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1-(Tetrahydro-2H-pyran-4-yl)ethanone

1-(Tetrahydro-2H-pyran-4-yl)ethanone Structure
1-(Tetrahydro-2H-pyran-4-yl)ethanone structure
CAS No.
137052-08-5
Chemical Name:
1-(Tetrahydro-2H-pyran-4-yl)ethanone
Synonyms
ACP;1-(tetrahydro-2H-pyran-4-yl)ethan-1-one;4-Acetyltetrahydropyran;FASN2A;NDUFAB1;MGC65095;EOS-61643;1-(oxan-4-yL;1-(oxan-4-yl)ethanone;1-(oxan-4-yl)ethan-1-one
CBNumber:
CB9794612
Molecular Formula:
C7H12O2
Molecular Weight:
128.17
MDL Number:
MFCD08704647
MOL File:
137052-08-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 06:11:58
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1-(Tetrahydro-2H-pyran-4-yl)ethanone Properties

Boiling point 90-94℃/15mm
Density 1.024
refractive index 1.4530
storage temp. -20°C
form Liquid
color Colorless to pale yellow
InChI InChI=1S/C7H12O2/c1-6(8)7-2-4-9-5-3-7/h7H,2-5H2,1H3
InChIKey VNMXIOWPBADSIC-UHFFFAOYSA-N
SMILES C(=O)(C1CCOCC1)C

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xn
Risk Statements  42-36
Safety Statements  22-45-26
HS Code  2933998090
NFPA 704
1
2 0

1-(Tetrahydro-2H-pyran-4-yl)ethanone price More Price(72)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 325419 NDUFAB1 Purifiedbyimmunoaffinitychromatography. 50ul $509 2026-06-03 Buy
Usbiological 290674 1-(Tetrahydro-2H-pyran-4-yl)ethanone Asreported 137052-08-5 100mg $333 2026-06-03 Buy
Usbiological 325419 NDUFAB1 Purifiedbyimmunoaffinitychromatography. 100ul $708 2026-06-03 Buy
Usbiological 290674 1-(Tetrahydro-2H-pyran-4-yl)ethanone Asreported 137052-08-5 250mg $460 2026-06-03 Buy
Usbiological 325418 NDUFAB1 Purifiedbyimmunoaffinitychromatography. 50ul $509 2026-06-03 Buy
Product number Packaging Price Buy
325419 50ul $509 Buy
290674 100mg $333 Buy
325419 100ul $708 Buy
290674 250mg $460 Buy
325418 50ul $509 Buy

1-(Tetrahydro-2H-pyran-4-yl)ethanone Chemical Properties, Uses, Production

Uses

1-(Tetrahydro-2H-pyran-4-yl)ethanone is mainly used as an intermediate in organic synthesis and medicinal chemistry, and can be used in the synthesis of cell biology detection reagents. In organic synthetic transformations, the keto carbonyl group in 1-(Tetrahydro-2H-pyran-4-yl)ethanone can be reacted with Wittig's reagent to prepare a variety of polysubstituted olefinic compounds, and in addition, the keto carbonyl group can be reduced to a hydroxyl group by the corresponding reducing agent.

Synthesis

Ethyl 4-acetyl tetrahydro-2H-pyran-4-carboxylate

345216-96-8

1-(Tetrahydro-2H-pyran-4-yl)ethanone

137052-08-5

Example 1 (Synthesis of 4-acetyltetrahydropyran) In a 10 mL glass flask equipped with a stirring device, a thermometer and a reflux condenser, 0.38 g (2.0 mmol) of methyl 4-acetyltetrahydro-2H-pyran-4-carboxylate (synthesized according to the method of Reference Example 1) of 99% purity and 1.08 mL (10 mmol) of 9 mol/L sulfuric acid were added. The reaction mixture was heated to 120°C under stirring and the reaction lasted for 1.5 hours. Upon completion of the reaction, the reaction mixture was analyzed by gas chromatography (internal standard method) and the formation of 0.25 g (yield: 96%) of 4-acetyltetrahydropyran was confirmed.

