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| | Olivomycin Basic information |
| Product Name: | Olivomycin | | Synonyms: | Olivomycin;olivomycin A;3'''-O-[3-C-Methyl-4-O-(2-methyl-1-oxopropyl)-2,6-dideoxy-α-L-arabino-hexopyranosyl]olivomycin D;D-threo-2-Pentulose, 1-C-[(2S,3S)-7-[[4-O-acetyl-2,6-dideoxy-3-O-(2,6-dideoxy-4-O-methyl-α-D-lyxo-hexopyranosyl)-β-D-lyxo-hexopyranosyl]oxy]-3-[[O-2,6-dideoxy-3-C-methyl-4-O-(2-methyl-1-oxopropyl)-α-L-arabino-hexopyranosyl-(1→3)-O-2,6-dideoxy-β-D-arabino-hexopyranosyl-(1→3)-2,6-dideoxy-β-D-arabino-h... | | CAS: | 6988-58-5 | | MF: | C58H84O26 | | MW: | 1197.27 | | EINECS: | | | Product Categories: | | | Mol File: | 6988-58-5.mol |  |
| | Olivomycin Chemical Properties |
| Melting point | 160-165° | | alpha | D20 -36° (c = 0.5 in ethanol) | | Boiling point | 782.67°C (rough estimate) | | density | 1.1373 (rough estimate) | | refractive index | 1.6500 (estimate) | | pka | 4.36±0.60(Predicted) | | color | Yellow crystals |
| Toxicity | LD50 i.v. in mice: 13.75 mg/kg (Slavik, Carter) |
| | Olivomycin Usage And Synthesis |
| Definition | ChEBI: Olivomycin A is an olivomycin and a secondary alpha-hydroxy ketone. It has a role as an antimicrobial agent. | | Safety Profile | Poison by intraperitoneal andintravenous routes. | | Enzyme inhibitor | These chromomycin-like antibiotics (FWOlivomycin-A = 1197.3 g/mol; CAS 6988-58-5) produced by Streptomyces olivoreticuli anthat bind to DNA in a base pair-specific manner, preferring Guanine:Cytosine pairs. The major component, olivimycin A, is a yellow solid that is insoluble in water and soluble in ethanol and chloroform. Target(s): DNA-directed DNA polymerase; DNA-directed RNA polymerase; EcoRI restriction endonuclease, or Type II site-specific deoxyribonuclease. |
| | Olivomycin Preparation Products And Raw materials |
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