| Company Name: |
Tocopharm Co., Ltd. Gold |
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- 2,4-Lutidine
-
- $100.00
-
2026-05-28
- CAS:108-47-4
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 10000kg
- 2,4-Lutidine
-
- $1.50
-
2026-05-15
- CAS:108-47-4
- Min. Order: 1g
- Purity: 99.0% Min
- Supply Ability: 100 Tons
- 2,4-Lutidine
-
- $1.00
-
2026-03-20
- CAS:108-47-4
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 10 mt
|
| | 2,4-Lutidine Basic information |
| Product Name: | 2,4-Lutidine | | Synonyms: | 2,4-LUTIDINE 98+%;2,4-DIMETHYLPYRIDINE(2,4-LUTIDINE);Dimethylpyridine, 2,4-: (2,4-Lutidine);2,4-Lutidine, 98+% 500ML;2,4-DIMETHYLPYRIDINE FOR SYNTHESIS;2,4-Lutidine 99%;alpha,gamma-Dimethylpyridine;Pyridine,2,4-dimethyl- | | CAS: | 108-47-4 | | MF: | C7H9N | | MW: | 107.15 | | EINECS: | 203-586-8 | | Product Categories: | Building Blocks;C7;Chemical Synthesis;Heterocyclic Building Blocks;Pyridines;Biochemistry;Reagents for Oligosaccharide Synthesis;Heterocyclic Compounds;Organics | | Mol File: | 108-47-4.mol |  |
| | 2,4-Lutidine Chemical Properties |
| Melting point | -60 °C (lit.) | | Boiling point | 159 °C (lit.) | | density | 0.927 g/mL at 25 °C (lit.) | | vapor pressure | 3.28hPa at 25℃ | | FEMA | 4389 | 2,4-DIMETHYLPYRIDINE | | refractive index | n20/D 1.499(lit.) | | Fp | 99 °F | | storage temp. | Flammables area | | solubility | 350g/l | | form | Liquid | | pka | 6.99(at 25℃) | | color | Colorless to Light yellow to Light orange | | Odor | at 0.01 % in dipropylene glycol. smoky phenolic | | Odor Type | smoky | | Water Solubility | 15 g/100 mL (20 ºC) | | Specific Heat Capacity | Cp(liquid): 1.72 J/(g·K), at 25℃ | | Sensitive | Hygroscopic | | JECFA Number | 2151 | | BRN | 1506 | | Henry's Law Constant | 9.9×10-1 mol/(m3Pa) at 25℃, Hawthorne et al. (1985) | | Dielectric constant | 9.5999999999999996 | | Major Application | flavors and fragrances | | Cosmetics Ingredients Functions | PERFUMING | | InChI | 1S/C7H9N/c1-6-3-4-8-7(2)5-6/h3-5H,1-2H3 | | InChIKey | JYYNAJVZFGKDEQ-UHFFFAOYSA-N | | SMILES | Cc1ccnc(C)c1 | | LogP | 1.9 | | CAS DataBase Reference | 108-47-4(CAS DataBase Reference) | | NIST Chemistry Reference | Pyridine, 2,4-dimethyl-(108-47-4) | | EPA Substance Registry System | 2,4-Dimethylpyridine (108-47-4) |
| Hazard Codes | T,F,Xi | | Risk Statements | 10-23/24/25-36/37/38-25-20/21-20/21/22 | | Safety Statements | 16-26-36/37/39-45 | | RIDADR | UN 1992 3/PG 3 | | WGK Germany | 3 | | RTECS | OK9400000 | | F | 8 | | TSCA | TSCA listed | | HazardClass | 3 | | PackingGroup | III | | HS Code | 29333999 | | Storage Class | 3 - Flammable liquids | | Hazard Classifications | Acute Tox. 3 Dermal
Acute Tox. 3 Inhalation
Acute Tox. 3 Oral
Eye Irrit. 2
Flam. Liq. 3
Skin Irrit. 2
STOT SE 3 |
| | 2,4-Lutidine Usage And Synthesis |
| Chemical Properties | Clear pale yellow liquid, discoloring over time | | Chemical Properties | Colorless to pale-yellow clear liquid. | | Uses | 2,4-Lutidine, can be used as a building block in the synthesis of various chemical compounds. It is also used tobacco and aroma component. | | Definition | ChEBI: 2,4-Dimethylpyridine is a member of methylpyridines. | | Preparation |
2,4-Lutidine is produced industrially by extraction from coal tars.
| | Aroma threshold values | High strength odor, recommend smelling in a 0.01% solution or less. | | Safety | The LD50 of 2,4-Lutidine is 200mg/kg (oral, rats).
| | Purification Methods | Dry it with Linde type 5A molecular sieves, BaO or sodium, and fractionally distil it. The distillate (200g) is heated with *benzene (500mL) and conc HCl (150mL) in a Dean and Stark apparatus on a water bath until water no longer separates, and the temperature just below the liquid reaches 80o. When cold, the supernatant *benzene is decanted, and the 2,4-lutidine hydrochloride, after washing with a little *benzene, is dissolved in water (350mL). After removing any *benzene by steam distillation, an aqueous solution of NaOH (80g) is added, and the free lutidine is steam distilled. It is isolated by saturating the distillate with solid NaOH and distilling it through a short column. The precipitation cycle is repeated, then the final distillate is partly frozen in an apparatus at -67.8-68.5o (cooled by acetone/CO2). The crystals are collected, then melted and distilled. [Kyte et al. J Chem Soc 4454 1960.] Alternative purifications are via the picrate m 183-184o (from H2O). [Clarke & Rothwell J Chem Soc 1885 1960], or the hydrobromide [Warnhoff J Org Chem 27 4587 1962]. The latter is precipitated from a solution of lutidine in *benzene by passing dry HBr gas: the salt is recrystallised from CHCl3/methyl ethyl ketone, then decomposed with NaOH, and the free base is extracted into Et2O, dried, evaporated and the residue is distilled. [Beilstein 20 H 244, 20 II 180, 20 III/IV 2718, 20/6 V 19.] |
| | 2,4-Lutidine Preparation Products And Raw materials |
| Raw materials | 2,6-Lutidine-->Motor benzol-->COKEOVENGAS | | Preparation Products | 2-Methylisonicotinic acid-->2-Methyl-4-hydroxymethylpyridine-->4-Methyl-5-nitro-2-pyridinecarboxylic acid-->2-Amino-3,5-dichloro-4,6-dimethyl pyridine-->3-Amino-2-bromo-4,6-dimethylpyridine-->1H-Pyrrolo[2,3-c]pyridine-5-carboxylicacid(9CI)-->3-Amino-4,6-dimethylpyridine-->2-Amino-4,6-dimethylpyridine-->5-Bromo-2,4-dimethylpyridine-->Pyridine-->2,4-Dimethylpiperidine-->4,4',6,6'-bipyridine tetracarboxylic acid |
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