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1-(Tetrahydro-2H-pyran-4-yl)ethanone

CAS No.
137052-08-5
Chemical Name:
1-(Tetrahydro-2H-pyran-4-yl)ethanone
Synonyms
ACP;1-(tetrahydro-2H-pyran-4-yl)ethan-1-one;4-Acetyltetrahydropyran;FASN2A;NDUFAB1;MGC65095;EOS-61643;1-(oxan-4-yL;1-(oxan-4-yl)ethanone;1-(oxan-4-yl)ethan-1-one
CBNumber:
CB9794612
Molecular Formula:
C7H12O2
Molecular Weight:
128.17
MDL Number:
MFCD08704647
MOL File:
137052-08-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 06:11:58
Product description Number Pack Size Price
NDUFAB1 Purifiedbyimmunoaffinitychromatography. 325419 50ul $509
1-(Tetrahydro-2H-pyran-4-yl)ethanone Asreported 290674 100mg $333
NDUFAB1 Purifiedbyimmunoaffinitychromatography. 325419 100ul $708
1-(Tetrahydro-2H-pyran-4-yl)ethanone Asreported 290674 250mg $460
NDUFAB1 Purifiedbyimmunoaffinitychromatography. 325418 50ul $509
More product size

1-(Tetrahydro-2H-pyran-4-yl)ethanone Properties

Boiling point 90-94℃/15mm
Density 1.024
refractive index 1.4530
storage temp. -20°C
form Liquid
color Colorless to pale yellow
InChI InChI=1S/C7H12O2/c1-6(8)7-2-4-9-5-3-7/h7H,2-5H2,1H3
InChIKey VNMXIOWPBADSIC-UHFFFAOYSA-N
SMILES C(=O)(C1CCOCC1)C

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xn
Risk Statements  42-36
Safety Statements  22-45-26
HS Code  2933998090
NFPA 704
1
2 0

1-(Tetrahydro-2H-pyran-4-yl)ethanone price More Price(82)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 325419 NDUFAB1 Purifiedbyimmunoaffinitychromatography. 50ul $509 2026-06-03 Buy
Usbiological 290674 1-(Tetrahydro-2H-pyran-4-yl)ethanone Asreported 137052-08-5 100mg $333 2026-06-03 Buy
Usbiological 325419 NDUFAB1 Purifiedbyimmunoaffinitychromatography. 100ul $708 2026-06-03 Buy
Usbiological 290674 1-(Tetrahydro-2H-pyran-4-yl)ethanone Asreported 137052-08-5 250mg $460 2026-06-03 Buy
Usbiological 325418 NDUFAB1 Purifiedbyimmunoaffinitychromatography. 50ul $509 2026-06-03 Buy
Product number Packaging Price Buy
325419 50ul $509 Buy
290674 100mg $333 Buy
325419 100ul $708 Buy
290674 250mg $460 Buy
325418 50ul $509 Buy

1-(Tetrahydro-2H-pyran-4-yl)ethanone Chemical Properties,Uses,Production

Uses

1-(Tetrahydro-2H-pyran-4-yl)ethanone is mainly used as an intermediate in organic synthesis and medicinal chemistry, and can be used in the synthesis of cell biology detection reagents. In organic synthetic transformations, the keto carbonyl group in 1-(Tetrahydro-2H-pyran-4-yl)ethanone can be reacted with Wittig's reagent to prepare a variety of polysubstituted olefinic compounds, and in addition, the keto carbonyl group can be reduced to a hydroxyl group by the corresponding reducing agent.

Synthesis

Ethyl 4-acetyl tetrahydro-2H-pyran-4-carboxylate

345216-96-8

1-(Tetrahydro-2H-pyran-4-yl)ethanone

137052-08-5

Example 1 (Synthesis of 4-acetyltetrahydropyran) In a 10 mL glass flask equipped with a stirring device, a thermometer and a reflux condenser, 0.38 g (2.0 mmol) of methyl 4-acetyltetrahydro-2H-pyran-4-carboxylate (synthesized according to the method of Reference Example 1) of 99% purity and 1.08 mL (10 mmol) of 9 mol/L sulfuric acid were added. The reaction mixture was heated to 120°C under stirring and the reaction lasted for 1.5 hours. Upon completion of the reaction, the reaction mixture was analyzed by gas chromatography (internal standard method) and the formation of 0.25 g (yield: 96%) of 4-acetyltetrahydropyran was confirmed.

References

[1] Patent: EP1700852, 2006, A1. Location in patent: Page/Page column 7-8
[2] Patent: EP1700852, 2006, A1. Location in patent: Page/Page column 8
[3] Patent: WO2011/50016, 2011, A1. Location in patent: Page/Page column 35-36

156353-01-4
75-16-1
137052-08-5
Synthesis of 1-(Tetrahydro-2H-pyran-4-yl)ethanone from N-Methoxy-N-Methyltetrahydropyran-4-carboxaMide and Methylmagnesium Bromide
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View Lastest Price from 1-(Tetrahydro-2H-pyran-4-yl)ethanone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-(Tetrahydro-2H-pyran-4-yl)ethanone pictures 2026-08-01 1-(Tetrahydro-2H-pyran-4-yl)ethanone
137052-08-5
1KG 97%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
1-(Tetrahydro-2H-pyran-4-yl)ethanone pictures 2023-03-29 1-(Tetrahydro-2H-pyran-4-yl)ethanone
137052-08-5
1kg 98% 1000kg LY Global chemicals co.,ltd .
1-(Tetrahydro-2h-pyran-4-yl)ethanone pictures 2022-01-27 1-(Tetrahydro-2h-pyran-4-yl)ethanone
137052-08-5
1KG 99.5% 100 tons Honest Joy Holdings Limited

1-(Tetrahydro-2H-pyran-4-yl)ethanone Spectrum

4-ACETYLTETRAHYDRO-4H-PYRAN 1-ACETOXY-3-CARBAMOYL,2,2,5,5-TETRAMETHYLPYRROLIDINE Ethanone, 1-(tetrahydro-2H-pyran-4-yl)- (9CI) Ethanone, 1-(tetrahydro-2H-pyran-4-yl) 1-(tetrahydro-2H-pyran-4-yl)ethanone 1-Tetrahydropyran-4-yl-ethanone 1-(Tetrahydro-2H-pyran-4-yl)ethan-1-one, 4-Acetyloxane 4-Acetyltetrahydro-2H-pyran 1-(oxan-4-yl)ethan-1-one FASN2A MGC65095 NDUFAB1 EOS-61643 1-(oxan-4-yl)ethanone 4-Acetyltetrahydro-2H-pyran 97% 1-(TETRAHYDRO-2H-PYRAN-4-YL)ETHANE -1-ONE 1-(oxan-4-yL 4-Acetyltetrahydropyran,97% 137052-08-5 1-(tetrahydro-2H-pyran-4-yl)ethan-1-one 4-Acetyltetrahydropyran ACP 137052-08-5 137502-08-5 ACETYLGROUP API