| Company Name: |
ShangHai Biochempartner Co.,Ltd
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| Tel: |
177-54423994 17754423994 |
| Email: |
2853530910@QQ.com |
| Products Intro: |
Product Name:SU4984 CAS:186610-89-9 Purity:98% HPLC LCMS Package:100MG;1G
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CIVENTICHEM CV-409 manufacturers
- SU4984
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- $41.00 / 10mg
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2026-01-05
- CAS:186610-89-9
- Min. Order:
- Purity: 97.20%
- Supply Ability: 10g
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| | CIVENTICHEM CV-409 Basic information |
| Product Name: | CIVENTICHEM CV-409 | | Synonyms: | CIVENTICHEM CV-409;inhibit,growth,Fibroblast growth factor receptor,Insulin Receptor,fibroblast,insulin,SU4984,SU 4984,FGFR1,factor,Platelet-derived growth factor receptor,SU-4984,FGFR,kinase,tyrosine,platelet,cancer,PDGFR,Inhibitor;1-Piperazinecarboxaldehyde, 4-[4-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]phenyl]-;SU4984, 10 mM in DMSO | | CAS: | 186610-89-9 | | MF: | C20H19N3O2 | | MW: | 333.38 | | EINECS: | | | Product Categories: | | | Mol File: | 186610-89-9.mol |  |
| | CIVENTICHEM CV-409 Chemical Properties |
| Boiling point | 649.1±55.0 °C(Predicted) | | density | 1.340±0.06 g/cm3(Predicted) | | storage temp. | 4°C, protect from light | | solubility | DMSO : 50 mg/mL (149.98 mM) | | form | Orange to red crystalline solid. | | pka | 12.93±0.20(Predicted) | | color | White to yellow |
| | CIVENTICHEM CV-409 Usage And Synthesis |
| Uses | SU4984 is a protein tyrosine kinase inhibitor, with an IC50 of 10-20 μM for fibroblast growth factor receptor 1 (FGFR1). SU4984 is also inhibits platelet-derived growth factor receptor, and insulin receptor. SU4984 can be used for the research of cancer[1][2][3]. | | IC 50 | FGFR1: 10-20 μM (IC50) | | References | [1] Mohammadi M, et, al. Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors. Science. 1997 May 9;276(5314):955-60. DOI:10.1126/science.276.5314.955 [2] Ma Y, et, al. Indolinone derivatives inhibit constitutively activated KIT mutants and kill neoplastic mast cells. J Invest Dermatol. 2000 Feb;114(2):392-4. DOI:10.1046/j.1523-1747.2000.00888.x |
| | CIVENTICHEM CV-409 Preparation Products And Raw materials |
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