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DIPHENYL PHOSPHITE

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DIPHENYL PHOSPHITE Basic information
Product Name:DIPHENYL PHOSPHITE
Synonyms:Diphenyl phosphite, contains varying amounts of phenol and (C6H5O)3P;Phosphonic acid diphenyl;Phosphorous acid diphenyl;Diphenyl Phosphite (contains 5% Phenol at maximum);Diphenyl Phosphonate Phosphonic Acid Diphenyl Ester Phosphorous Acid Diphenyl Ester;(contains 5% Phenol at MaxiMuM);Diphenyl Phosphite ;Diphenyl phosphite, contains varying aMounts of phenol and (C6H5O)3P 5GR
CAS:4712-55-4
MF:C12H11O3P
MW:234.19
EINECS:225-202-8
Product Categories:Organic Building Blocks;Organic Phosphates/Phosphites;Phosphorus Compounds
Mol File:4712-55-4.mol
DIPHENYL PHOSPHITE Structure
DIPHENYL PHOSPHITE Chemical Properties
Melting point 12 °C (lit.)
Boiling point 218-219 °C/26 mmHg (lit.)
density 1.223 g/mL at 25 °C (lit.)
vapor density 8.1 (vs air)
vapor pressure 5 mm Hg ( 140 °C)
refractive index n20/D 1.558(lit.)
Fp 350 °F
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form Liquid
Specific Gravity1.223
color Clear
BRN 2051909
InChIKeyOGBPILLJZSJJRC-UHFFFAOYSA-N
LogP2.4 at 25℃ and pH7
CAS DataBase Reference4712-55-4(CAS DataBase Reference)
EPA Substance Registry SystemDiphenyl phosphite (4712-55-4)
Safety Information
Hazard Codes Xn
Risk Statements 22-37/38-41
Safety Statements 26-39
RIDADR 1760
WGK Germany 3
21
HazardClass 8
PackingGroup III
HS Code 29209090
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
DIPHENYL PHOSPHITE Usage And Synthesis
Chemical Propertiesclear liquid
UsesDiphenyl Phosphite is a reactant used in the synthesis of α-hydroxyphosphonates and α-hydroxyphosphinates for their antioxidant and antimicrobial activity.
Synthesis
phenyl hydrogen phosphonate

2310-89-6

Phenol

108-95-2

DIPHENYL PHOSPHITE

4712-55-4

In a three-necked round-bottomed flask equipped with a mechanical stirrer, a reflux condenser and a dropping funnel, the first P-O component (PIII-OH) is added under nitrogen protection. This P-O component (see column 5 of Table 1) may be selected from H3PO3, monoalkyl phosphite or mixtures thereof and may additionally comprise dialkyl phosphite. Subsequently, the first P-O component is heated to the temperature specified in column 11 of Table 1 (T° step a) for step a). Next, the second P-O component (see column 6 of Table 1) is added while maintaining the appropriate temperature. The mixture was allowed to react for the time indicated in column 13 of Table 1 (reaction time step a), followed by step b). The alcohol R1-OH (see column 3 of Table 1) is then added dropwise while maintaining the temperature specified in column 12 of Table 1 (T° step b). After the mixture was reacted for the time indicated in column 14 of Table 1 (reaction time b), it was cooled to room temperature and analyzed by 31P NMR.

Purification MethodsDiphenyl Phosphite can be purified by distillation. Best done in small batches since decomposition frequently occurs. Phenol can be substantially removed by heating at 150 °C at water pump vacuum.
References[1] Patent: EP2581378, 2013, A1. Location in patent: Paragraph 0038; 0039; 0043
Tag:DIPHENYL PHOSPHITE(4712-55-4) Related Product Information
Triphenyl phosphate Glycol sulfite Dimethyl phosphite Triethyl phosphite DI-N-PROPYL SULFITE DIAMYL SULFITE TETRAETHYL ETHYLENEDIPHOSPHONATE DIETHYL ETHYLIDENEMALONATE GLYOXAL SODIUM BISULFITE SODIUM PHOSPHITE-5-HYDRATE Monopotassium phosphite LINOLENIC ACID ETHYL ESTER PHOSPHOROUS ACID TRI-O-CRESYL ESTER Dibenzyl phosphite METHYL LINOLENATE Diisopropyl phosphite Phosphorous acid, bis(1-methylethyl) ester Dimethyl sulfite

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