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| | Fmoc-O-trityl-L-threonine Basic information |
| | Fmoc-O-trityl-L-threonine Chemical Properties |
| Melting point | 70-85°C | | Boiling point | 753.0±60.0 °C(Predicted) | | density | 1.241±0.06 g/cm3(Predicted) | | storage temp. | Store at -15°C to -25°C. | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | Powder | | pka | 3.31±0.10(Predicted) | | Major Application | peptide synthesis | | InChIKey | JARBLLDDSTVWSM-IJAHGLKVSA-N | | SMILES | N([C@@H]([C@H](OC(c6ccccc6)(c5ccccc5)c4ccccc4)C)C(=O)O)C(=O)OCC1c2c(cccc2)c3c1cccc3 | | CAS DataBase Reference | 133180-01-5(CAS DataBase Reference) |
| WGK Germany | WGK 2 | | HS Code | 2924297099 | | Storage Class | 11 - Combustible Solids |
| | Fmoc-O-trityl-L-threonine Usage And Synthesis |
| Chemical Properties | White to off-white crystalline powder | | Uses | peptide synthesis | | General Description | The side-chain Trt group can be selectively removed with 1% TFA in DCM containing 5% TIS, enabling the side-chain hydroxyl group to be selectively modified whilst the derivative is attached to the solid support. This is an excellent derivative for the synthesis of phosphothreonine containing peptides and peptides modified at the threonine side-chain [1]. The use of trityl protected amino acids was shown to result in purer products than when standard t-Bu protected amino acids were utilized [2].
The product number for this product was previously 04-12-1141.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”. | | reaction suitability | reaction type: Fmoc solid-phase peptide synthesis |
| | Fmoc-O-trityl-L-threonine Preparation Products And Raw materials |
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