Ald-PEG4-t-butyl ester

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Ald-PEG4-t-butyl ester manufacturers

Ald-PEG4-t-butyl ester Basic information
Product Name:Ald-PEG4-t-butyl ester
Synonyms:CHO-PEG4-COOtBu;CHOCH2-PEG4-COOtBu;Ald-PEG4-t-butyl ester;Ald-CH2-PEG4-CH2CH2COOtBu;ALD-CH2-PEG4-T-BUTYL ESTER;Ald-CH2-PEG4-Boc;4,7,10,13-Tetraoxapentadecanoic acid, 15-oxo-, 1,1-dimethylethyl ester;tert-Butyl 1-oxo-3,6,9,12-tetraoxapentadecan-15-oate
CAS:1415329-20-2
MF:C15H28O7
MW:320.38
EINECS:
Product Categories:peg
Mol File:1415329-20-2.mol
Ald-PEG4-t-butyl ester Structure
Ald-PEG4-t-butyl ester Chemical Properties
Boiling point 401.7±35.0 °C(Predicted)
density 1.059±0.06 g/cm3(Predicted)
storage temp. 2-8°C, stored under nitrogen
form Viscous Liquid
color Colorless to light yellow
Safety Information
MSDS Information
Ald-PEG4-t-butyl ester Usage And Synthesis
DescriptionAld-CH2-PEG4-t-butyl ester is a PEG linker that is reactive with aminooxy-containing molecules. The t-butyl ester can be removed under acidic conditions for further conjugation.
UsesAld-CH2-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50PEGs; Alkyl/ether
References[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Ald-PEG4-t-butyl ester Preparation Products And Raw materials
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