Nalpha-Fmoc-L-serine tert-butyl ester

Nalpha-Fmoc-L-serine tert-butyl ester Suppliers list

Company Name:	Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel:	4006356688 18621169109
Email:	market03@meryer.com

Company Name:	TCI (Shanghai) Development Co., Ltd.
Tel:	021-67121386
Email:	Sales-CN@TCIchemicals.com

Nalpha-Fmoc-L-serine tert-butyl ester manufacturers

Nalpha-Fmoc-L-serine tert-butyl ester Basic information

Product Name:	Nalpha-Fmoc-L-serine tert-butyl ester
Synonyms:	N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-SERINE ALPHA-T-BUTYL ESTER;NALPHA-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-L-SERINE TERT-BUTYL ESTER;-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-serine tert-Butyl Ester;N alfa-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-serine tert-Butyl Ester;Nα-Fmoc-L-serine tert-Butyl Ester;Nalpha-Fmoc-L-serine tert-Butyl Ester Fmoc-Ser-OtBu;-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-serine tert-Butyl Ester;N-[(9-fluorenyl)methoxycarbonyl]-L-serine tert-butyl ester
CAS:	110797-35-8
MF:	C22H25NO5
MW:	383.44
EINECS:
Product Categories:	Amino Acid tert-Butyl Esters;Amino Acids;Amino Acids (C-Protected);Amino Acids (N-Protected);Biochemistry;Fmoc-Amino Acids;Reagents for Oligosaccharide Synthesis
Mol File:	110797-35-8.mol

Nalpha-Fmoc-L-serine tert-butyl ester Chemical Properties

Melting point	127 °C
Boiling point	588.4±45.0 °C(Predicted)
density	1.216±0.06 g/cm3(Predicted)
refractive index	11 ° (C=1, CHCl3)
storage temp.	Sealed in dry,2-8°C
solubility	soluble in Chloroform
pka	10.07±0.46(Predicted)
form	powder to crystal
color	White to Orange to Green
InChIKey	ZYOWIDHANLLHNO-IBGZPJMESA-N

Safety Information

HS Code

2924.19.8000

MSDS Information

Nalpha-Fmoc-L-serine tert-butyl ester Usage And Synthesis

Uses	Fmoc-Ser-OtBu is a serine derivative[1].
Synthesis	L-serine tert-butyl ester was added to a round-bottomed flask, 10% aqueous sodium carbonate was added and stirred to dissolve, then dioxane was added, and a 10% dioxane solution of 9-fluorenylmethoxycarbonyl chloride was slowly added dropwise into the reaction solution under an ice bath, and after the dropwise addition was completed the reaction was carried out for 2 hrs in an ice bath, and then at room temperature for 8 hrs, and the reaction was diluted with the addition of water, and the extract was carried out with ether 4 times, the aqueous layer was placed in an ice bath, the pH was adjusted with concentrated hydrochloric acid until the Congo red paper showed blue, placed in a refrigerator overnight, the white precipitate was extracted with ethyl acetate, the combined organic solution was washed with water, the organic layer was dried with anhydrous magnesium sulfate, and pumped dry to get the product tert-butyl N-(9-fluorenylmethoxycarbonyl)-L-serinate.
References	[1] Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144. DOI:10.1080/10408398.2012.708368

Nalpha-Fmoc-L-serine tert-butyl ester Preparation Products And Raw materials

Tag:Nalpha-Fmoc-L-serine tert-butyl ester(110797-35-8) Related Product Information

Fmoc-Ser(tBu)-Ser(Psi(Me,Me)pro)-OH Fmoc-Ser(Allyl)-OH D-Serine, O-ethyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]- Fmoc-Trp(N-CH2COOAll)-OH Fmoc-(S)-2-amino-6-phenylhexanoic acid Fmoc-O-trityl-L-serine N-Fmoc-6-Methoxy-L-tryptophan Fmoc-Trp(Boc)-OH (4S)-3-(FMoc-Thr(tBu))-2,2-diMethyl-oxazolidine-4-carboxylic acid Fmoc-N-(propyl)-glycine Fmoc-Thr(Allyl)-OH Fmoc-O-trityl-L-threonine Fmoc-N-(2,4,6-trimethoxybenzyl)-glycine Fmoc-Thr(GalNAc(Ac)3-alpha-d)-OH 4-(Fmoc-amino)-tetrahydropyran-4-carboxylic acid Boc-D-Pro-OSu Fmoc-Ser(GalNAc(Ac)3-alpha-d)-OH Nalpha-Fmoc-L-threonine tert-butyl ester