SQUALESTATIN

SQUALESTATIN 구조식 이미지
카스 번호:
144541-82-2
상품명:
SQUALESTATIN
동의어(영문):
L-694,599;SQUALESTATIN;ZARAGOZIC ACID A SODIUM SALT;Zaragozic acid A trisodium salt
CBNumber:
CB7779233
분자식:
C35H47NaO14
포뮬러 무게:
714.74
MOL 파일:
Mol file

SQUALESTATIN 속성

저장 조건
-20°C
용해도
DMSO: 9.80-10.20mg/mL, clear, colorless to faintly yellow
물리적 상태
lyophilized powder
생물학적 소스
microbial

안전

WGK 독일 3
스토리지 클래스 11 - Combustible Solids

SQUALESTATIN C화학적 특성, 용도, 생산

용도

Zaragozic acid A trisodium salt is a potent inhibitor of squalene synthase.

Biochem/physiol Actions

Potent inhibitor, in vivo and in vitro, of mammalian, fungal and Saccharomyces cervisiae squalene synthase. Squalene synthase is the first committed enzyme in sterol synthesis, catalyzing the reductive condensation of farnesyl pyrophosphate to form squalene. As a squalene synthase inhibitor, zaragozic acid produces lower plasma cholesterol levels in primates. Treatment of rats with zaragozic acid A caused an increase in hepatic low density lipoprotein (LDL) receptor mRNA levels.

SQUALESTATIN 준비 용품 및 원자재

원자재

준비 용품


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