6-AZATHYMINE manufacturers
- 6-AZATHYMINE
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- $29.00 / 100mg
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2026-05-11
- CAS:932-53-6
- Min. Order:
- Purity: 99.47%
- Supply Ability: 10g
- 6-AzathyMine
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- $0.00 / 100G
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2022-09-12
- CAS:932-53-6
- Min. Order: 1G
- Purity: 98%min
- Supply Ability: 50kg/month
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| | 6-AZATHYMINE Basic information |
| Product Name: | 6-AZATHYMINE | | Synonyms: | 1,2,4-TRIAZINE-3,5(2H,4H)-DIONE, 6-METHYL-;6-AZA-5-METHYLURACIL;6-AZA-2,4-DIHYDROXY-5-METHYL-PYRIMIDINE;6-AZATHYMINE;6-METHYL-1,2,4-TRIAZINE-3,5(2H,4H)-DIONE;3,5-DIHYDROXY-6-METHYL-1,2,4-TRIAZINE;6-Azathymine,98%;6-METHYL-S-TRIAZINE-3,5-DIONE | | CAS: | 932-53-6 | | MF: | C4H5N3O2 | | MW: | 127.1 | | EINECS: | 213-253-9 | | Product Categories: | Vitamins and Derivatives;Nucleic acids | | Mol File: | 932-53-6.mol |  |
| | 6-AZATHYMINE Chemical Properties |
| Melting point | 210-212°C | | Boiling point | 235.85°C (rough estimate) | | density | 1.4748 (rough estimate) | | refractive index | 1.5000 (estimate) | | pka | 7.6(at 25℃) | | form | powder to crystal | | color | White to Almost white | | Merck | 14,903 | | BRN | 126863 | | InChI | InChI=1S/C4H5N3O2/c1-2-3(8)5-4(9)7-6-2/h1H3,(H2,5,7,8,9) | | InChIKey | XZWMZFQOHTWGQE-UHFFFAOYSA-N | | SMILES | N1=C(C)C(=O)NC(=O)N1 | | CAS DataBase Reference | 932-53-6(CAS DataBase Reference) |
| Safety Statements | 22-24/25 | | RTECS | XY8050000 | | HS Code | 2934.10.9000 | | HazardClass | IRRITANT |
| Provider | Language |
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ALFA
| English |
| | 6-AZATHYMINE Usage And Synthesis |
| Uses | 6-Azathymine, a 6-nitrogen analog of thymine, is a potent D-3-aminoisobutyrate-pyruvate aminotransferase inhibitor. 6-Azathymine inhibits the biosynthesis of DNA, and has antibacterial and antiviral activities[1][2][3][4]. | | Definition | ChEBI: A nucleobase analogue that is thymine in which the CH group at position 6 is replaced by nitrogen. | | in vivo | The administration of 6-Azathymine to the mouse leads to the urinary elimination not only of free Azathymine, but also of various metabolites of it. Following the administration of 6-Azathymine-5-14C to mice, radioactivity is found in all tissues investigated, not only in the form of free Azathymine, but also as metabolic derivatives[3]. | | References | [1] N Tamaki, et al. Purification, Characterization and Inhibition of D-3-aminoisobutyrate Aminotransferase From the Rat Liver. Eur J Biochem. 1990 Apr 20;189(1):39-45. DOI:10.1111/j.1432-1033.1990.tb15457.x
[2] W H PRUSOFF, et al. Effect of the Deoxyriboside of 6-azathymine (Azathymidine) on the Biosynthesis of Deoxyribonucleic Acid by Bone Marrow and Neoplastic Cells (In Vitro). Biochim Biophys Acta. 1956 Apr;20(1):209-14. DOI:10.1016/0006-3002(56)90279-7
[3] R A GAITO, et al. Studies on the Metabolism of Thymine and 6-azathymine. Biochem Pharmacol. Apr-May 1962;11:323-36. DOI:10.1016/0006-2952(62)90055-2
[4] B. Gabrielsen, et al. In vitro and in vivo antiviral (RNA) evaluation of orotidine 51-monophosphatedecarboxylase inhibitors and analogues including 6-azauridine-51-(ethylmethoxyalaninyl)phosphate (a 51-monophosphate prodrug). Antiviral Chemistry & Chemotherapy (1994) 5(4), 209-220. |
| | 6-AZATHYMINE Preparation Products And Raw materials |
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