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2-Amino-5-bromonicotinic acid

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Company Name: Hebei Chuanghai Biotechnology Co., Ltd
Tel: +86-15350571055
Email: Sibel@chuanghaibio.com
Products Intro: Product Name:2-Amino-5-bromonicotinic acid
CAS:52833-94-0
Purity:99%
Company Name: Shaanxi Haibo Biotechnology Co., Ltd
Tel: +86-18629295024
Email: qinhe02@xaltbio.com
Products Intro: Product Name:2-Amino-5-bromonicotinic acid
CAS:52833-94-0
Purity:99% Package:25kg Remarks:Pale yellow powder
Company Name: Hebei Zhuanglai Chemical Trading Co Ltd
Tel: +86-16264648883
Email: niki@zlchemi.com
Products Intro: Product Name:2-Amino-5-bromonicotinic acid
CAS:52833-94-0
Purity:99% Package:1kg;10USD
Company Name: career henan chemical co
Tel: +86-0371-86658258
Email: sales@coreychem.com
Products Intro: Product Name:2-Amino-5-bromonicotinic acid
CAS:52833-94-0
Purity:99% Package:1kg;2USD
Company Name: Changzhou Ansciep Chemical Co., Ltd.
Tel: +86 519 86305871
Email: sales@ansciepchem.com
Products Intro: Product Name:2-Amino-5-bromonicotinic acid
CAS:52833-94-0
Purity:98% Package:100g, 500g, 1kg, 25kg, 50kg, 200kg Remarks:Good quality; Large stock; Hot sale

2-Amino-5-bromonicotinic acid manufacturers
2-Amino-5-bromonicotinic acid Basic information
Uses
Product Name:2-Amino-5-bromonicotinic acid
Synonyms:2-Amino-5-bromonicotinic acid ,97%;2-Amino-5-bromonicotinic acid,95%;2-Amino-5-bromonicotinic ...;2-Amino-5-bromonicotonic acid;1-AMino-5-broMonicotinic acid;2-AMINO-5-BROMONICOTINIC ACID;5-Bromo-2-Amino Nicotinic Acid;2-Amino-5-bromonicotinic acid 95%
CAS:52833-94-0
MF:C6H5BrN2O2
MW:217.02
EINECS:
Product Categories:Amines;blocks;Bromides;Carboxes;Pyridines;Amino Acids and Derivatives;Heterocycle-Pyridine series;pharmacetical;Carboxylic Acids;Pyridine;Carboxylic Acids
Mol File:52833-94-0.mol
2-Amino-5-bromonicotinic acid Structure
2-Amino-5-bromonicotinic acid Chemical Properties
Melting point 253-255°C
Boiling point 350.4±42.0 °C(Predicted)
density 1.909
refractive index 1.5150 (estimate)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka2.55±0.10(Predicted)
form powder
color Pale yellow
CAS DataBase Reference52833-94-0(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 37/39-26
RIDADR UN2811
HazardClass IRRITANT
HS Code 29333990
MSDS Information
ProviderLanguage
ACROS English
2-Amino-5-bromonicotinic acid Usage And Synthesis
Uses2-Amino-5-bromonicotinic acid is an organic intermediate that can be prepared by brominating 2-aminonicotinic acid. Literature reports that 2-amino-5-bromonicotinic acid can be used to prepare 6-pyrazole-substituted quinazoline compounds and their derivatives. These compounds exhibit high tyrosine kinase inhibitory activity and strong inhibitory activity against human breast cancer cells and lung adenocarcinoma cells.
Chemical PropertiesLight yellow powder
References[1] Patent: US6369056, 2002, B1
[2] Patent: US6399593, 2002, B1
[3] Patent: US2006/30583, 2006, A1. Location in patent: Page/Page column 113
[4] Patent: CN106565684, 2017, A. Location in patent: Paragraph 0177; 0178; 0179; 0180
[5] Patent: WO2014/209727, 2014, A1. Location in patent: Page/Page column 60-61
2-Amino-5-bromonicotinic acid Preparation Products And Raw materials
Raw materialsMethanol-->Acetic acid-->Petroleum ether-->Chloroform-->Bromine-->Acetic anhydride-->Ammonium hydroxide-->Chlorine-->Zinc chloride-->Malononitrile-->1,1,3,3-Tetramethoxypropane
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