LY 163443 manufacturers
- LY 163443
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- $2180.00
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2026-04-21
- CAS:97581-70-9
- Purity:
- Supply Ability: 10g
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| | LY 163443 Basic information |
| Product Name: | LY 163443 | | Synonyms: | LY 163443;1-[2-Hydroxy-3-propyl-4-[[4-[(1H-tetrazol-5-yl)methyl]phenoxy]methyl]phenyl]ethanone;2'-Hydroxy-3'-propyl-4'-[4-[(1H-tetrazol-5-yl)methyl]phenoxymethyl]acetophenone | | CAS: | 97581-70-9 | | MF: | C20H22N4O3 | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | 97581-70-9.mol |  |
| | LY 163443 Chemical Properties |
| | LY 163443 Usage And Synthesis |
| Uses | LY 163443 is a selective antagonist of leukotrienes D4 (LTD4) and E4 (LTE4). LY 163443 can antagonize LTD4-induced contractions of guinea pig ileum, trachea, and lung parenchyma. LY 163443 also inhibits tracheal contractions to LTE4[1][2]. | | References | [1] Fleisch JH, et, al. Evaluation of LY163443, 1-[2-hydroxy-3-propyl-4-([4- (1H-tetrazol-5-ylmethyl)phenoxy]methyl) phenyl]ethanone, as a pharmacologic antagonist of leukotrienes D4 and E4. Naunyn Schmiedebergs Arch Pharmacol. 1986 May;333(1):70-7. DOI:10.1007/BF00569663
[2] Bitterman H, et, al. Use of a novel peptide leukotriene receptor antagonist, Ly-163443, in splanchnic artery occlusion shock. Prostaglandins Leukot Essent Fatty Acids. 1988 May;32(2):63-70. DOI:10.1016/0952-3278(88)90097-x |
| | LY 163443 Preparation Products And Raw materials |
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