- Cyclohexylboronic acid
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- $1.00
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2019-07-06
- CAS:4441-56-9
- Min. Order: 1KG
- Purity: 97%-99%
- Supply Ability: 1kg;5kg;100kg
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| | Cyclohexylboronic acid Basic information |
| | Cyclohexylboronic acid Chemical Properties |
| Melting point | 122-123 °C | | Boiling point | 252.4±23.0 °C(Predicted) | | density | 1.00±0.1 g/cm3(Predicted) | | storage temp. | Inert atmosphere,Store in freezer, under -20°C | | solubility | soluble in Methanol | | pka | 10.47±0.20(Predicted) | | form | powder | | color | White to Orange to Green | | Water Solubility | 25 g/L | | InChI | InChI=1S/C6H13BO2/c8-7(9)6-4-2-1-3-5-6/h6,8-9H,1-5H2 | | InChIKey | XDRVAZAFNWDVOE-UHFFFAOYSA-N | | SMILES | C1CCCCC1B(O)O | | CAS DataBase Reference | 4441-56-9(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 37/39-26 | | WGK Germany | 3 | | RTECS | GU7171000 | | HazardClass | IRRITANT | | HS Code | 29319090 | | Storage Class | 11 - Combustible Solids |
| | Cyclohexylboronic acid Usage And Synthesis |
| Chemical Properties | White to light yellow crystal powde | | Uses | Reactant involved in:• ;HF-free synthesis of tetrabutylammonium trifluoroborates1• ;Cross-coupling with aromatic amines2• ;Suzuki cross-coupling reactions3• ;Arylation and alkylation of diphenylisoxazole4 | | Uses | suzuki reaction | | Uses | Reactant involved in:
- HF-free synthesis of tetrabutylammonium trifluoroborates
- Cross-coupling with aromatic amines
- Suzuki cross-coupling reactions
- Arylation and alkylation of diphenylisoxazole
| | Synthesis | Diisopropylaminoborane (2.4 mL, 2.4 mmol, 1.2 eq.) was added to a 50 mL round-bottomed flask fitted with a magnetic stir bar and fitted with a rubber septum. O-tolylmagnesium bromide (2 mL, 2.0 mmol, 1 eq.) was added dropwise over 5 min via syringe while stirring (ice bath) at 0C. After 1 hr, with the reaction still on ice, 3 M HCl (5 mL) was added dropwise over 5 min and stirred for 30 min. The reaction mixture was then refluxed for 15 min. After refluxing, the solution was transferred to a partition funnel and extracted with Et2O (2 15 mL). The organic layers were combined and extracted with 1 M HCl (4 15 mL), dried with anhydrous MgSO4 and evaporated in vacuum (25C, 1 Torr). A white powder cyclohexylboronic acid was obtained; 97% yield (0.497 g). |
| | Cyclohexylboronic acid Preparation Products And Raw materials |
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