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| | Propargyl-PEG5-tetra-Ac-beta-D-galactose Basic information |
| Product Name: | Propargyl-PEG5-tetra-Ac-beta-D-galactose | | Synonyms: | Propargyl-PEG5-tetra-Ac-beta-D-galactose;Propargyl-PEG4-tetra-Ac-beta-D-galactose;β-D-Galactopyranoside, 3,6,9,12-tetraoxapentadec-14-yn-1-yl, 2,3,4,6-tetraacetate;(2R,3R,4S,5S,6R)-2-((3,6,9,12-Tetraoxapentadec-14-yn-1-yl)oxy)-6-(acetoxymethyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate;β-Gal-PEG4-Alkyne tetraacetate | | CAS: | 1397682-61-9 | | MF: | C25H38O14 | | MW: | 562.57 | | EINECS: | | | Product Categories: | | | Mol File: | 1397682-61-9.mol |  |
| | Propargyl-PEG5-tetra-Ac-beta-D-galactose Chemical Properties |
| Boiling point | 583.7±50.0 °C(Predicted) | | density | 1.23±0.1 g/cm3(Predicted) |
| | Propargyl-PEG5-tetra-Ac-beta-D-galactose Usage And Synthesis |
| Description | Propargyl-PEG5-tetra-Ac-beta-D-galactose is a Click Chemistry-ready crosslinker containing a propargyl group and beta-D-galactose. The propargyl groups can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield stable triazole linkages. D-galactose increases solubility in aqueous media and a the selectivity of the PEGlation reaction. | | Uses | Propargyl-PEG4-tetra-Ac-beta-D-galactose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Propargyl-PEG5-tetra-Ac-beta-D-galactose Preparation Products And Raw materials |
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