FLECAINIDE ACETATE manufacturers and suppliers

FLECAINIDE ACETATE suppliers

Properties

Melting point:: 145-147℃

storage temp.: 2-8°C

solubility: Soluble in water and in anhydrous ethanol. It is freely soluble in dilute acetic acid and practically insoluble in dilute hydrochloric acid.

form: Solid

color: White

Water Solubility: Soluble in dilute acetic acid, dimethyl sulfoxide, ethanol, methanol and water.

Stability:: Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month.

Major Application: pharmaceutical (small molecule)

InChIKey: RKXNZRPQSOPPRN-UHFFFAOYSA-N

SMILES: C1(C=C(C=CC=1OCC(F)(F)F)OCC(F)(F)F)C(=O)NCC1NCCCC1.C(=O)(O)C

Safety Information

Symbol(GHS): GHS07,GHS08

Signal word: Danger

Hazard statements: H302-H315-H319-H335-H360FD

Precautionary statements: P201-P202-P301+P312-P302+P352-P305+P351+P338-P308+P313

target organs: Respiratory system

Hazard Codes: Xn

Risk Statements: 22-36/37/38-63

Safety Statements: 22-26-36/37/39-45-46

RIDADR: 3249

WGK Germany: -

RTECS: CV5792550

HazardClass: 6.1(b)

PackingGroup: III

HS Code: 2933399090

Storage Class: 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects

Hazard Classifications: Acute Tox. 4 Oral
Eye Irrit. 2
Repr. 1B
Skin Irrit. 2
STOT SE 3

Use

Flecainide acetate, N-(2-piperidinylmethyl)-2,5-bis (2,2,2-trifluoroethoxy)benzamide monoacetate(Tambocor), is a class IC antiarrhythmic drug withlocal anesthetic activity; it is a chemical derivative of benzamide.The drug undergoes biotransformation, forming ameta-O-dealkylated compound, whose antiarrhythmic propertiesare half as potent as those of the parent drug, and ameta-O-dealkylated lactam of flecainide with little pharmacologicalactivity. Flecainide acetate is given orally to suppresschronic ventricular ectopy and ventricular tachycardia.It has some limitations because of CNS side effects.

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