- Fmoc-Dab(Boc)-OH
-
- $0.00/ kg
-
2026-04-01
- CAS:125238-99-5
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 1T
- FMOC-DAB(BOC)-OH
-
- $69.00 / 5g
-
2026-04-01
- CAS:125238-99-5
- Min. Order: 5g
- Purity: 0.98
- Supply Ability: 25kg
- FMOC-DAB(BOC)-OH
-
- $0.00 / 1kg
-
2025-04-04
- CAS:125238-99-5
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 1Ton
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| | FMOC-DAB(BOC)-OH Basic information |
| Product Name: | FMOC-DAB(BOC)-OH | | Synonyms: | N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-GAMMA-T-BUTYLOXYCARBONYL-L-2,4-DIAMINOBUTYRIC ACID;N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-GAMMA-TERT-BUTYLOXYCARBONYL-L-2,4-DIAMINOBUTYRIC ACID;NA-FMOC-NG-BOC-(S)-2,4-DIAMINOBUTYRIC ACID;N-Fmoc-N-Boc-L-2,4-diaminobutyric acid;L-2,4-Diaminobutanoic acid, N4-BOC, N2-FMOC protected;FMOC-4-BOC-L-2,4-DIAMINOBUTYRIC ACID;FMOC-L-2,4-DIAMINOBUTYRIC ACID(BOC);FMOC-L-DAB(BOC) | | CAS: | 125238-99-5 | | MF: | C24H28N2O6 | | MW: | 440.49 | | EINECS: | 1533716-785-6 | | Product Categories: | amino acid;Amino Acids;Unusual amino acids | | Mol File: | 125238-99-5.mol |  |
| | FMOC-DAB(BOC)-OH Chemical Properties |
| Melting point | 111-113℃ | | Boiling point | 670.9±55.0 °C(Predicted) | | density | 1.243±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO (Slightly), Methanol (Slightly) | | pka | 3.79±0.10(Predicted) | | form | Solid | | color | White to Off-White | | Optical Rotation | [α]20/546 14.5±1°, c = 1% in methanol | | Water Solubility | Slightly soluble in water. | | BRN | 6250328 | | Major Application | peptide synthesis | | InChIKey | LIWKOFAHRLBNMG-FQEVSTJZSA-N | | SMILES | C(O)(=O)[C@@H](NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O)CCNC(OC(C)(C)C)=O |
| Hazard Codes | Xi | | WGK Germany | 3 | | F | 10 | | HS Code | 2924 29 70 | | HazardClass | IRRITANT | | Storage Class | 11 - Combustible Solids |
| | FMOC-DAB(BOC)-OH Usage And Synthesis |
| Chemical Properties | White powder | | Uses | Fmoc-Dab(Boc)-OH, | | reaction suitability | reaction type: Fmoc solid-phase peptide synthesis | | Synthesis | The general procedure for the synthesis of N-Fmoc-N'-Boc-L-2,4-diaminobutyric acid from di-tert-butyl dicarbonate and Fmoc-L-2,4-diaminobutyric acid was as follows: 50 g (146.8 mmol) of Fmoc-L-2,4-diaminobutyric acid was suspended in 700 mL of a mixed solvent of acetone and water (1:1, v/v/v/v/v) at 0-10 °C. 38.4 g (176 mmol) of di-tert-butyl dicarbonate was slowly added. Subsequently, the pH of the reaction system was adjusted to 7.5-8 with 0.5 N NaOH solution.After 4 h of reaction, 56 g of N-fluorenylmethoxycarbonyl-N'-tert-butoxycarbonyl-L-2,4-diaminobutyric acid was obtained by the treatment in a yield of 86.62% and a purity of 99.4% by HPLC. The structure of the product was confirmed by IR and NMR spectra as detailed in Figures 3 and 4 in the literature. | | References | [1] Patent: CN105348147, 2016, A. Location in patent: Paragraph 0020
[2] Bulletin of the Chemical Society of Japan, 2004, vol. 77, # 10, p. 1915 - 1924
[3] European Journal of Medicinal Chemistry, 1995, vol. 30, # 2, p. 115 - 122 |
| | FMOC-DAB(BOC)-OH Preparation Products And Raw materials |
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