DBCO-PEG4-DBCO manufacturers
- DBCO-PEG4-DBCO
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2025-08-22
- CAS:2182601-68-7
- Purity:
- Supply Ability: 10g
- DBCO-PEG4-DBCO
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2025-06-07
- CAS:2182601-68-7
- Min. Order: 25mg
- Purity: >99.00%
- Supply Ability: 100mg
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| | DBCO-PEG4-DBCO Basic information |
| Product Name: | DBCO-PEG4-DBCO | | Synonyms: | DBCO-PEG4-DBCO;Bis-DBCO-NHCO-PEG4;4,7,10,13-Tetraoxahexadecanediamide, N1,N16-bis[3-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]-;DBCO-NHCO-PEG4-CONH-DBCO | | CAS: | 2182601-68-7 | | MF: | C48H50N4O8 | | MW: | 810.93 | | EINECS: | | | Product Categories: | | | Mol File: | 2182601-68-7.mol |  |
| | DBCO-PEG4-DBCO Chemical Properties |
| Boiling point | 1104.6±65.0 °C(Predicted) | | density | 1.30±0.1 g/cm3(Predicted) | | storage temp. | -20°C, sealed storage, away from moisture | | form | Solid | | pka | 14.84±0.46(Predicted) | | color | White to yellow |
| | DBCO-PEG4-DBCO Usage And Synthesis |
| Description | DBCO-PEG4-DBCO is a homobifunctional PEG linker containing two DBCO groups and a hydrophilic PEG spacer arm. DBCO will react with azide-bearing compounds or biomolecules to form a stable triazole linkage without copper catalyst. The hydrophilic PEG spacer arm can increase water solubility and membrane permability. | | Uses | DBCO-PEG4-DBCO is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-PEG4-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. | | IC 50 | Cleavable Linker; PEGs | | References | [1] Adam TIBBLES, et al. Engineered O-glycosylation in recombinant polypeptides via heterologous glycosylation sites. WO2019122234A1. |
| | DBCO-PEG4-DBCO Preparation Products And Raw materials |
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