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| | PROTAC ERRα Degrader-1 Basic information |
| Product Name: | PROTAC ERRα Degrader-1 | | Synonyms: | PROTAC ERRα Degrader-1;1-Piperazineacetamide, 4-[[(4R,5S)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-N-[2-[[(2E)-3-[4-[[2,4-bis(trifluoromethyl)phenyl]methoxy]-3-methoxyphenyl]-2-cyano-1-oxo-2-propen-1-yl]amino]ethyl]-2-oxo- | | CAS: | 2306388-84-9 | | MF: | C54H49Cl2F6N7O8 | | MW: | 1108.91 | | EINECS: | | | Product Categories: | | | Mol File: | 2306388-84-9.mol |  |
| | PROTAC ERRα Degrader-1 Chemical Properties |
| density | 1.38±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | pka | 11.80±0.46(Predicted) | | form | Solid | | color | White to off-white |
| | PROTAC ERRα Degrader-1 Usage And Synthesis |
| Description | ERRα Degrader-1 is a Novel PROTAC Estrogen-related Receptor α (ERRα) Degrader. | | Uses | PROTAC ERRα Degrader-1 comprises a MDM2 ligand binding group, a linker and an estrogen-related receptor alpha (ERRa) binding group. PROTAC ERRα Degrader-1 is an PROTAC estrogen-related receptor alpha (ERRa) degrader[1]. | | IC 50 | ERRα; MDM2 | | References | [1] Peng L, et al. Identification of New Small-Molecule Inducers of Estrogen-related Receptor α (ERRα) Degradation. ACS Med Chem Lett. 2019 Apr 12;10(5):767-772. DOI:10.1021/acsmedchemlett.9b00025 |
| | PROTAC ERRα Degrader-1 Preparation Products And Raw materials |
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