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Fmoc-D-leucine

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Fmoc-D-leucine Suppliers list
Company Name: Chengdu Maidisen Biotechnology Co., Ltd.  Gold
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Fmoc-D-leucine manufacturers

  • Fmoc-D-Leu-OH
  • Fmoc-D-Leu-OH pictures
  • 2026-09-11
  • CAS:114360-54-2
  • Min. Order: 1kg
  • Purity: 98%
  • Supply Ability: 1T
  • Fmoc-D-Leu-OH
  • Fmoc-D-Leu-OH pictures
  • 2026-09-11
  • CAS:114360-54-2
  • Min. Order: 1KG
  • Purity: 98%min
  • Supply Ability: 500kgs
Fmoc-D-leucine Basic information
Synthesis
Product Name:Fmoc-D-leucine
Synonyms:FMOC-D-BETA-LEU-OH;FMOC-D-LEUCINE;9-FLUORENYLMETHOXYCARBONYL-D-LEUCINE;FMOC-D-LEU-OH 99+%;n-fmoc-d-leucine;N-9-FLUORENYLMETHYLOXYCARBONYL-D-LEUCINE(FMOC-D-LEU-OH);N-(9-FLUORENYLMETHOXYCARBONYL)-D-LEUCINE;N-9-FLUORENYLMETHYLOXYCARBONYL-D-LEUCINE
CAS:114360-54-2
MF:C21H23NO4
MW:353.41
EINECS:252-662-7
Product Categories:Leucine [Leu, L];Fmoc-Amino Acids and Derivatives;Amino Acids (N-Protected);Biochemistry;Fmoc-Amino Acids;Fmoc-Amino acid series;Fluorenes, Flurenones;Amino Acids
Mol File:114360-54-2.mol
Fmoc-D-leucine Structure
Fmoc-D-leucine Chemical Properties
Melting point 155°C
Boiling point 559.8±33.0 °C(Predicted)
density 1+-.0.06 g/cm3(Predicted)
refractive index 25 ° (C=1, DMF)
storage temp. 2-8°C
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka3.91±0.21(Predicted)
form powder to crystal
color White to Almost white
Optical RotationConsistent with structure
Water Solubility Insoluble in water.
Major Applicationpeptide synthesis
InChIInChI=1S/C21H23NO4/c1-13(2)11-19(20(23)24)22-21(25)26-12-18-16-9-5-3-7-14(16)15-8-4-6-10-17(15)18/h3-10,13,18-19H,11-12H2,1-2H3,(H,22,25)(H,23,24)/t19-/m1/s1
InChIKeyCBPJQFCAFFNICX-LJQANCHMSA-N
SMILESC(O)(=O)[C@@H](CC(C)C)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
CAS DataBase Reference114360-54-2(CAS DataBase Reference)
Safety Information
Safety Statements 22-24/25
WGK Germany 3
F 10
HS Code 29224999
Storage Class11 - Combustible Solids
MSDS Information
ProviderLanguage
SigmaAldrich English
Fmoc-D-leucine Usage And Synthesis
Synthesis

FMOC-D-leucine is prepared by reacting 9-fluorenemethoxycarbonyl chloride with leucine in the presence of a base. This method is simple to operate, has mild reaction conditions, high yield, and wide applicability. The synthetic reaction formula of FMOC-D-leucine is shown in the figure below:

Synthesis of 114360-54-2

Chemical PropertiesWhite powder
UsesA convergent synthesis of the proposed structure of (+)-pestalazine B has been achieved in 4 steps using the N-alkylation of an unprotected tryptophan diketopiperazine with a 3a-bromopyrrolidinoindoline where the condensation between L-tryptophan methyl ester and N-Fmoc-D-leucine in the presence of EDC as coupling agent afforded the corresponding L-Trp-D-Leu dipeptide.
DefinitionChEBI: Fmoc-D-Leu-OH is a leucine derivative.
reaction suitabilityreaction type: Fmoc solid-phase peptide synthesis
Fmoc-D-leucine Preparation Products And Raw materials
Tag:Fmoc-D-leucine(114360-54-2) Related Product Information
N-CARBOBENZOXY-DL-LEUCINE D-2-Amino-4-methylpentanoic acid Fmoc-Phe-OH L-Leucine Fmoc-Lys(Boc)-OH Nalpha-Fmoc-Ndelta-trityl-L-glutamine Fmoc-Asp(OtBu)-OH L-Fmoc-Aspartic acid alpha-tert-butyl ester 9-Fluorenylmethyl chloroformate 1-(4-BROMOPHENYL)CYCLOBUTANAMINE (HYDROCHLORIDE) Fmoc-OSu L-tert-Leucine FMOC-D-GLA(OTBU)2-OH Fmoc Fmoc-N-methyl-D-leucine Fmoc-D-Cha-OH Fmoc-D-cyclopropylalanine Fmoc-Leu-OH