References

[1] Patent: EP1700852, 2006, A1. Location in patent: Page/Page column 7-8
[2] Patent: EP1700852, 2006, A1. Location in patent: Page/Page column 8
[3] Patent: WO2011/50016, 2011, A1. Location in patent: Page/Page column 35-36

1-(Tetrahydro-2H-pyran-4-yl)ethanone synthesis

156353-01-4
75-16-1
137052-08-5
Synthesis of 1-(Tetrahydro-2H-pyran-4-yl)ethanone from N-Methoxy-N-Methyltetrahydropyran-4-carboxaMide and Methylmagnesium Bromide

1-(Tetrahydro-2H-pyran-4-yl)ethanone Preparation Products And Raw materials

Raw materials

zinc methyl iodide Methyl tetrahydropyran-4-carboxylate N-Methoxy-N-Methyltetrahydropyran-4-carboxaMide Ethyl 4-acetyl tetrahydro-2H-pyran-4-carboxylate Tetrahydro-2H-pyran-4-carbonyl chloride
4-Cyanotetrahydro-4H-pyran Tetrahydro-2H-pyran-4-carboxylic acid Methylmagnesium Bromide

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Preparation Products

Ethanone, 2-bromo-1-(tetrahydro-2H-pyran-4-yl)- (9CI)

1-(Tetrahydro-2H-pyran-4-yl)ethanone Suppliers

Global Suppliers ( 208)
Supplier Tel Email Country ProdList Advantage
AstaTech(Chengdu) Biopharmaceutical Corp. 028-82666846 18080826311 sales@astatech.com.cn China 499 58
Chengdu Zhongde Jihua Pharmaceutical Technology Co., Ltd 15928014948; 15928014948 3438599507@qq.com China 97 58
Jinan Kabotang Biological Technology Co.,Ltd. 0531-61320525 15866703830 figo.gao@foxmail.com China 7601 58
BTC Pharmaceutical CO. Ltd +86-15716293042 15716293042 info@btcpharm.com China 822 55
Creasyn Finechem(Tianjin) Co., Ltd. 022-83946278 13820372920 sales@creasyn.com China 968 68
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Jia Xing Isenchem Co.,Ltd 0573-85285100 18627885956 isenchem@163.com China 9389 66
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16305 64
Shanghai Ennopharm Co., Ltd. +86 (21) 6435-5022 China 4263 65
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8663 57
Supplier Advantage
AstaTech(Chengdu) Biopharmaceutical Corp. 58
Chengdu Zhongde Jihua Pharmaceutical Technology Co., Ltd 58
Jinan Kabotang Biological Technology Co.,Ltd. 58
BTC Pharmaceutical CO. Ltd 55
Creasyn Finechem(Tianjin) Co., Ltd. 68
Energy Chemical 61
Jia Xing Isenchem Co.,Ltd 66
Nanjing Chemlin Chemical Co., Ltd 64
Shanghai Ennopharm Co., Ltd. 65
Shanghai Sunway Pharmaceutical Technology Co., Ltd 57

View Latest Price from 1-(Tetrahydro-2H-pyran-4-yl)ethanone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-(Tetrahydro-2H-pyran-4-yl)ethanone pictures 2026-09-17 1-(Tetrahydro-2H-pyran-4-yl)ethanone
137052-08-5
 1KG 97%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
1-(Tetrahydro-2H-pyran-4-yl)ethanone pictures 2023-03-29 1-(Tetrahydro-2H-pyran-4-yl)ethanone
137052-08-5
 1kg 98% 1000kg LY Global chemicals co.,ltd .
1-(Tetrahydro-2h-pyran-4-yl)ethanone pictures 2022-01-27 1-(Tetrahydro-2h-pyran-4-yl)ethanone
137052-08-5
 1KG 99.5% 100 tons Honest Joy Holdings Limited

1-(Tetrahydro-2H-pyran-4-yl)ethanone Spectrum

1-(Tetrahydro-2H-pyran-4-yl)ethanone(137052-08-5)1HNMR

137052-08-5 (1-(Tetrahydro-2H-pyran-4-yl)ethanone) Related Search:

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4-ACETYLTETRAHYDRO-4H-PYRAN 1-ACETOXY-3-CARBAMOYL,2,2,5,5-TETRAMETHYLPYRROLIDINE Ethanone, 1-(tetrahydro-2H-pyran-4-yl)- (9CI) Ethanone, 1-(tetrahydro-2H-pyran-4-yl) 1-(tetrahydro-2H-pyran-4-yl)ethanone 1-Tetrahydropyran-4-yl-ethanone 1-(Tetrahydro-2H-pyran-4-yl)ethan-1-one, 4-Acetyloxane 4-Acetyltetrahydro-2H-pyran 1-(oxan-4-yl)ethan-1-one FASN2A MGC65095 NDUFAB1 EOS-61643 1-(oxan-4-yl)ethanone 4-Acetyltetrahydro-2H-pyran 97% 1-(TETRAHYDRO-2H-PYRAN-4-YL)ETHANE -1-ONE 1-(oxan-4-yL 4-Acetyltetrahydropyran,97% 137052-08-5 1-(tetrahydro-2H-pyran-4-yl)ethan-1-one 4-Acetyltetrahydropyran ACP 137052-08-5 137502-08-5 ACETYLGROUP API