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2-Propenoic acid, 2-cyano-3-(3,4-dihydroxyphenyl)-, (2E)- (9CI)

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2-Propenoic acid, 2-cyano-3-(3,4-dihydroxyphenyl)-, (2E)- (9CI) manufacturers

  • Tyrphostin AG30
  • Tyrphostin AG30 pictures
  • $38.00
  • 2026-07-27
  • CAS:122520-79-0
  • Purity: 99.02%
  • Supply Ability: 10g
2-Propenoic acid, 2-cyano-3-(3,4-dihydroxyphenyl)-, (2E)- (9CI) Basic information
Product Name:2-Propenoic acid, 2-cyano-3-(3,4-dihydroxyphenyl)-, (2E)- (9CI)
Synonyms:2-Propenoic acid, 2-cyano-3-(3,4-dihydroxyphenyl)-, (2E)- (9CI);(E)-2-Cyano-3-(3,4-dihydroxyphenyl)-2-propenoic acid;Tyrphostin AG30(AG30);2-Propenoic acid, 2-cyano-3-(3,4-dihydroxyphenyl)-, (2E)-;(E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enoicaci;2-Propenoic acid, 2-cyano-3-(3,4-dihydroxyphenyl)-, (2E)- (9CI) USP/EP/BP;AG 30 (Tyrphostin AG30);HER1,ErbB-1,Inhibitor,EGFR,Tyrphostin AG30,Epidermal growth factor receptor,Tyrphostin AG 30,AG30,AG-30,AG 30,Tyrphostin AG-30,inhibit
CAS:122520-79-0
MF:C10H7NO4
MW:205.17
EINECS:
Product Categories:ALCOHOL
Mol File:122520-79-0.mol
2-Propenoic acid, 2-cyano-3-(3,4-dihydroxyphenyl)-, (2E)- (9CI) Structure
2-Propenoic acid, 2-cyano-3-(3,4-dihydroxyphenyl)-, (2E)- (9CI) Chemical Properties
Melting point 240 °C
Boiling point 465.6±45.0 °C(Predicted)
density 1.559±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Store in freezer, under -20°C
solubility DMSO: 125 mg/mL (609.25 mM)
pka0.81±0.10(Predicted)
form Yellow solid.
color Light yellow to yellow
Safety Information
MSDS Information
2-Propenoic acid, 2-cyano-3-(3,4-dihydroxyphenyl)-, (2E)- (9CI) Usage And Synthesis
UsesTyrphostin AG30 (AG30) is a potent and selective EGFR tyrosine kinase inhibitor. Tyrphostin AG30 (AG30) selectively inhibits self renewal induction by c-ErbB, and is able to inhibit activation of STAT5 by c-ErbB in primary erythroblasts[1][2].
References[1] Volberg T, et al. The effect of tyrosine-specific protein phosphorylation on the assembly of adherens-type junctions. EMBO J. 1992 May;11(5):1733-42. DOI:10.1002/j.1460-2075.1992.tb05225.x
[2] Wessely O, et al. Distinct roles of the receptor tyrosine kinases c-ErbB and c-Kit in regulating the balance between erythroid cell proliferation and differentiation. Cell Growth Differ. 1997 May;8(5):481-93. PMID:9149900
[3] Banerjee S, et al. Epidermal growth factor induces WISP-2/CCN5 expression in estrogen receptor-alpha-positive breast tumor cells through multiple molecular cross-talks. Mol Cancer Res. 2005 Mar;3(3):151-62. DOI:10.1158/1541-7786.MCR-04-0130
2-Propenoic acid, 2-cyano-3-(3,4-dihydroxyphenyl)-, (2E)- (9CI) Preparation Products And Raw materials
Tag:2-Propenoic acid, 2-cyano-3-(3,4-dihydroxyphenyl)-, (2E)- (9CI)(122520-79-0) Related Product Information
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