- Boc-D-Ser(Bzl)-OL
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- $0.00 / 1kg
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2026-02-02
- CAS:79069-15-1
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 1T+
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| | N-Boc-(S)-2-amino-3-benzyloxy-1-propanol Basic information |
| | N-Boc-(S)-2-amino-3-benzyloxy-1-propanol Chemical Properties |
| Melting point | 66-69 °C(lit.) | | alpha | -14 º (c=1 in chloroform) | | Boiling point | 443.1±40.0 °C(Predicted) | | density | 1.105 | | storage temp. | Inert atmosphere,2-8°C | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | pka | 11.58±0.46(Predicted) | | form | Powder | | Appearance | White to off-white Solid | | InChI | InChI=1S/C15H23NO4/c1-15(2,3)20-14(18)16-13(9-17)11-19-10-12-7-5-4-6-8-12/h4-8,13,17H,9-11H2,1-3H3,(H,16,18)/t13-/m0/s1 | | InChIKey | MSIDLARYVJJEQY-ZDUSSCGKSA-N | | SMILES | C(OC(C)(C)C)(=O)N[C@@H](CO)COCC1=CC=CC=C1 | | CAS DataBase Reference | 79069-15-1(CAS DataBase Reference) |
| WGK Germany | 3 | | HS Code | 2924297099 |
| | N-Boc-(S)-2-amino-3-benzyloxy-1-propanol Usage And Synthesis |
| Chemical Properties | White to off-white solid | | Synthesis | Under an atmosphere of argon, to a solution of 2,5-dioxopyrrolidin-1-yl O-benzyl-N-t-butoxycarbonyl-L-serinate (4.41 g) in tetrahydrofuran(30 mL) was added sodium borohydride (644 mg) in ice bath and the mixture was stirred at room temperature overnight. Water was added to the reaction solution, which was extracted with ethyl acetate. The organic layer was washed with an aqueous saturated ammonium chloride solution and brine, dried over anhydrous magnesium sulfate, and concentrated to give N-Boc-(S)-2-amino-3-benzyloxy-1-propanol.
 | | References | [1] Synthetic Communications, 1996, vol. 26, # 13, p. 2511 - 2522
[2] Nucleosides and Nucleotides, 1999, vol. 18, # 8, p. 1845 - 1861
[3] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 2, p. 702 - 713 |
| | N-Boc-(S)-2-amino-3-benzyloxy-1-propanol Preparation Products And Raw materials |
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