5-Methoxy-2-nitrobenzonitrile

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5-Methoxy-2-nitrobenzonitrile manufacturers

5-Methoxy-2-nitrobenzonitrile Basic information
Product Name:5-Methoxy-2-nitrobenzonitrile
Synonyms:3-Cyano-4-nitroanisole, 2-Cyano-4-methoxynitrobenzene;3-Cyano-4-nitroanisole;Benzonitrile, 5-methoxy-2-nitro-;5-Methoxy-2-nitrobenzonitrile
CAS:38469-84-0
MF:C8H6N2O3
MW:178.14
EINECS:
Product Categories:
Mol File:38469-84-0.mol
5-Methoxy-2-nitrobenzonitrile Structure
5-Methoxy-2-nitrobenzonitrile Chemical Properties
Melting point 96 °C
Boiling point 352.2±32.0 °C(Predicted)
density 1.32±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
AppearanceLight brown to yellow Solid
Safety Information
HS Code 2926907090
MSDS Information
5-Methoxy-2-nitrobenzonitrile Usage And Synthesis
Synthesis
5-METHOXY-2-NITROBENZAMIDE

41994-92-7

5-METHOXY-2-NITROBENZONITRILE

38469-84-0

Step 2: Synthesis of 5-methoxy-2-nitrobenzonitrile To a 100 mL round bottom flask was added 5-methoxy-2-nitrobenzamide (2.1 g, 0.01 mol), trifluoroacetic anhydride (2.2 mL), triethylamine (2.9 mL) and dichloromethane (30 mL). The reaction mixture was stirred at room temperature for 1 hour. After completion of the reaction, the reaction mixture was washed with distilled water (30 mL × 2). The organic layer was separated and dried over anhydrous sodium sulfate and subsequently concentrated under reduced pressure to give 1.75 g (92% yield) of white solid product. Mass spectrometry (MS) showed m/z: 179 ([M + H]+).

References[1] Patent: US2010/120741, 2010, A1. Location in patent: Page/Page column 59
5-Methoxy-2-nitrobenzonitrile Preparation Products And Raw materials
Raw materialsMethanol-->5-Methoxy-2-nitrobenzamide-->5-Fluoro-2-nitrobenzonitrile-->Triethylamine-->Trifluoroacetic anhydride-->Dichloromethane-->5-Methoxy-2-nitrobenzoic acid
Tag:5-Methoxy-2-nitrobenzonitrile(38469-84-0) Related Product Information
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