- Nodakenin
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- $45.00
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2026-07-27
- CAS:495-31-8
- Purity: 98.31%
- Supply Ability: 10g
- Nodakenin
-
- $10.00
-
2026-03-20
- CAS:495-31-8
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 5tons
- Nodakenin
-
- $8.00
-
2025-05-26
- CAS:495-31-8
- Min. Order: 1kg
- Purity: 0.99
- Supply Ability: 10000
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| | Nodakenin Basic information |
| Product Name: | Nodakenin | | Synonyms: | (R)-2-[1-(β-D-Glucopyranosyloxy)-1-methylethyl]-2,3-dihydro-7H-furo[3,2-g][1]benzopyran-7-one;NODAKENIN;(2R)-2-[2-[(2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxypropan-2-yl]-2,3-dihydrofuro[3,2-g]chromen-7-one;2-(7-Oxo-2,3-dihydro-7H-furo[3,2-g]chromen-3-yl)-2-propanyl β-D-glucopyranoside;Nodakenin, 98%, from Angelica decursiva (Miq.) Franch. & Sav.;AliNodakenin;7H-Furo[3,2-g][1]benzopyran-7-one, 2-[1-(β-D-glucopyranosyloxy)-1-methylethyl]-2,3-dihydro-, (2R)-;Nodakenin USP/EP/BP | | CAS: | 495-31-8 | | MF: | C20H24O9 | | MW: | 408.4 | | EINECS: | | | Product Categories: | chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract | | Mol File: | 495-31-8.mol |  |
| | Nodakenin Chemical Properties |
| Melting point | melting at 216° | | alpha | D30 +56.6° | | Boiling point | 657.1±55.0 °C(Predicted) | | density | 1.51±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C(protect from light) | | solubility | Chloroform (Slightly, Sonicated), DMSO (Slightly) | | form | Solid | | pka | 12.90±0.70(Predicted) | | color | Off-White to Pale Beige | | Major Application | food and beverages | | InChIKey | HXCGUCZXPFBNRD-VPVUCYOBNA-N | | SMILES | C([C@@H]1OC2=CC3OC(=O)C=CC=3C=C2C1)(C)(C)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O |&1:1,18,19,20,22,24,r| |
| Safety Statements | 24/25 | | WGK Germany | WGK 3 | | HS Code | 29389090 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Oral |
| | Nodakenin Usage And Synthesis |
| Chemical Properties | White crystalline powder, soluble in methanol, derived from the plant Peucedanum purpurogenum and Angelica radix. | | Uses | Nodakenin is a compound used for inhibiting influenza virus including Nodakenin and/or Nodakenetin. | | Definition | ChEBI: Nodakenin is a furanocoumarin. | | Synthesis | 1. Rhizome of Qianghuo is extracted with ethanol, concentrated, and acid-hydrolyzed. The hydrolysate is passed through macroporous resin. Elution with ethanol of varying concentrations yields an extract rich in the target.
2. The extract is mixed with silica gel and subjected to silica column chromatography with a petroleum ether-ethyl acetate gradient. The 10:1 fraction is collected and purified by preparative HPLC to obtain nodakenin. | | in vivo | Nodakenin (10 mg/kg, p.o.) reverses scopolamine-induced cognitive impairments in the passive avoidance test and the Y-maze test[1].
Nodakenin (10 mg/kg, p.o.) reduces escape latency during training in the Morris water maze test[1].
| Animal Model: | Male ICR mice
| | Dosage: | 2.5, 5, 10 and 20 mg/kg
| | Administration: | p.o, single dose
| | Result: | Reversed in step-through latency induced by scopolamine. |
| | IC 50 | AChE |
| | Nodakenin Preparation Products And Raw materials |
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