- Dimethyl itaconate
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2026-10-13
- CAS:617-52-7
- Min. Order: 1KG
- Purity: 98%min
- Supply Ability: 30tons/month
- Dimethyl itaconate
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2026-06-30
- CAS:617-52-7
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 10000KGS
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| | Dimethyl itaconate Basic information |
| Product Name: | Dimethyl itaconate | | Synonyms: | Methyl 4-methoxy-2-methylene-4-oxobutanoate;1-Propene-2,3-dicarboxylic acid dimethyl ester;2-Methylenebutanedioic acid dimethyl ester;Dimethyl 1-propene-2,3-dicarboxylate;Dimethyl itaconate,97%;Dimethyl 2-methylidenebutane-1,4-dioate, Dimethyl itaconate;DiMethyl itaconate, 97%, stabilized;Dimethyl itaconate 97% | | CAS: | 617-52-7 | | MF: | C7H10O4 | | MW: | 158.15 | | EINECS: | 210-519-6 | | Product Categories: | C6 to C7;Esters;C7 to C8;Carbonyl Compounds;Ketones;bc0001 | | Mol File: | 617-52-7.mol |  |
| | Dimethyl itaconate Chemical Properties |
| Melting point | 37-41 °C (lit.) | | Boiling point | 208 °C (lit.) | | density | 1.124 g/mL at 25 °C (lit.) | | vapor pressure | 4.05Pa at 20℃ | | refractive index | 1.4457 (estimate) | | Fp | 213 °F | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) | | form | Crystalline Low Melting Mass or Liquid | | Specific Gravity | 1.124 | | color | White | | Water Solubility | slightly soluble | | BRN | 386674 | | Cosmetics Ingredients Functions | HAIR CONDITIONING
SKIN PROTECTING
SKIN CONDITIONING - MISCELLANEOUS
ANTIOXIDANT | | InChI | 1S/C7H10O4/c1-5(7(9)11-3)4-6(8)10-2/h1,4H2,2-3H3 | | InChIKey | ZWWQRMFIZFPUAA-UHFFFAOYSA-N | | SMILES | COC(=O)CC(=C)C(=O)OC | | LogP | 0.86 at 25℃ | | CAS DataBase Reference | 617-52-7(CAS DataBase Reference) | | NIST Chemistry Reference | Butanedioic acid, methylene-, dimethyl ester(617-52-7) | | EPA Substance Registry System | Butanedioic acid, 2-methylene-, 1,4-dimethyl ester (617-52-7) |
| Safety Statements | 24/25 | | WGK Germany | 3 | | F | 3 | | TSCA | TSCA listed | | HS Code | 29171900 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Skin Irrit. 2
Skin Sens. 1B |
| | Dimethyl itaconate Usage And Synthesis |
| Chemical Properties | white crystalline low melting mass or liquid | | Uses | Dimethyl Itaconate is a chemical reagent used in the synthesis of functionalized 2-isoxazolines used in fragment-based drug discovery. | | Uses | Dimethyl itaconate may be used in functionalization of isotactic poly(propylene). It was used in crosslinking of polyesters: poly(isosorbide itaconate)and poly(isosorbide itaconate-co-succinate). | | Uses | Dimethyl itaconate can be used for the rhodium catalyzed asymmetric hydrogenation of (S)-dimethyl-2-methylsuccinate and (R)-methyl succinic acid dimethyl ester. | | General Description | Dimethyl itaconate undergoes enantioselective Rh(I)-catalyzed hydrogenation which can be enhanced by appropriate choice of substituents on aromatic ring of (1,2-diarylphosphinoxy)cyclohexane. | | Flammability and Explosibility | Non flammable | | Synthesis | 1. Itaconic acid, methanol and catalyst were mixed in a certain ratio and transferred to a 100 mL autoclave. 2. The reaction mixture was continuously stirred at 120 °C. 3. Optimization of the reaction conditions was carried out by adjusting the parameters such as the molar ratio of methanol to itaconic acid, the catalyst dosage and the reaction time. 4. Upon completion of the reaction, the catalyst was separated and recovered through a filtration operation. | | Purification Methods | Crystallise the ester from MeOH by cooling to -78o. [Beilstein 2 IV 2229.] | | References | [1] Journal of Molecular Catalysis A: Chemical, 2013, vol. 368-369, p. 24 - 30
[2] Heterocycles, 1988, vol. 27, # 8, p. 1887 - 1898
[3] Tetrahedron Letters, 2015, vol. 56, # 27, p. 4119 - 4123
[4] Chemistry and physics of lipids, 2002, vol. 120, # 1-2, p. 9 - 20
[5] Russian Chemical Bulletin, 2005, vol. 54, # 2, p. 348 - 353 |
| | Dimethyl itaconate Preparation Products And Raw materials |
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