N-(Amino-PEG3)-N-bis(PEG3-acid) HCl salt manufacturers
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| | N-(Amino-PEG3)-N-bis(PEG3-acid) HCl salt Basic information |
| Product Name: | N-(Amino-PEG3)-N-bis(PEG3-acid) HCl salt | | Synonyms: | N-(Amino-PEG3)-N-bis(PEG3-acid) HCl salt;UUN 42594;4,7,10,16,19,22-Hexaoxa-13-azapentacosanedioic acid, 13-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]-;N-(Amino-PEG3)-N-bis(PEG3-acid) HCl saltN- | | CAS: | 2055042-59-4 | | MF: | C26H52N2O13 | | MW: | 600.7 | | EINECS: | | | Product Categories: | | | Mol File: | 2055042-59-4.mol |  |
| | N-(Amino-PEG3)-N-bis(PEG3-acid) HCl salt Chemical Properties |
| Boiling point | 702.3±60.0 °C(Predicted) | | density | 1.166±0.06 g/cm3(Predicted) | | solubility | Soluble in Water, DMSO, DMF | | pka | 3.97±0.10(Predicted) |
| | N-(Amino-PEG3)-N-bis(PEG3-acid) HCl salt Usage And Synthesis |
| Description | N-(Amino-PEG3)-N-bis(PEG3-acid) is an aqueous soluble PEG reagent, . The amino group is reactive with activated NHS esters to form a amide bond.. The carboxylic acid groups (CO2H)can react with primary amine compound n the presence of activators. | | Uses | N-(Amino-PEG3)-N-bis(PEG3-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | N-(Amino-PEG3)-N-bis(PEG3-acid) HCl salt Preparation Products And Raw materials |
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