TCO-PEG3-Amine

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TCO-PEG3-Amine Suppliers list
Company Name: Jinan elephant international trading co., LTD  
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Email: 13006575422@163.com
Company Name: Xi'an Confluore Biological Technology Co., Ltd.  
Tel: +86-156-80926068 +86-15680926068
Email: 1924344760@qq.com
Company Name: TargetMol Chemicals Inc.  
Tel: +1-781-999-5354; +1-00000000000
Email: marketing@targetmol.com
Company Name: Henan Weituxi Chemical Technology Co., Ltd.  
Tel: 0371-63284658 18135795563
Email: 3905209149@qq.com
Company Name: Shaanxi Xinyan Bomei Biotechnology Co., Ltd.  
Tel: 13892832556
Email: 2440688701@qq.com

TCO-PEG3-Amine manufacturers
TCO-PEG3-Amine Basic information
Product Name:TCO-PEG3-Amine
Synonyms:TCO-PEG3-Amine;TCO-C3-PEG3-C3-amine;(4E)-TCO-C3-PEG3-C3-amine;TCO-PEG3-C3-amine
CAS:2028288-77-7
MF:C19H36N2O5
MW:372.5
EINECS:
Product Categories:peg
Mol File:2028288-77-7.mol
TCO-PEG3-Amine Structure
TCO-PEG3-Amine Chemical Properties
Boiling point 506.5±50.0 °C(Predicted)
density 1.06±0.1 g/cm3(Predicted)
pka12.38±0.46(Predicted)
Safety Information
MSDS Information
TCO-PEG3-Amine Usage And Synthesis
DescriptionTCO-PEG3-amine is a click chemistry crosslinking reagent. It can be used to derivatize NHS activated esters through a stable amide bond or carboxyl groups in the presence of of activators (e.g. EDC, or HATU). TCO enable click chemistry with tetrazine. PEG spacer improves water solubility.
UsesTCO-C3-PEG3-C3-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50PEGs
References[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
TCO-PEG3-Amine Preparation Products And Raw materials
Tag:TCO-PEG3-Amine(2028288-77-7) Related Product Information
BDP fl-PEG4-(4E)-TCO Gly-PEG3-(4E)-TCO (4E)-TCO-PEG3-amine (2E)-TCO-PNB ester TCO-PEG4-NHS ester (4E)-TCO-PEG4-DBCO (4E)-TCO-amine TCO-PEG4-Acid trans-Cyclooctene-maleimide Sulfo-Cy5-(4E)-TCO (4E)-TCO-PEG4-amine TCO-carbonate TCO/E- active ester (p-NPE) / equatorial