15(S)-15-Methyl prostaglandin E1

Request For Quotation
15(S)-15-Methyl prostaglandin E1 Suppliers list
Company Name: Quality Control Solutions Ltd.  
Tel: 0755-66853366 13670046396
Email: orders@qcsrm.com
Company Name: Shanghai EFE Biological Technology Co., Ltd.  
Tel: 021-65675885 18964387627
Email: info@efebio.com
Company Name: Shenzhen Polymeri Biochemical Technology Co., Ltd.  
Tel: +86-400-002-6226
Email: sales@rrkchem.com
Company Name: Changzhou Xianglong Pharmaceutical Technology Co., Ltd.,  
Tel: 18915873328 18915873328
Email: sales@xianglongpharm.com
15(S)-15-Methyl prostaglandin E1 Basic information
Product Name:15(S)-15-Methyl prostaglandin E1
Synonyms:9-OXO-11ALPHA,15S-DIHYDROXY-15-METHYL-PROST-13E-EN-1-OIC ACID;15(S)-15-methyl Prostaglandin E1;OMNFCPCBKCERJP-XBZFKEOQSA-N;15(S)-15-methyl PGE1;9-oxo-11α,15S-dihydroxy-15-methyl-prost-13E-en-1-oic acid;Prost-13-en-1-oic acid,11,15-dihydroxy-15-methyl-9-oxo-, (11a,13E,15S)- (9CI);Prost-13-en-1-oic acid, 11,15-dihydroxy-15-methyl-9-oxo-, (11α,13E,15S)- (9CI);15(S)-15-methyl Prostaglandin E
CAS:35700-26-6
MF:C21H36O5
MW:368.51
EINECS:
Product Categories:
Mol File:35700-26-6.mol
15(S)-15-Methyl prostaglandin E1 Structure
15(S)-15-Methyl prostaglandin E1 Chemical Properties
Boiling point 534.9±50.0 °C(Predicted)
density 1.118±0.06 g/cm3(Predicted)
solubility DMF: >100 mg/ml (from PGE1); DMSO: >50 mg/ml (from PGE1); Ethanol: >50 mg/ml (from PGE1); PBS pH 7.2: >1.6 mg/ml (from PGE1)
pka4.77±0.10(Predicted)
Safety Information
MSDS Information
15(S)-15-Methyl prostaglandin E1 Usage And Synthesis
Description15(S)-15-methyl Prostaglandin E1 (15(S)-15-methyl PGE1) is a metabolically stable synthetic analog of PGE1 . In sharp contrast to the bronchodilatory effects of PGE1, 15(S)-15-methyl PGE1 is a weak constrictor of human respiratory tract smooth muscle.1
Uses15-Methylprostaglandin E1 (15S-15-Methyl-PGE1) exhibits a positiv chronotropic effect, increases the heart rate and levels of nicardipine[1].
DefinitionChEBI: 15-Methyl-15S-Prostaglandin E1 is a prostanoid.
in vivo

15-Methylprostaglandin E1 (0.01-100 nM) induces a long-lasting heart rate increases in a dose-dependent manner without alters in heart contractility in guinea pig, which is probably altered by Na+/Ca+ concentration.

Animal Model:guinea pigs with isolated atria[1]
Dosage:0.01-100 nM
Administration:
Result:Increased heart rate.
References1. Karim, S.M.M., Adaikan, P.G., and Kottegoda, S.R. Prostaglandins and human respiratory tract smooth muscle: Structure activity relationship Adv. Prostaglandin Thromboxane Res. 7,969-980(1980).
15(S)-15-Methyl prostaglandin E1 Preparation Products And Raw materials
Tag:15(S)-15-Methyl prostaglandin E1(35700-26-6) Related Product Information
15(S)-15-Methyl prostaglandin E1 1,11alpha,15S-trihydroxy-prost-13e-en-9-one delta 10 trans heptadecenoic acid 11-Deoxy prostaglandin E1 cis-2,5-Dimethyl-3-hexene 15(S)-15-Methyl prostaglandin Doxaprost Prostaglandin E1