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| | L-ASCORBIC ACID 2-MONOPHOSPHATE TRI-CYCLOHEXYLAMMONIUM SALT Basic information |
| Product Name: | L-ASCORBIC ACID 2-MONOPHOSPHATE TRI-CYCLOHEXYLAMMONIUM SALT | | Synonyms: | Vitamin C phosphate;l-ascorbic acid 2-monophosphate tris-cyclohexylammonium salt;[2-(1,2-dihydroxyethyl)-3-hydroxy-5-oxo-2H-furan-4-yl] dihydrogen phosphate;Ascorbic Acid Impurity 6;ascorbate-2-phosphate;Ascorbyl monophosphate;Ascorbyl-2-monophosphate;Ascorbyl-2-phosphate | | CAS: | 23313-12-4 | | MF: | C6H9O9P | | MW: | 256.1 | | EINECS: | 601-297-5 | | Product Categories: | | | Mol File: | 23313-12-4.mol |  |
| | L-ASCORBIC ACID 2-MONOPHOSPHATE TRI-CYCLOHEXYLAMMONIUM SALT Chemical Properties |
| Boiling point | 682.7±65.0 °C(Predicted) | | density | 2.01±0.1 g/cm3(Predicted) | | form | Solid | | pka | 1.38±0.10(Predicted) | | color | Off-white to light yellow | | InChI | InChI=1S/C6H9O9P/c7-1-2(8)4-3(9)5(6(10)14-4)15-16(11,12)13/h2,4,7-9H,1H2,(H2,11,12,13)/t2-,4+/m0/s1 | | InChIKey | MIJPAVRNWPDMOR-ZAFYKAAXSA-N | | SMILES | OC1=C(OP(O)(O)=O)C(=O)O[C@@H]1[C@H](CO)O |
| | L-ASCORBIC ACID 2-MONOPHOSPHATE TRI-CYCLOHEXYLAMMONIUM SALT Usage And Synthesis |
| Uses | L-ascorbic acid 2-phosphate (2-Phospho-L-ascorbic acid) is a long-acting vitamin C derivative that can stimulate collagen formation and expression[1]. L-ascorbic acid 2-phosphate (2-Phospho-L-ascorbic acid) can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs). L-ascorbic acid 2-phosphate increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation[2][3]. | | Definition | ChEBI: L-ascorbic acid 2-phosphate is an aldonolactone phosphate that is the 2-phosphate ester of L-ascorbic acid. It can stimulate collagen formation. It is functionally related to a L-ascorbic acid. It is a conjugate acid of a L-ascorbate 2-phosphate(3-). | | Biological Activity | L-ascorbic acid 2-phosphate is a long-acting vitamin C derivative that stimulates collagen expression and formation. It can be used as a medium to supplement the osteogenic differentiation of human adipose stem cells (hASCs). | | target | IC50: alkaline phosphatase (ALP); collagen formation; runx2A | | IC 50 | Human Endogenous Metabolite | | References | [1] Shima N, et al. Increased proliferation and replicative lifespan of isolated human corneal endothelial cells with L-ascorbic acid 2-phosphate.Invest Ophthalmol Vis Sci. 2011 Nov 7;52(12):8711-7. DOI:10.1167/iovs.11-7592
[2] Kurata S, et al. Epidermal growth factor inhibits transcription of type I collagen genes and production of type I collagen in cultured human skin fibroblasts in the presence and absence of L-ascorbic acid 2-phosphate, a long-acting vitamin C derivative.J Biol Chem. 1991 May 25;266(15):9997-10003. PMID:2033086
[3] Kyllnen L, et al. Effectsofdifferentserumconditionsonosteogenicdifferentiationofhumanadiposestem cellsin vitro.StemCellRes Ther.2013 Feb 15;4(1):17. DOI:10.1186/scrt165 |
| | L-ASCORBIC ACID 2-MONOPHOSPHATE TRI-CYCLOHEXYLAMMONIUM SALT Preparation Products And Raw materials |
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