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DL-GLUTAMIC-2,4,4-D3 ACID

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DL-GLUTAMIC-2,4,4-D3 ACID manufacturers

DL-GLUTAMIC-2,4,4-D3 ACID Basic information
Product Name:DL-GLUTAMIC-2,4,4-D3 ACID
Synonyms:DL-GLUTAMIC-2,4,4-D3 ACID;DL-GLUTAMIC ACID (2,4,4-D3);DL-Glutamic Acid-2,2,4-D3;DL-GlutaMic-d3 Acid;2-Aminopentanedioic acid-2,4,4-d3;(2R,S)-<2,4,4-(2)H3>-glutamic acid;DL-GLUTAMIC-2,4,4-D3 ACID USP/EP/BP;DL-Glutamic acid-d3
CAS:96927-56-9
MF:C5H9NO4
MW:147.13
EINECS:
Product Categories:Amino Acids 13C, 2H, 15N
Mol File:96927-56-9.mol
DL-GLUTAMIC-2,4,4-D3 ACID Structure
DL-GLUTAMIC-2,4,4-D3 ACID Chemical Properties
Melting point 185 °C (dec)(lit.)
storage temp. -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly, Heated), Water (Slightly)
form Solid
color White to Off-White
Appearancewhite solid
CAS Number Unlabeled617-65-2
Safety Information
MSDS Information
DL-GLUTAMIC-2,4,4-D3 ACID Usage And Synthesis
Description

Glutamic acid together with its γ-monoamide – glutamine – makes up about a third of all free amino acids in blood plasma, its content in body proteins is 20-25 %. In the blood, glutamic acid maintains pH balance, binds excess ammonia, turning into glutamine, transports it to the site of detoxification, and serves as a reserve of amino groups. Glutamic acid acts as an excitatory neurotransmitter and agonist of all subtypes of glutamate receptors (metabotropic, kainate, NMDA and AMPA), and is also a precursor of gamma-aminobutyric acid (GABA). Glutamic acid has an immunomodulatory effect and affects many metabolic processes.

UsesDL-Glutamic acid-d3 is the deuterium labeled DL-Glutamic acid. DL-Glutamic acid is the conjugate acid of Glutamic acid, which acts as a fundamental metabolite. Comparing with the second phase of polymorphs α and β L-Glutamic acid, DL-Glutamic acid presents better stability[1].
References[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110
DL-GLUTAMIC-2,4,4-D3 ACID Preparation Products And Raw materials
Tag:DL-GLUTAMIC-2,4,4-D3 ACID(96927-56-9) Related Product Information
L-Glutamic acid GLDH Polyglutamic acid D-Glutamic acid-d5 DL-Glutamic acid L-GLUTAMIC-2,3,3,4,4-D5 ACID N-ACETYL-L-GLUTAMIC-2,3,3,4,4-D5 ACID PEMETREXED-D5 L-GLUTAMIC ACID (2,4,4-D3) L-Glutamic acid-15N,d9 L-Glutamic acid-13C5,15N,d9 DL-GLUTAMIC-2,3,3,4,4-D5 ACID DL-GLUTAMIC-2,4,4-D3 ACID N-ACETYL-D-GLUTAMIC-2,3,3,4,4-D5 ACID