- BAPTA
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- $2.20
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2026-08-25
- CAS:85233-19-8
- Min. Order: 1kg
- Purity: 99%min
- Supply Ability: 100kg
- BAPTA
-
- $90.00
-
2026-05-11
- CAS:85233-19-8
- Purity: 97.21%
- Supply Ability: 10g
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| Product Name: | BAPTA | | Synonyms: | BAPTA;ETHYLENEDIOXYBIS(O-PHENYLENENITRILO)TETRAACETIC ACID;1,2-BIS-(O-AMINOPHENOXY)-ETHANE-N,N,N',N'-TETRAACETIC ACID;BAPTA, Ethylenedioxybis(o-phenylenenitrilo)tetraacetic acid, 2,2μ-(Ethylenedioxy)dianiline-N,N,Nμ,Nμ-tetraacetic acid;BAPTA, Ethylenedioxybis(o-phenylenenitrilo)tetraacetic acid;1,2-BIS(2-AMINOPHENOXY)-ETHANE-N,N,N',N'- TETRAACETIC ACID 97%;2,2',2'',2'''-[Ethylenebisoxybis(2,1-phenylenenitrilo)]tetrakisacetic acid;Ethylenebis(oxy-2,1-phenylenenitrilo)tetraacetic acid | | CAS: | 85233-19-8 | | MF: | C22H24N2O10 | | MW: | 476.43 | | EINECS: | | | Product Categories: | Aromatic;Amines;Aromatics;Chelating Agents & Ligands;Fluorescent Labels & Indicators | | Mol File: | 85233-19-8.mol |  |
| | BAPTA Chemical Properties |
| Melting point | 177-179 °C | | Boiling point | 575.89°C (rough estimate) | | density | 1.4482 (rough estimate) | | refractive index | 1.6500 (estimate) | | RTECS | MC0423000 | | storage temp. | 2-8°C | | solubility | Soluble in dimethyl sulfoxide | | form | Powder | | pka | 1.40±0.10(Predicted) | | color | White to off-white | | Appearance | Solid Powder | | Water Solubility | Soluble in water and sodium bicarbonate. | | λmax | 209 nm, 254 nm, 203 nm, 274 nm | | Merck | 14,957 | | BRN | 5192406 | | Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month. | | Biological Applications | Calcium indicators; zinc indicators; treating acute cell death,cerebral infarction,myocardial infarction,hepatonecrosis,kidney ischemic necrosis,necrotizing pancreatitis,amyloidosis,atherosclerosis,diseases characteriz | | InChIKey | FTEDXVNDVHYDQW-UHFFFAOYSA-N | | SMILES | OC(=O)CN(CC(O)=O)c1ccccc1OCCOc2ccccc2N(CC(O)=O)CC(O)=O | | CAS DataBase Reference | 85233-19-8(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36-37/39 | | WGK Germany | 3 | | HS Code | 29225090 | | Storage Class | 11 - Combustible Solids |
| | BAPTA Usage And Synthesis |
| Description | BAPTA free acid (85233-19-8) is a selective extracellular Ca2+ chelator. It is a widely used calcium sponge for chelating Ca2+outside of intact cells.1 It’s a useful tool to probe the involvement of extracellular Ca2+ in cellular signaling.2,3 Non-cell-permeable. | | Chemical Properties | White Solid | | Uses | Highly selective calcium chelating reagent. Suitable for the spectrophotometric monitoring of Ca2+ levels. | | Uses | BAPTA is a highly selective calcium chelating reagent. Lipophilic diesters of the chelating agent 1,2-Bis(2 aminophenoxy)ethane-N,N,N',N'-tetraacetic acid (BAPTA) are used for inhibition of proteolytic activities of certain metalloproteinases, calpain and TACE. | | Uses | As calcium chelator; 19F labelled forms for measurement of intracellular calcium. | | Definition | ChEBI: A polyamino carboxylic acid in which bis(carboxymethyl)nitrilo groups are bonded to C-2 and C-2' of 1,1'-[ethane-1,2-diylbis(oxy)]dibenzene. | | General Description | In nature 1,2-Bis(2-Aminophenoxy)ethane-N,N,N′,N′-tetra acetic acid (BAPTA) is a main metabolic product of BAPTA -AM (BAPTA-tetra(actoxymethyl ester), a neuro protective agent in cerebral ischemia, in rats.BAPTA is an intercellular Ca2+ chelator. | | Biological Activity | Selective calcium chelator. | | storage | Store at +4°C | | References | [1] ALBERTO MUÑOZ. Different Stress-Induced Calcium Signatures Are Reported by Aequorin-Mediated Calcium Measurements in Living Cells of Aspergillus fumigatus.[J]. PLoS ONE, 2015: e0138008. DOI:10.1371/journal.pone.0138008
[2] K. WOZNIAK. Extracellular Ca2+ Is Required for Fertilization in the African Clawed Frog, Xenopus laevis[J]. PLoS ONE, 2017. DOI:10.1371/journal.pone.0170405
[3] MIROSLAVA DIDIASOVA. STIM1/ORAI1-mediated Ca2+ Influx Regulates Enolase-1 Exteriorization.[J]. The Journal of Biological Chemistry, 2015: 11983-11999. DOI:10.1074/jbc.m114.598425 |
| | BAPTA Preparation Products And Raw materials |
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