- MONO-METHYL GLUTARATE
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- $30.00 / 1KG
-
2025-06-27
- CAS:1501-27-5
- Min. Order: 50KG
- Purity: 99%
- Supply Ability: 500000kg
- MONO-METHYL GLUTARATE
-
- $30.00 / 1kg
-
2025-06-20
- CAS:1501-27-5
- Min. Order: 1kg
- Purity: 0.99
- Supply Ability: 10 tons
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| | MONO-METHYL GLUTARATE Basic information |
| Product Name: | MONO-METHYL GLUTARATE | | Synonyms: | 5-Methoxy-5-oxopentanoic acid;Methyl glutarate,mono;Monomethyl ester of glutaric acid;pentanedioicacid,monomethylester;pentanedioicacidmonomethylester;MONOMETHYL PENTANE-1,5-DIOATE;MONO-METHYL GLUTARATE;TIMTEC-BB SBB007943 | | CAS: | 1501-27-5 | | MF: | C6H10O4 | | MW: | 146.14 | | EINECS: | 216-116-1 | | Product Categories: | Pyridines;CMLLYL;Acids & Esters | | Mol File: | 1501-27-5.mol |  |
| | MONO-METHYL GLUTARATE Chemical Properties |
| Boiling point | 150-151 °C/10 mmHg (lit.) | | density | 1.169 g/mL at 25 °C (lit.) | | refractive index | n20/D 1.438(lit.) | | Fp | >230 °F | | storage temp. | Sealed in dry,Room Temperature | | solubility | Chloroform, Methanol (Slightly) | | pka | 4.62±0.10(Predicted) | | form | clear liquid | | color | Colorless to Almost colorless | | Water Solubility | Slightly soluble in water. | | BRN | 1762381 | | InChI | 1S/C6H10O4/c1-10-6(9)4-2-3-5(7)8/h2-4H2,1H3,(H,7,8) | | InChIKey | IBMRTYCHDPMBFN-UHFFFAOYSA-N | | SMILES | COC(=O)CCCC(O)=O | | CAS DataBase Reference | 1501-27-5(CAS DataBase Reference) | | EPA Substance Registry System | Pentanedioic acid, monomethyl ester (1501-27-5) |
| Risk Statements | 36/38 | | Safety Statements | 23-24/25 | | WGK Germany | 3 | | TSCA | TSCA listed | | HS Code | 29171900 | | Storage Class | 10 - Combustible liquids |
| | MONO-METHYL GLUTARATE Usage And Synthesis |
| Chemical Properties | Clear light yellow liquid | | Uses | It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff. | | Definition | ChEBI: A dicarboxylic acid monoester that the monomethyl ester of glutaric acid. | | Synthesis Reference(s) | Journal of the American Chemical Society, 107, p. 1365, 1985 DOI: 10.1021/ja00291a042
Tetrahedron, 49, p. 8465, 1993 DOI: 10.1016/S0040-4020(01)81929-3 | | Synthesis | GENERAL METHOD: A methanol (MeOH, 150 mL) solution of potassium hydroxide (KOH, 5.87 g, 104.65 mmol) was added to dimethyl glutarate (13.15 g, 90 mmol) and the reaction mixture was stirred for 4 hours at room temperature. After completion of the reaction, the solvent was removed under reduced pressure and extracted by adding ether (Et2O, 100 mL) and water (H2O, 200 mL). The organic layer was separated, washed with saturated brine, dried over anhydrous magnesium sulfate (MgSO4) and concentrated under reduced pressure to give compound 3a as a yellow oil (4.61 g, 32% yield). The aqueous layer was acidified to pH 3 with concentrated hydrochloric acid and subsequently extracted with ether (3 x 100 mL). The organic phases were combined, washed with saturated brine (3 x 100 mL) and dried over anhydrous magnesium sulfate (MgSO4). The solvent was removed under reduced pressure to give a mixture of white solid and oil. After filtration and vacuum concentration, the compound was purified by silica gel column chromatography to give compound 4a as a colorless oil (5.79 g, 44% yield). | | IC 50 | Human Endogenous Metabolite | | References | [1] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 12, p. 3865 - 3872
[2] Chemistry Letters, 1995, # 7, p. 539 - 540 |
| | MONO-METHYL GLUTARATE Preparation Products And Raw materials |
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