| Company Name: |
BOC Sciences |
| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
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| | NOX-6-18 Basic information |
| Product Name: | NOX-6-18 | | Synonyms: | NOX-6-18;GPR132 antagonist 1 (NOX-6-18);GPR132 antagonist 1|||GPR132-B-160;NOX-6-18（GPR132-B-160）;GPR132 antagonist 1 | | CAS: | 898211-21-7 | | MF: | C18H17NO5S | | MW: | 359.4 | | EINECS: | | | Product Categories: | | | Mol File: | 898211-21-7.mol |  |
| | NOX-6-18 Chemical Properties |
| Boiling point | 584.4±60.0 °C(Predicted) | | density | 1.366±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | | pka | 2.50±0.30(Predicted) | | form | Solid | | color | White to off-white |
| | NOX-6-18 Usage And Synthesis |
| Uses | NOX-6-18 is a highly potent and selective GPR132 antagonist that promotes insulin secretory activity, regulates macrophage reprogramming in pancreatic islets, and reduces weight gain, and may be used as a candidate ingredient for the treatment of diabetes. | | Description | NOX-6-18 (GPR132 antagonist 1) is a potent, selective GPR132 antagonist with IC50 of 17 nM. It modulates macrophage reprogramming within pancreatic islets, decreases weight gain, and enhances glucose metabolism in mice fed a high-fat diet. |
| | NOX-6-18 Preparation Products And Raw materials |
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