ANISOMYCIN manufacturers and suppliers

ANISOMYCIN suppliers

Properties

Melting point:: 140-141 C

alpha: D23 -30° (methanol)

Boiling point:: 408.52°C (rough estimate)

Density: 1.1356 (rough estimate)

refractive index: 1.5230 (estimate)

Flash point:: 87℃

storage temp.: Inert atmosphere,Store in freezer, under -20°C

solubility: methanol: 20 mg/mL, clear, colorless to faintly yellow

pka: 7.9(at 25℃)

form: solid

color: white

Water Solubility: Soluble in water at 2 mg/ml, in DMSO at 20mg/ml, and in methanol at 20mg/ml

λmax: 283nm(EtOH)(lit.)

Merck: 14,670

BRN: 20705

Stability:: Stable. Incompatible with strong oxidizing agents.

InChI: 1S/C14H19NO4/c1-9(16)19-14-12(15-8-13(14)17)7-10-3-5-11(18-2)6-4-10/h3-6,12-15,17H,7-8H2,1-2H3/t12-,13+,14+/m1/s1

InChIKey: YKJYKKNCCRKFSL-RDBSUJKOSA-N

SMILES: COc1ccc(C[C@H]2NC[C@H](O)[C@H]2OC(C)=O)cc1

Safety Information

Symbol(GHS): GHS06

Signal word: Danger

Hazard statements: H301

Precautionary statements: P264-P270-P301+P310-P405-P501

PPE: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Hazard Codes: T,Xn

Risk Statements: 25-36/37/38-20/21/22

Safety Statements: 45-36-26

RIDADR: UN 3462 6.1/PG 3

WGK Germany: 3

RTECS: BZ9800000

F: 3-10

HazardClass: 6.1(b)

PackingGroup: III

HS Code: 29419090

Storage Class: 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects

Hazard Classifications: Acute Tox. 3 Oral

Toxicity: LD50 orl-rat: 72 mg/kg ANTCAO 5,490,55

Use

Anisomycin is a phenylmethylenepyrrolidine first isolated from Streptomyces griseolus in 1954 as an antiprotozoan with antifungal activity. Anisomycin is an inhibitor of protein synthesis by binding to the 60S ribosomal subunit. Interestingly, anisomycin has found use for the induction of amnesia in animal models. More recently, anisomycin has been demonstrated to induce apoptosis, to be a selective signalling agonist, to activate mitogen-activated protein (MAP) kinases and to be immunomodulatory via its action on T cells.

You can find ANISOMYCIN suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.