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| | 2-Amino-5-bromonicotinic acid Basic information | | Uses |
| | 2-Amino-5-bromonicotinic acid Chemical Properties |
| Melting point | 253-255°C | | Boiling point | 350.4±42.0 °C(Predicted) | | density | 1.909 | | refractive index | 1.5150 (estimate) | | storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C | | pka | 2.55±0.10(Predicted) | | form | powder | | color | Pale yellow | | CAS DataBase Reference | 52833-94-0(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 37/39-26 | | RIDADR | UN2811 | | HazardClass | IRRITANT | | HS Code | 29333990 |
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ACROS
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| | 2-Amino-5-bromonicotinic acid Usage And Synthesis |
| Uses | 2-Amino-5-bromonicotinic acid is an organic intermediate that can be prepared by brominating 2-aminonicotinic acid. Literature reports that 2-amino-5-bromonicotinic acid can be used to prepare 6-pyrazole-substituted quinazoline compounds and their derivatives. These compounds exhibit high tyrosine kinase inhibitory activity and strong inhibitory activity against human breast cancer cells and lung adenocarcinoma cells. | | Chemical Properties | Light yellow powder | | References | [1] Patent: US6369056, 2002, B1 [2] Patent: US6399593, 2002, B1 [3] Patent: US2006/30583, 2006, A1. Location in patent: Page/Page column 113 [4] Patent: CN106565684, 2017, A. Location in patent: Paragraph 0177; 0178; 0179; 0180 [5] Patent: WO2014/209727, 2014, A1. Location in patent: Page/Page column 60-61 |
| | 2-Amino-5-bromonicotinic acid Preparation Products And Raw materials |
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