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| | N-Hydroxyurethane Basic information |
| | N-Hydroxyurethane Chemical Properties |
| Boiling point | 113-116 °C3 mm Hg(lit.) | | density | 1.3895 (rough estimate) | | refractive index | n20/D 1.445(lit.) | | Fp | >230 °F | | storage temp. | -20°C | | solubility | Diethyl Ether, Dimethyl Sulfoxide, Water | | pka | 9.30±0.23(Predicted) | | form | Oil | | color | Yellow | | BRN | 1747529 | | InChI | 1S/C3H7NO3/c1-2-7-3(5)4-6/h6H,2H2,1H3,(H,4,5) | | InChIKey | VGEWEGHHYWGXGG-UHFFFAOYSA-N | | SMILES | CCOC(=O)NO | | CAS DataBase Reference | 589-41-3(CAS DataBase Reference) | | NIST Chemistry Reference | Carbamic acid, hydroxy-, ethyl ester(589-41-3) |
| Risk Statements | 36/37/38 | | Safety Statements | 26-36/37/39 | | WGK Germany | 2 | | RTECS | FB1750000 | | HS Code | 2928009090 | | Storage Class | 10 - Combustible liquids | | Toxicity | LD50 intraperitoneal in rat: 800mg/kg |
| | N-Hydroxyurethane Usage And Synthesis |
| Chemical Properties | Yellow Oil | | Uses | Hydroxyurethane is a metabolite of carcinogenic Urethane (U825300). | | Uses | Reactant involved in:
- Synthesis of molecules used for intermolecular Sharpless aminohydroxylation reactions
- Intermolecular ortho-C-H amidation of anilides
- Cinchona alkaloid-catalyzed asymmetric cycloaddition
- Allylic arylation
| | Biochem/physiol Actions | N-Hydroxyurethane causes the chromosomal fragmentation at millimolar concentrations and cell toxicity in cultured normal human leukocytes. |
| | N-Hydroxyurethane Preparation Products And Raw materials |
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