TYRPHOSTIN AG 835 manufacturers
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| | TYRPHOSTIN AG 835 Basic information |
| Product Name: | TYRPHOSTIN AG 835 | | Synonyms: | AG 835;ALPHA-CYANO-(+)-(S)-N-(ALPHA-PHENETHYL)-(3,4-DIHYDROXY)CINNAMIDE;(S)-(E)-2-CYANO-3-(3',4'-DIHYDROXYPHENYL)-N-(1-PHENYLETHYL)-2-PROPENAMIDE;(+)-(S)-N-(ALPHA-METHYLBENZYL)-3,4-DIHYDROXY-BENZYLIDENECYANOACETAMIDE;TYRPHOSTIN B44, (+) ENANTIOMER;TYRPHOSTIN AG 835;TYRPHOSTIN B50;TYRPHOSTIN B50(+) | | CAS: | 133550-37-5 | | MF: | C18H16N2O3 | | MW: | 308.33 | | EINECS: | | | Product Categories: | Protein Kinase | | Mol File: | 133550-37-5.mol |  |
| | TYRPHOSTIN AG 835 Chemical Properties |
| Melting point | 146 °C | | Boiling point | 603.0±55.0 °C(Predicted) | | density | 1.299±0.06 g/cm3(Predicted) | | storage temp. | −20°C | | solubility | DMSO or ethanol: soluble | | form | powder to crystal | | pka | 8.81±0.10(Predicted) | | color | Light yellow to Amber to Dark green |
| Safety Statements | 22-24/25 | | WGK Germany | 3 | | HS Code | 2926.90.4801 |
| | TYRPHOSTIN AG 835 Usage And Synthesis |
| Uses | Tyrphostin B44, (+) enantiomer is an EGFR kinase inhibitor. | | Biological Activity | Epidermal growth factor receptor (EGFR) kinase inhibitor (IC 50 = 0.86 μ M). Slightly less active than the (-) enantiomer ((R)-(E)-2-Cyano-3-(3',4'-dihydroxyphenyl)-N-(1-phenylethyl)-2-propenamide ). |
| | TYRPHOSTIN AG 835 Preparation Products And Raw materials |
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