N2-Methylguanosine

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N2-Methylguanosine Basic information
Product Name:N2-Methylguanosine
Synonyms:2-Methylguanosine;9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-methylamino-3H-purin-6-one;N-Methylguanosine;Guanosine, N-methyl-;m2G;9-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-(methylamino)-1H-purin-6(9H)-one;N2-Methylguanosine,RNA-modified nucleoside m2G;N2-Methylguanosine,inhibit,Nucleoside Antimetabolite/Analog,N-2-Methylguanosine,Inhibitor,N2Methylguanosine,Endogenous Metabolite,N2 Methylguanosine
CAS:2140-77-4
MF:C11H15N5O5
MW:297.27
EINECS:
Product Categories:Biochemicals and Reagents;Nucleoside Analogs;Nucleosides, Nucleotides, Oligonucleotides
Mol File:2140-77-4.mol
N2-Methylguanosine Structure
N2-Methylguanosine Chemical Properties
Melting point 233 °C (decomp)(Solv: water (7732-18-5))
density 2.00±0.1 g/cm3(Predicted)
storage temp. −20°C
solubility DMSO : 7.69 mg/mL (25.87 mM; Need ultrasonic)|
pka9.87±0.20(Predicted)
form Solid
color White to off-white
PH2.3;9.7
Water Solubility Water : 1 mg/mL (3.36 mM; ultrasonic and warming and heat to 80°C)
λmax259 (pH 1);253 (pH 7);258 (pH 13)
InChIInChI=1S/C11H15N5O5/c1-12-11-14-8-5(9(20)15-11)13-3-16(8)10-7(19)6(18)4(2-17)21-10/h3-4,6-7,10,17-19H,2H2,1H3,(H2,12,14,15,20)/t4-,6-,7-,10-/m1/s1
InChIKeySLEHROROQDYRAW-KQYNXXCUSA-N
SMILESOC[C@H]1O[C@@H](N2C3=C(C(NC(=N3)NC)=O)N=C2)[C@H](O)[C@@H]1O
Safety Information
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
N2-Methylguanosine Usage And Synthesis
DefinitionChEBI: Guanosine with the hydrogen on the amine at position N-2 substituted with a methyl group.
N2-Methylguanosine Preparation Products And Raw materials
Tag:N2-Methylguanosine(2140-77-4) Related Product Information
N-Acetyl-5'-O-(4,4-dimethoxytrityl)-2'-O-methylguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite 2'-C-Methylguanosine 2'-O-METHYLGUANOSINE N2-Benzoyl-D-guanosine 7,8-Dihydro-7-methylguanosine 1-Methylguanosine N2-Methylguanosine 2-(Dimethylamino)guanosine BIOTIN-11-GTP 2'-O-methylguanosine 5'-monophosphate 7-methylguanosine triphosphate 6-O-Methyl Guanosine N2,2'-O-DIBUTYRYLGUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALT 5'-DMT-RIBO GUANOSINE (N-IBU) 8-methylguanosine 2'-O-methylguanosine 5'-triphosphate beta-Phenyl-1,N2-ethenoguanosine-3',5'-cyclic monophosphate sodium salt N2-(2-Methylpropanoyl)-guanosine