11BETA-HYDROXYPROGESTERONE manufacturers
|
| | 11BETA-HYDROXYPROGESTERONE Basic information |
| Product Name: | 11BETA-HYDROXYPROGESTERONE | | Synonyms: | 11-beta-hydroxy-pregn-4-ene-20-dione;11-beta-hydroxypregn-4-ene-3,20-dione;11-hydroxy-20-dion(11-beta)-pregn-4-ene-;Pregn-4-ene-3,20-dione,11-hydroxy-, (11b)-;11beta-Hydroxyprogesterone, >98%;21-deoxycorticosterone;HYDROXYPROGESTERONE, 11B-;17-acetyl-11-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one | | CAS: | 600-57-7 | | MF: | C21H30O3 | | MW: | 330.46 | | EINECS: | 209-995-8 | | Product Categories: | Steroids | | Mol File: | 600-57-7.mol |  |
| | 11BETA-HYDROXYPROGESTERONE Chemical Properties |
| Melting point | 181～184℃ | | Boiling point | 487.4±45.0 °C(Predicted) | | density | 1.15±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | Acetone (Slightly), Chloroform (Slightly), Methanol (Slightly) | | pka | 14.52±0.70(Predicted) | | form | Solid | | color | White to Off-White | | Water Solubility | 30.84mg/L(37 ºC) |
| | 11BETA-HYDROXYPROGESTERONE Usage And Synthesis |
| Uses | 11β-Hydroxy Progesterone is a derivative of Progesterone (P755900) is a steroid hormone produced by the corpus luteum. Induces maturation and secretory activity of the uterine endothelium; suppresses ovulation. Progesterone is implicated in the etiology of breast cancer.This compound is a contaminant of emerging concern (CECs). | | Definition | ChEBI: 11beta-hydroxyprogesterone is a 11beta-hydroxy steroid that is progesterone substituted by a beta-hydroxy group at position 11. It has a role as a human metabolite and a mouse metabolite. It is functionally related to a progesterone. | | in vivo | 11β-hydroxyprogesterone causes a significant elevation in blood pressure within 3 days, an effect that persisted throughout the 14-day infusion. 11β-hydroxyprogesterone is potently hypertensinogenic in the rat and that this activity depends on an intact adrenal and at least in part on the activation of mineralocorticoid receptors[2]. | | IC 50 | Human Endogenous Metabolite |
| | 11BETA-HYDROXYPROGESTERONE Preparation Products And Raw materials |
|