Diethyl butylmalonate

Diethyl butylmalonate Suppliers list

Company Name:	Shandong Yukun Chemical Industry Co. LTD Gold
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Email:	sales@yukunchem.com

Company Name:	Shanghai YouPeng Chemical Co. Ltd. Gold
Tel:	021-69005955 13701776567;
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Company Name:	Beijing Donghualituo Techonlogy Development Co.,Ltd.
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Diethyl butylmalonate manufacturers

Diethyl butylmalonate Basic information

Product Name:	Diethyl butylmalonate
Synonyms:	BMDE;BUTYLMALONIC ACID DIETHYL ESTER;ETHYL BUTYLMALONATE;DIETHYL N-BUTYLMALONATE;DIETHYL BUTYLMALONATE;LABOTEST-BB LTBB001318;N-BUTYL DIETHYL MALONATE;N-BUTYLMALONIC ACID DIETHYL ESTER
CAS:	133-08-4
MF:	C11H20O4
MW:	216.27
EINECS:	205-089-1
Product Categories:	TheMalonateRamificationProducts;Pharmaceutical Intermediates;C10 to C11;Carbonyl Compounds;Esters
Mol File:	133-08-4.mol

Diethyl butylmalonate Chemical Properties

Melting point	238 °C
Boiling point	235-240 °C (lit.)
density	0.983 g/mL at 25 °C (lit.)
vapor pressure	1Pa at 20℃
refractive index	n20/D 1.422(lit.)
Fp	201 °F
storage temp.	Sealed in dry,Room Temperature
solubility	DMSO : 100 mg/mL (462.38 mM; Need ultrasonic)\|
pka	13.47±0.46(Predicted)
form	clear liquid
color	Colorless to Almost colorless
Specific Gravity	0.975 (20/4℃)
Water Solubility	330mg/L at 20℃
Merck	14,1576
BRN	608785
InChI	1S/C11H20O4/c1-4-7-8-9(10(12)14-5-2)11(13)15-6-3/h9H,4-8H2,1-3H3
InChIKey	RPNFNBGRHCUORR-UHFFFAOYSA-N
SMILES	CCCCC(C(=O)OCC)C(=O)OCC
LogP	3.4 at 23℃
CAS DataBase Reference	133-08-4(CAS DataBase Reference)
NIST Chemistry Reference	Diethyl butylmalonate(133-08-4)

Safety Information

MSDS Information

Diethyl butylmalonate Usage And Synthesis

Synthesis	Diethyl malonate is mixed with sodium ethoxide, and then chlorobutane is added to form the reaction. The crude product is separated and recovered ethanol, washed and dehydrated to obtain Diethyl butylmalonate.
Chemical Properties	CLEAR COLOURLESS LIQUID
Uses	Diethyl butylmalonate is used as a reagent in the synthesis of 2,5-dihydropyrrole formyl hydroxyamino derivatives as peptide deformylase inhibitors against drug-resistant bacteria.
Synthesis Reference(s)	Organic Syntheses, Coll. Vol. 1, p. 250, 1941 The Journal of Organic Chemistry, 44, p. 3492, 1979 DOI: 10.1021/jo01334a009
General Description	Diethyl malonate (DEM) undergoes alkylation by ethyliodide, which is used to study the phase transfer catalysis (PTC) technique.
Flammability and Explosibility	Not classified

Diethyl butylmalonate Preparation Products And Raw materials

Raw materials	Sodium ethoxide-->Diethyl malonate-->Malonic acid-->1-Chlorobutane-->Propanedioic acid,2-butyl-2-(2-propen-1-yl)-, 1,3-diethyl ester-->Propanedioic acid,2-butylidene-, 1,3-diethyl ester-->diethyl methylidenemalonate-->1-Butanol-->Diethyl oxalate-->Butylamine-->Ethyl Hexanoate-->1-Bromobutane
Preparation Products	Phenylbutazone-->Butyl triethyl malonate-->MOFEBUTAZONE-->Diethyl dibutylmalonate

Tag:Diethyl butylmalonate(133-08-4) Related Product Information

Ethyl malonyl chloride Diethyl allylmalonate Diethyl dipropylmalonate Diethyl phenylmalonate Diethyl ketomalonate Ethylene glycol diethyl ether Diisopropyl malonate Mefenpyr-diethyl Diethyl methylmalonate Diethyl isopropylmalonate Diethyl bis(hydroxymethyl)malonate Diethyl benzylmalonate Diethyl oxalate Diethyl malonate 2-Aminodiethylmalonate Diethyl dimethylmalonate Diethyl diethylmalonate N-(n-butyl)thiophosphoric triamide