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ChemicalBook >> CAS DataBase List >> NVP-TAE684

NVP-TAE684

$30 - $4070
Product name: NVP-TAE684
CAS: 761439-42-3
MF: C30H40ClN7O3S
MW: 614.2
EINECS:-0
MDL Number:MFCD11977634
Synonyms:NVP-TAE684 - TAE 684;5-Chloro-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-2,4-pyrimidinediamine;NVP-TAE 684;5-Chloro-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-2,4-pyrimidinediamine TAE684 (NVP-TAE684);NVP-TAE684 5-Chloro-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-2,4-pyrimidinediamine;2,4-Pyrimidinediamine, 5-chloro-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-;TAE684 (NVP-TAE684);NV--TAE684

Price68 Properties Safety Information Description

68 prices

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Brand

aablocks
ACHEMBLOCK
Adipogen Life Sciences
AK Scientific
Ambeed
American Custom Chemicals Corporation
ApexBio Technology
Arctom
Axon Medchem
Biorbyt Ltd
Biosynth
Cayman Chemical
Chemenu
ChemScene
Crysdot
DC Chemicals
Labseeker
Matrix Scientific
Medical Isotopes, Inc.
TRC

Package

1mg
2MG
5mg
10mg
10mM*1mLinDMSO
25mg
50mg
100.00mg
100mg
250mg
1.00g
1000mg
1G
EvaluationSample
10mM(in1mLDMSO)

Manufactureraablocks
Product numberAA00G3MN
Product description5-Chloro-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-2,4-pyrimidinediamine 98%
Packaging25mg
Price$134
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00G3MN
Product description5-Chloro-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-2,4-pyrimidinediamine 98%
Packaging50mg
Price$211
Updated2026-05-28
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Manufactureraablocks
Product numberAA00G3MN
Product description5-Chloro-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-2,4-pyrimidinediamine 98%
Packaging100mg
Price$314
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00G3MN
Product description5-Chloro-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-2,4-pyrimidinediamine 98%
Packaging250mg
Price$599
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00G3MN
Product description5-Chloro-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-2,4-pyrimidinediamine 98%
Packaging10mg
Price$79
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00G3MN
Product description5-Chloro-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-2,4-pyrimidinediamine ≥98%
Packaging5mg
Price$56
Updated2026-05-28
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Manufactureraablocks
Product numberAA00G3MN
Product description5-Chloro-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-2,4-pyrimidinediamine ≥95%
Packaging1mg
Price$41
Updated2026-05-28
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ManufacturerACHEMBLOCK
Product number10391
Product descriptionTAE684 98%
Packaging5MG
Price$41
Updated2026-05-27
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ManufacturerACHEMBLOCK
Product number10391
Product descriptionTAE684 98%
Packaging1G
Price$1125
Updated2026-05-27
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ManufacturerACHEMBLOCK
Product number10391
Product descriptionTAE684 98%
Packaging100MG
Price$315
Updated2026-05-27
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ManufacturerACHEMBLOCK
Product number10391
Product descriptionTAE684 98%
Packaging25MG
Price$122
Updated2026-05-27
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ManufacturerAdipogen Life Sciences
Product numberSYN-1159-M005
Product descriptionTAE684 ≥95%
Packaging5mg
Price$173
Updated2026-05-06
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ManufacturerAdipogen Life Sciences
Product numberSYN-1159-M001
Product descriptionTAE684 ≥95%
Packaging1mg
Price$97
Updated2026-05-06
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ManufacturerAdipogen Life Sciences
Product numberSYN-1159-M010
Product descriptionTAE684 ≥95%
Packaging10mg
Price$270
Updated2026-05-06
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ManufacturerAdipogen Life Sciences
Product numberSYN-1159-M050
Product descriptionTAE684 ≥95%
Packaging50mg
Price$799
Updated2026-05-06
Buy

ManufacturerAK Scientific
Product numberSYN1159
Product descriptionTAE684
Packaging5mg
Price$180
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA00G3MN	5-Chloro-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-2,4-pyrimidinediamine 98%	25mg	$134	2026-05-28	Buy
aablocks	AA00G3MN	5-Chloro-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-2,4-pyrimidinediamine 98%	50mg	$211	2026-05-28	Buy
aablocks	AA00G3MN	5-Chloro-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-2,4-pyrimidinediamine 98%	100mg	$314	2026-05-28	Buy
aablocks	AA00G3MN	5-Chloro-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-2,4-pyrimidinediamine 98%	250mg	$599	2026-05-28	Buy
aablocks	AA00G3MN	5-Chloro-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-2,4-pyrimidinediamine 98%	10mg	$79	2026-05-28	Buy
aablocks	AA00G3MN	5-Chloro-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-2,4-pyrimidinediamine ≥98%	5mg	$56	2026-05-28	Buy
aablocks	AA00G3MN	5-Chloro-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-2,4-pyrimidinediamine ≥95%	1mg	$41	2026-05-28	Buy
ACHEMBLOCK	10391	TAE684 98%	5MG	$41	2026-05-27	Buy
ACHEMBLOCK	10391	TAE684 98%	1G	$1125	2026-05-27	Buy
ACHEMBLOCK	10391	TAE684 98%	100MG	$315	2026-05-27	Buy
ACHEMBLOCK	10391	TAE684 98%	25MG	$122	2026-05-27	Buy
Adipogen Life Sciences	SYN-1159-M005	TAE684 ≥95%	5mg	$173	2026-05-06	Buy
Adipogen Life Sciences	SYN-1159-M001	TAE684 ≥95%	1mg	$97	2026-05-06	Buy
Adipogen Life Sciences	SYN-1159-M010	TAE684 ≥95%	10mg	$270	2026-05-06	Buy
Adipogen Life Sciences	SYN-1159-M050	TAE684 ≥95%	50mg	$799	2026-05-06	Buy
AK Scientific	SYN1159	TAE684	5mg	$180	2021-12-16	Buy

Next Last

Properties

Melting point :166-169°C
Boiling point :791.0±70.0 °C(Predicted)
Density :1.296
storage temp. :Refrigerator, under inert atmosphere
solubility :Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
form :Solid
pka :8.14±0.42(Predicted)
color :White to Pale Yellow
InChIKey :QQWUGDVOUVUTOY-UHFFFAOYSA-N
SMILES :C1(NC2=CC=C(N3CCC(N4CCN(C)CC4)CC3)C=C2OC)=NC=C(Cl)C(NC2=CC=CC=C2S(C(C)C)(=O)=O)=N1
CAS DataBase Reference :761439-42-3

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

TAE684 (NVP-TAE684) is a potent and selective ALK inhibitor with IC50 of 3 nM in a cell-free assay, 100-fold more sensitive for ALK than InsR.

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Suppliers and manufacturers

ShangHai Biochempartner Co.,Ltd Shanghai Boyle Chemical Co., Ltd. J & K SCIENTIFIC LTD. Chembest Research Laboratories Limited Capot Chemical Co., Ltd JinYan Chemicals(ShangHai) Co.,Ltd. Chemsky（shanghai）International Co.,Ltd. Jinan Trio PharmaTech Co., Ltd. Dalian Meilun Biotech Co., Ltd. Shanghai civi chemical technology co.,Ltd

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NVP-TAE684

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Description

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