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L-Glutamic-2,3,3,4,4-d5 acid

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L-Glutamic-2,3,3,4,4-d5 acid Basic information
Product Name:L-Glutamic-2,3,3,4,4-d5 acid
Synonyms:L-GLUTAMIC ACID (2,3,3,4,4-D5);L-GLUTAMIC ACID (2,3,3,4,4-D5, 97-98%);(2S)-2-AMinopentanedioic Acid-d5;(S)-(+)-GlutaMic Acid-d5;(S)-2-AMino-1,5-pentanedioic Acid-d5;(S)-2-AMinopentanedioic Acid-d5;1-AMinopropane-1,3-dicarboxylic Acid-d5;Glusate-d5
CAS:2784-50-1
MF:C5H4D5NO4
MW:152.16
EINECS:
Product Categories:Amino Acids & Derivatives, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals;Amino Acids;Amino AcidsStable Isotopes;G-H;Stable Isotopes;Alphabetical Listings;Amino Acids 13C, 2H, 15N
Mol File:2784-50-1.mol
L-Glutamic-2,3,3,4,4-d5 acid Structure
L-Glutamic-2,3,3,4,4-d5 acid Chemical Properties
Melting point 205 °C (dec.)(lit.)
Boiling point 333.783±32.00 °C(Press: 760.00 Torr)(predicted)
density 1.410±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
storage temp. Refrigerator
solubility Aqueous Acid (Slightly, Sonicated), Water (Slightly, Heated)
form Solid
pka2.174±0.10(predicted)
color White to Off-White
Optical Rotation[α]25/D +31°, c = 2 in 5 M HCl
Water Solubility Water : 14.29 mg/mL (93.91 mM; ultrasonic and warming and heat to 60°C)
CAS Number Unlabeled56-86-0
Safety Information
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
L-Glutamic-2,3,3,4,4-d5 acid Usage And Synthesis
Chemical PropertiesWhite Solid
UsesL-Glutamic Acid-d5 is an non-essential amino acid. Its salt form (glutamate) is an important neurotransmitter that plays a key role in long-term potentiation and is important for learning and memory. It is also a key molecule in cellular metabolism.
UsesA non-essential amino acid. Its salt form (glutamate) is an important neurotransmitter that plays a key role in long-term potentiation and is important for learning and memory. It is also a key molecule in cellular metabolism.
DefinitionChEBI: L-glutamic acid-d5 is a L-glutamic acid and a deuterated compound.
Biochem/physiol ActionsGlutamic acid (or glutamate) functions as a neurotransmitter and also serves as a precursor to other neurotransmitters such as gamma-aminobutyric acid. Glutamic acid also plays a key role in many metabolic pathways that controls growth, reproduction, maintenance and immunity. It is converted to α-ketoglutarate, a key component of the TCA (tricarboxylic acid) cycle and a precursor for the biosynthesis of nucleic acids and certain amino acids. In cells, glutamine is converted to glutamate by the enzyme glutaminase. Appl- L-Glutamic acid-2,3,3,4,4-d5 has been used as an internal standard in metabolomics and lipidomics profiling.
L-Glutamic-2,3,3,4,4-d5 acid Preparation Products And Raw materials
Raw materials2-Ketoglutaric acid
Tag:L-Glutamic-2,3,3,4,4-d5 acid(2784-50-1) Related Product Information
L-Cysteine L-Tryptophan L-Lysine 4-Aminobutyric acid DL-Glutamic-2,4,4-d3 Acid L-Glutamic acid Sodium nitrite D-Glutamic acid-d5 N-Acetyl-L-glutamic-2,3,3,4,4-d5 acid L-Glutamic-2,3,3,4,4-d5 acid N-Cbz-D-glutamic acid alpha-benzyl ester Boc-L-glutamic acid γ-cyclohexyl ester, Boc-L-glutamic acid 5-cyclohexyl ester DL-GLUTAMIC-2,3,3,4,4-D5 ACID N-ACETYL-D-GLUTAMIC-2,3,3,4,4-D5 ACID L-Glutamic acid-13C5,15N,d9 L-Glutamic acid-15N,d9 PEMETREXED-D5