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| | Bz-FVR-AMC (trifluoroacetate salt) Basic information |
| | Bz-FVR-AMC (trifluoroacetate salt) Chemical Properties |
| solubility | Water: 1 mg/ml |
| | Bz-FVR-AMC (trifluoroacetate salt) Usage And Synthesis |
| Description | Bz-FVR-AMC is a fluorogenic peptide substrate for bovine cathepsins S and H, Xenopus endopeptidase XSCEP1, and esterase E-II from B. gabonica venom, among others.1,2,3 Upon enzymatic cleavage, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify enzyme activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.WARNING This product is not for human or veterinary use. | | References | [1] XUE-QIN XIN Robert W M Bhadra Gunesekera. The specificity and elastinolytic activities of bovine cathepsins S and H[J]. Archives of biochemistry and biophysics, 1992, 299 2: Pages 334-339. DOI: 10.1016/0003-9861(92)90283-3
[2] NIGEL J. DARBY Derek G S David B LACKEY. Purification of a cysteine endopeptidase which is secreted with bioactive peptides from the epidermal glands of Xenopus laevis[J]. The FEBS journal, 1991, 195 1: 65-70. DOI: 10.1111/j.1432-1033.1991.tb15676.x
[3] FRANCOIS CLOETE Johannes C S Cornelis C Viljoen. Deviation from Michaelis - Menten kinetics for esterase E-II from the venom of Bitis gabonica, using synthetic arginine amides as substrates[J]. Toxicon, 1983, 21 6: Pages 857-869. DOI: 10.1016/0041-0101(83)90075-2 |
| | Bz-FVR-AMC (trifluoroacetate salt) Preparation Products And Raw materials |
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