-3
 $1.00-100.00 1KG 99% Henan Fengda Chemical Co., Ltd
1,3,5-Trifluorobenzene pictures 2025-04-04 1,3,5-Trifluorobenzene
372-38-3
 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
1,3,5-Trifluorobenzene pictures 2019-07-06 1,3,5-Trifluorobenzene
372-38-3
 $1.00 1kg 99% Career Henan Chemical Co

1,3,5-Trifluorobenzene Spectrum

1,3,5-Trifluorobenzene(372-38-3)MS1,3,5-Trifluorobenzene(372-38-3)1HNMR1,3,5-Trifluorobenzene(372-38-3)IR11,3,5-Trifluorobenzene(372-38-3)Raman

372-38-3(1,3,5-Trifluorobenzene)Related Search:

3,4,5-Trifluorophenol 4-Fluorobenzaldehyde 2,4,5-Trifluorobenzoic acid Transfluthrin Florfenicol
Trifluoroacetophenone tetrafluorobenzene 2',3',4',5',6'-PENTAFLUOROACETOPHENONE Pentafluorobenzene Decafluorobiphenyl
DIPHENYL(PENTAFLUOROPHENYL)PHOSPHINE 1,2,3,5-Tetrafluorobenzene hexafluorobenzene 2,4,5-Trifluorophenylacetic acid α-Bromo-2,3,4,5,6-pentafluorotoluene
2,3,4,5,6-Pentafluorobenzophenone Decafluorobenzhydrol 2,3,4,5,6-Pentafluorostyrene

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Benzene, 1,3,5-trifluoro- sym-Trifluorobenzene 1,3,5-TRIFLUOROBENZENE 1,3,5-Trifluorobenzene 98% 1,3,5-TRIFLUOTOBENZENE 1,3,5-Trifluorbenzol 1,3,5-trifluorobenzoic acid Trifluorobenzene3 1,3,5-Trifluorobenzene, 98+% 1,3,5-Trifluorobenze 1,3,5-Trifluorobenzene, 98+% 10ML 1,3,5-trifluorobenzene cation 1-(4-methylphenyl)sulfonyl-3-(1-phenylpropan-2-yl)urea 1,3,5-TrifL 1,3,5-Trifluorobenzene ISO 9001：2015 REACH 372-38-3 51-62-2 Aryl Organic Building Blocks Halogenated Hydrocarbons Building Blocks C6 Aryl Halogenated Hydrocarbons Aromatic Hydrocarbons (substituted) & Derivatives Fluorobenzene Miscellaneous bc0001 OLED C6