Azadibenzocyclooctyne-PEG1-N-hydroxysuccinimidyl ester

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Company Name: 9i LLC
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Email: MWan@NiNeiLab.com
Products Intro: Product Name:Azadibenzocyclooctyne-PEG1-N-hydroxysuccinimidyl ester; DBCO-PEG1-NHS Ester; DBCO-NH-PEG1-CH2CH2COONHS ester
Purity:97% Package:100mg;500mg;1g;5g;10g Remarks:JA1500
Company Name: TargetMol Chemicals Inc.
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Email: marketing@targetmol.com
Products Intro: Product Name:DBCO-PEG1-NHS ester
CAS:2228857-34-7
Purity:98.00% Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: XIAMEN SINOPEG BIOTECH CO., LTD.
Tel: +86-0592-7761068 15616186207
Email: changaiwei@sinopeg.com
Products Intro: Product Name:DBCO-PEG1-NHS
CAS:2228857-34-7
Purity:98% Package:1g|10g|100g
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354;
Email: support@targetmol.com
Products Intro: Product Name:DBCO-PEG1-NHS ester
CAS:2228857-34-7
Package:2mg;121USD
Company Name: Jilin Chinese Academy of Sciences-yanshen Technology
Tel: 18143011203
Email: info@chemextension.com
Products Intro: Product Name:DBCO-PEG1-NHS ester
CAS:2228857-34-7
Purity:95%+ Package:1g;5g;10g;25g;50g;100g; Remarks:accept Custom Synthesis Services, support large packing

Azadibenzocyclooctyne-PEG1-N-hydroxysuccinimidyl ester manufacturers

  • DBCO-PEG1-NHS
  • DBCO-PEG1-NHS pictures
  • 2026-07-24
  • CAS:2228857-34-7
  • Min. Order: 1g
  • Purity: 98%
  • Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
Azadibenzocyclooctyne-PEG1-N-hydroxysuccinimidyl ester Basic information
Product Name:Azadibenzocyclooctyne-PEG1-N-hydroxysuccinimidyl ester
Synonyms:Azadibenzocyclooctyne-PEG1-N-hydroxysuccinimidyl ester;DBCO-NH-PEG1-CH2CH2COONHS ester;DBCO-PEG1-NHS Ester;DBCO-NH-PEG1-CH2CH2COONHS;2,5-Dioxo-1-pyrrolidinyl 3-[2-[[4-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-1,4-dioxobutyl]amino]ethoxy]propanoate
CAS:2228857-34-7
MF:C28H27N3O7
MW:517.54
EINECS:
Product Categories:
Mol File:2228857-34-7.mol
Azadibenzocyclooctyne-PEG1-N-hydroxysuccinimidyl ester Structure
Azadibenzocyclooctyne-PEG1-N-hydroxysuccinimidyl ester Chemical Properties
density 1.39±0.1 g/cm3(Predicted)
solubility Soluble in DMSO, DCM, DMF
form Solid
pka15.12±0.46(Predicted)
color Off-white to light yellow
Safety Information
MSDS Information
Azadibenzocyclooctyne-PEG1-N-hydroxysuccinimidyl ester Usage And Synthesis
DescriptionDBCO-PEG1-NHS Ester is a PEG containing molecule containing an NHS ester moiety that can react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond. DBCO is commonly used for copper-free Click Chemistry reactions.
UsesDBCO-PEG1-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-PEG1-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
IC 50PEGs
References[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Azadibenzocyclooctyne-PEG1-N-hydroxysuccinimidyl ester Preparation Products And Raw materials
Tag:Azadibenzocyclooctyne-PEG1-N-hydroxysuccinimidyl ester(2228857-34-7) Related Product Information
DBCO-PEG1-amine 5,8,11,14,17,20-Hexaoxa-2,23-diazaheptacosanoic acid, 27-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-24,27-dioxo-, 1,1-dimethylethyl ester DBCO-PEG3-CH2CO-NHS DBCO-PEG4-amine DBCO-PEG4-SE DBCO-NHS Ester DBCO-PEG2-NH-Boc DBCO-PEG4-DBCO DBCO-(CH2)2-NH2-CO-(CH2)3COOH-NHS DBCO-PEG3-acid Azadibenzocyclooctyne-Biotin conjugate 4,7,10,13-Tetraoxa-16-azaheneicosanoic acid, 21-(11,12-dihydrodibenz[b,f]azocin-5(6H)-yl)-17,21-dioxo-, 2,3,5,6-tetrafluorophenyl ester DBCO-NH-(CH2)4COOH DBCO-PEG3-amine DBCO-NH-Boc