|
|
| | Sulforhodamine 101 Basic information |
| Product Name: | Sulforhodamine 101 | | Synonyms: | 8-(2,4-DISULFOPHENYL)-2,3,5,6,11,12,14,15-OCTAHYDRO-1H,4H,10H,13H-DIQUINOLIZINO[9,9A,1-BC:9',9A',1-HI]XANTHENE;SULFORHODAMINE 640;Sulforhodamine 101 (free acid);SULFORHODAMINE 101 ACID;1H,5H,11H,15H-Xantheno[2,3,4-ij:5,6,7-i'j']diquinolizin-18-ium,9-(2,4-disulfophenyl)-2,3,6,7,12,13,16,17-octahydro-, inner salt;TEXAS RED;1h,5h,11h,15h-xantheno[2,3,4-ij:5,6,7-i’j’]diquinolizin-18-ium,9-(2,4-disulfop;henyl)-2,3,6,7,12,13,16,17-octahydro-,hydroxide,innersalt | | CAS: | 60311-02-6 | | MF: | C31H30N2O7S2 | | MW: | 606.71 | | EINECS: | 262-159-4 | | Product Categories: | S;Stains and Dyes;Stains&Dyes, A to;FLUOROPHORES | | Mol File: | 60311-02-6.mol |  |
| | Sulforhodamine 101 Chemical Properties |
| Melting point | >300°C | | density | 1.1982 (rough estimate) | | refractive index | 1.6900 (estimate) | | storage temp. | Inert atmosphere,Room Temperature | | solubility | methanol: soluble1mg/mL | | form | powder | | color | Dark Green | | Appearance | Green to Dark Green Solid | | ε(extinction coefficient) | ≥105000 at 573-579nm in ethanol | | λmax | 579nm(CHCl3)(lit.) | | BRN | 3582548 | | Major Application | diagnostic assay manufacturing
hematology
histology | | InChIKey | COIVODZMVVUETJ-UHFFFAOYSA-N | | SMILES | S(C1C=C(S(O)(=O)=O)C=CC=1C1C2=CC3CCCN4CCCC(C=34)=C2[O+]=C2C3CCCN4CCCC(C=34)=CC=12)([O-])(=O)=O | | CAS DataBase Reference | 60311-02-6 | | EPA Substance Registry System | 1H,5H,11H,15H-Xantheno[2,3,4-ij:5,6,7-i'j']diquinolizin-18-ium, 9-(2,4-disulfophenyl)-2,3,6,7,12,13,16,17-octahydro-, inner salt (60311-02-6) |
| Safety Statements | 22-24/25 | | WGK Germany | 3 | | F | 8 | | TSCA | TSCA listed | | HS Code | 32049090 | | Storage Class | 11 - Combustible Solids |
| | Sulforhodamine 101 Usage And Synthesis |
| Description | Sulforhodamine 101 is a nonfixable red fluorescent dye (excitation max: 586 nm; emission max: 605 nm) that can be used as a specific marker for astrocytes and an activity-dependent probe for monitoring regulated exocytosis. It has been reported to induce long-term potentiation of intrinsic neuronal excitability and a long-lasting increase in evoked excitatory postsynaptic potentials in CA1 pyramidal neurons in hippocampal slices. | | Chemical Properties | green to dark green crystalline powder | | Uses | A red-emitting flurophore used to label astrocytes. | | Uses | Sulforhodamine 101 is a red fluorescent dye used in the calcium imaging methods in neurophysiological experiments.Dyes and metabolites. | | Application | Used as a coloring agent and dye. | | in vivo | In vivo, epileptic activity can be induced by intra-hippocampal injection of small volumes of 10 μM Texas Red or topical application of 100 μM[1]. | | storage | +4°C | | References | [1] AXEL NIMMERJAHN. Sulforhodamine 101 as a specific marker of astroglia in the neocortex in vivo[J]. Nature Methods, 2004, 1 1: 31-37. DOI: 10.1038/nmeth706
[2] J. KANG . Sulforhodamine 101 induces long-term potentiation of intrinsic excitability and synaptic efficacy in hippocampal CA1 pyramidal neurons[J]. Neuroscience, 2010, 169 4: Pages 1601-1609. DOI: 10.1016/j.neuroscience.2010.06.020 | | Excitation / Emission Maximum | 586 nm/605 nm |
| | Sulforhodamine 101 Preparation Products And Raw materials |
|